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The map label for this gene is engA [H]

Identifier: 116620165

GI number: 116620165

Start: 1283234

End: 1284559

Strand: Reverse

Name: engA [H]

Synonym: Acid_1038

Alternate gene names: 116620165

Gene position: 1284559-1283234 (Counterclockwise)

Preceding gene: 116620169

Following gene: 116620164

Centisome position: 12.89

GC content: 60.48

Gene sequence:

>1326_bases
ATGTCAACTGCCAACCCCACGGTGGTCATTGTGGGCAGGCCCAACGTCGGAAAGTCCACCCTTTTCAACCGCATCACTGG
ACAGCGCCGCGCAATTGTCGGGGATGAACCCGGGATTACGCGCGACCGCCTTCATGGGGCTGCCGAACACGACGGCCGGC
ACTTCGAACTGATCGACACCGGCGGAATCGTCGTTCACGATCAGGAATATATCCCCGCCCAGATATTGAAGCAGGCGGAG
TTCGCGCTGAAAGCGGCCGACCACATCATCTTCCTGGTGGACGGGCGCGCCGAAATCACGGGCAGCGATCGCGACCTGGC
GCAAATGCTGAAGAAGCTCGGAAAACCGGTTTCGCTGGCGGTCAACAAGATCGACGCGCAGGTGCGGCAGGACCTGGTGA
ACGAGTTCTACGGACTGGGGATCGCGGACGTGTTCGCCATCTCGGCGGAGCACGGCACCGGCGTGGACGCGATGCTCGAC
CGGGTGACGGAAGGCTTCGCGCGCGGCGAAAAGCCCACAGCGGAAAGCACCGAGCCGAAGGGCATCAAGGTCGCGATCAT
CGGGCGGCCGAACGTCGGGAAATCGACATTGCTGAATGCGCTCACCGGAGCGGATCGCGCGATTGTATCACCGATCGCCG
GGACCACGCGCGACGCAGTCGACGAGACGGTGTCGCACGATGGCCAGGAGTACGTGTTCGTGGACACGGCGGGCATCCGG
CGCAAGGGCAAGACACACGATATGGCGGAGAAGCTGAGCGTGGTGATGGCGCGCCGGCACATCCGCATGGCGCACGTGGT
GCTGCTGGTATTGGACGCGACGGAAGGCGTGGTGGCGCTGGATACGACGATCGCCGGCTACGCGCACGAAGGTGGACGCG
CGGTGATCATCTGCGTGAACAAATGGGACGAGGTCAAGGGGCAGGCGGCGCAAAAGAAGAACGAATTCGAGCAACAGATC
CGCGACGAATTCAAATTTCTGGATTACGCACCGGTGGTCTTTCTTTCGGCGAAATCGGGTTCAAACGTACCAAAGCTGTT
CCGGCTGATCAAAGAGATTTACGAATCGGCCTCGAAGCGGGTGACTACGGGCGAGTTGAACCGGTTTGTGGATCACCTGC
ACTTTGAGGAGCGGAAGATCTTTTACATTACGCAGCATTCGATCCGCCCGCCAGCGTTCGCGGTGTTTACAGACAAGGGT
CCGGCGCTGCATTTCTCGCACGAGCGGTACCTGGTGAATCAACTCCGTAAGCAGTTCGGGTTCAAGGGAACGCCGATTTT
GCTGCAGACCAAAGCCAAGGGCAAGGGCAAGCCGAGAGGCAAGTAA

Upstream 100 bases:

>100_bases
CAAGTTGTTCCCAAAACTGCAAGTCGTTGAGCCGGCGTCGCGGCGGGCAAGGAAGCAAAAGCGGGTTCGGCGCCGGTGGG
GCCTGCTATTATAAGACTTC

Downstream 100 bases:

>100_bases
GCGGCATTGCCTTTTGCCCGTACTTCCCCCTATGCTAGGAGGAGCAGTATCATGATCGTAATCATAATGAATACAGGAGG
GCGGCTCTATGTGGAATAAG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSTANPTVVIVGRPNVGKSTLFNRITGQRRAIVGDEPGITRDRLHGAAEHDGRHFELIDTGGIVVHDQEYIPAQILKQAE
FALKAADHIIFLVDGRAEITGSDRDLAQMLKKLGKPVSLAVNKIDAQVRQDLVNEFYGLGIADVFAISAEHGTGVDAMLD
RVTEGFARGEKPTAESTEPKGIKVAIIGRPNVGKSTLLNALTGADRAIVSPIAGTTRDAVDETVSHDGQEYVFVDTAGIR
RKGKTHDMAEKLSVVMARRHIRMAHVVLLVLDATEGVVALDTTIAGYAHEGGRAVIICVNKWDEVKGQAAQKKNEFEQQI
RDEFKFLDYAPVVFLSAKSGSNVPKLFRLIKEIYESASKRVTTGELNRFVDHLHFEERKIFYITQHSIRPPAFAVFTDKG
PALHFSHERYLVNQLRKQFGFKGTPILLQTKAKGKGKPRGK

Sequences:

>Translated_441_residues
MSTANPTVVIVGRPNVGKSTLFNRITGQRRAIVGDEPGITRDRLHGAAEHDGRHFELIDTGGIVVHDQEYIPAQILKQAE
FALKAADHIIFLVDGRAEITGSDRDLAQMLKKLGKPVSLAVNKIDAQVRQDLVNEFYGLGIADVFAISAEHGTGVDAMLD
RVTEGFARGEKPTAESTEPKGIKVAIIGRPNVGKSTLLNALTGADRAIVSPIAGTTRDAVDETVSHDGQEYVFVDTAGIR
RKGKTHDMAEKLSVVMARRHIRMAHVVLLVLDATEGVVALDTTIAGYAHEGGRAVIICVNKWDEVKGQAAQKKNEFEQQI
RDEFKFLDYAPVVFLSAKSGSNVPKLFRLIKEIYESASKRVTTGELNRFVDHLHFEERKIFYITQHSIRPPAFAVFTDKG
PALHFSHERYLVNQLRKQFGFKGTPILLQTKAKGKGKPRGK
>Mature_440_residues
STANPTVVIVGRPNVGKSTLFNRITGQRRAIVGDEPGITRDRLHGAAEHDGRHFELIDTGGIVVHDQEYIPAQILKQAEF
ALKAADHIIFLVDGRAEITGSDRDLAQMLKKLGKPVSLAVNKIDAQVRQDLVNEFYGLGIADVFAISAEHGTGVDAMLDR
VTEGFARGEKPTAESTEPKGIKVAIIGRPNVGKSTLLNALTGADRAIVSPIAGTTRDAVDETVSHDGQEYVFVDTAGIRR
KGKTHDMAEKLSVVMARRHIRMAHVVLLVLDATEGVVALDTTIAGYAHEGGRAVIICVNKWDEVKGQAAQKKNEFEQQIR
DEFKFLDYAPVVFLSAKSGSNVPKLFRLIKEIYESASKRVTTGELNRFVDHLHFEERKIFYITQHSIRPPAFAVFTDKGP
ALHFSHERYLVNQLRKQFGFKGTPILLQTKAKGKGKPRGK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=460, Percent_Identity=38.0434782608696, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI2367268, Length=95, Percent_Identity=46.3157894736842, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788919, Length=156, Percent_Identity=33.974358974359, Blast_Score=75, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17507259, Length=93, Percent_Identity=39.7849462365591, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=207, Percent_Identity=30.4347826086957, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45550813, Length=93, Percent_Identity=40.8602150537634, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48526; Mature: 48395

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTANPTVVIVGRPNVGKSTLFNRITGQRRAIVGDEPGITRDRLHGAAEHDGRHFELIDT
CCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEECCCCCCCHHHHCCCCCCCCCEEEEEEC
GGIVVHDQEYIPAQILKQAEFALKAADHIIFLVDGRAEITGSDRDLAQMLKKLGKPVSLA
CCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCHHHHHHHHHHCCCCEEH
VNKIDAQVRQDLVNEFYGLGIADVFAISAEHGTGVDAMLDRVTEGFARGEKPTAESTEPK
HHHHHHHHHHHHHHHHHCCCHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
GIKVAIIGRPNVGKSTLLNALTGADRAIVSPIAGTTRDAVDETVSHDGQEYVFVDTAGIR
CEEEEEEECCCCCHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCC
RKGKTHDMAEKLSVVMARRHIRMAHVVLLVLDATEGVVALDTTIAGYAHEGGRAVIICVN
CCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEEECEEECEEECCCCEEEEEEC
KWDEVKGQAAQKKNEFEQQIRDEFKFLDYAPVVFLSAKSGSNVPKLFRLIKEIYESASKR
CCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCC
VTTGELNRFVDHLHFEERKIFYITQHSIRPPAFAVFTDKGPALHFSHERYLVNQLRKQFG
CCHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCCEEEECHHHHHHHHHHHHHC
FKGTPILLQTKAKGKGKPRGK
CCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
STANPTVVIVGRPNVGKSTLFNRITGQRRAIVGDEPGITRDRLHGAAEHDGRHFELIDT
CCCCCEEEEEECCCCCHHHHHHHHCCCCEEEECCCCCCCHHHHCCCCCCCCCEEEEEEC
GGIVVHDQEYIPAQILKQAEFALKAADHIIFLVDGRAEITGSDRDLAQMLKKLGKPVSLA
CCEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCHHHHHHHHHHCCCCEEH
VNKIDAQVRQDLVNEFYGLGIADVFAISAEHGTGVDAMLDRVTEGFARGEKPTAESTEPK
HHHHHHHHHHHHHHHHHCCCHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
GIKVAIIGRPNVGKSTLLNALTGADRAIVSPIAGTTRDAVDETVSHDGQEYVFVDTAGIR
CEEEEEEECCCCCHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCC
RKGKTHDMAEKLSVVMARRHIRMAHVVLLVLDATEGVVALDTTIAGYAHEGGRAVIICVN
CCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEEECEEECEEECCCCEEEEEEC
KWDEVKGQAAQKKNEFEQQIRDEFKFLDYAPVVFLSAKSGSNVPKLFRLIKEIYESASKR
CCHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCC
VTTGELNRFVDHLHFEERKIFYITQHSIRPPAFAVFTDKGPALHFSHERYLVNQLRKQFG
CCHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEEECCCCEEEECHHHHHHHHHHHHHC
FKGTPILLQTKAKGKGKPRGK
CCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA