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The map label for this gene is mmlH [H]

Identifier: 116620125

GI number: 116620125

Start: 1239552

End: 1240829

Strand: Reverse

Name: mmlH [H]

Synonym: Acid_0998

Alternate gene names: 116620125

Gene position: 1240829-1239552 (Counterclockwise)

Preceding gene: 116620129

Following gene: 116620124

Centisome position: 12.45

GC content: 65.65

Gene sequence:

>1278_bases
GTGCCCGAACGCCTCACTACCAATCAGATCCGCGGCTTTTGGGCCGCGTGGGCCGGTTGGGCGCTCGACGGCATGGATTC
CTTCCTCTACGCCCTGGTCCTGGTGCCCGCCCTTCGCGATCTGCTGCCCCGCTCCGGCATCGCCGCCACGCAGGCCAACA
TCGGCTACTACGGCGGAGTGCTCTTCGCCATTTTCCTGCTGGGCTGGGGCTTCGCCTTCCTCTGGGGCCCCCTCGCCGAT
CGCTTCGGCCGTGTTCGCACGCTCGTCCTCACCATCGTCTGCTACTCGCTCTTCACCTTCCTCGGCTCCGCCGCCGCCAA
CGTCTGGCAACTCGCCGCATTCCGCTTTCTCGCCGGCATCGGCATCGGCGGTGAATGGACCATCGGCGGAGTCTTCGTCG
CCGAGGAATGGCCCGAATCCCGCCGAAAGAATGGCGCTGCCTGGATGCACACCGGCTACTACTTCGGCACCTTCCTCGCC
GCCATCGTCAATTACACCGTGGGCTCGCACTATGGCTGGCGCGCCGTCTTCGCCGTCGGCGGCACTCCGGCCCTGCTCGT
CGCCTTCATTCGCTACGGCGTTCGCGAATCCAAGCGCTGGGAGCAAGGCGTCGCAAAACGCCAAGATCGCTGGACCGCCC
GCGACGCCTTCTTTGCCCTCTTCTCCGCCGAGTACCGCAATCGGACTGTCGTCAACGCCGCGCTGCTCTTCATCTCCATG
GTCGGCCTCTGGGCCGGCTCCGCTTACGTGCCGTCCTCCATCACCTACCTGGCGGTACACGAAGGCTTTACGGCCGCCGA
TGCCGCGCGTCTTGCATCATGGGCCATCATGCTGCTTTCCGCCGGCACAATCCTAGGCTGCCTCATGCTGCCCGCGCTTG
CCGAGCGCCTCGGCCGCCGCGGAGCCCTCGCCTTCTACTTCCTGCTGATGTTTCTCTGCATCGCGCTCGGCTTCGGCTGG
GTCTTTTACCGCGCGGCGAACGCGCTTCCCTGGTTTATGGCCTGCCTCTTCTTCCTCGGCATCGGCGGCGCCAATTTCTC
GGTCTACACCCTGTGGCTGCCGGAGCAATACCGCACGGAATGCCGCGGCAGCGCCTTCGCCTTCGCCACTTCATTCGGCC
GCTTCCTCGCCGCCGGGATCACTTTCCTGGTTGGCGCCGGAGTCGCCCGCATGCACACCATCGGCACTCCGGTCGCACTG
ACTTGCATCGCCTTCCTGGTCGGACTGGCGCTGTTACCGCTCGCCGTGGAAACTAAAGGCAAGGAGCTGCCCGCGTGA

Upstream 100 bases:

>100_bases
ACGTGGACTTGCCCGATCCCGGCAGCCCCACCAGCACCACAATGCGCATTCAGCAATCAGGATAGCGAAGTCCGCCGGTG
GACCTGCTACCGTATTCTGA

Downstream 100 bases:

>100_bases
ACCTCACGCATCTCTTCGATCTCTCCCTGTCCGGCCGCCGCGACACCGGCGCGCTCGAATTCCAGGACCGCTGCTACACG
TTCGGCGAACTGGATTCACG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MPERLTTNQIRGFWAAWAGWALDGMDSFLYALVLVPALRDLLPRSGIAATQANIGYYGGVLFAIFLLGWGFAFLWGPLAD
RFGRVRTLVLTIVCYSLFTFLGSAAANVWQLAAFRFLAGIGIGGEWTIGGVFVAEEWPESRRKNGAAWMHTGYYFGTFLA
AIVNYTVGSHYGWRAVFAVGGTPALLVAFIRYGVRESKRWEQGVAKRQDRWTARDAFFALFSAEYRNRTVVNAALLFISM
VGLWAGSAYVPSSITYLAVHEGFTAADAARLASWAIMLLSAGTILGCLMLPALAERLGRRGALAFYFLLMFLCIALGFGW
VFYRAANALPWFMACLFFLGIGGANFSVYTLWLPEQYRTECRGSAFAFATSFGRFLAAGITFLVGAGVARMHTIGTPVAL
TCIAFLVGLALLPLAVETKGKELPA

Sequences:

>Translated_425_residues
MPERLTTNQIRGFWAAWAGWALDGMDSFLYALVLVPALRDLLPRSGIAATQANIGYYGGVLFAIFLLGWGFAFLWGPLAD
RFGRVRTLVLTIVCYSLFTFLGSAAANVWQLAAFRFLAGIGIGGEWTIGGVFVAEEWPESRRKNGAAWMHTGYYFGTFLA
AIVNYTVGSHYGWRAVFAVGGTPALLVAFIRYGVRESKRWEQGVAKRQDRWTARDAFFALFSAEYRNRTVVNAALLFISM
VGLWAGSAYVPSSITYLAVHEGFTAADAARLASWAIMLLSAGTILGCLMLPALAERLGRRGALAFYFLLMFLCIALGFGW
VFYRAANALPWFMACLFFLGIGGANFSVYTLWLPEQYRTECRGSAFAFATSFGRFLAAGITFLVGAGVARMHTIGTPVAL
TCIAFLVGLALLPLAVETKGKELPA
>Mature_424_residues
PERLTTNQIRGFWAAWAGWALDGMDSFLYALVLVPALRDLLPRSGIAATQANIGYYGGVLFAIFLLGWGFAFLWGPLADR
FGRVRTLVLTIVCYSLFTFLGSAAANVWQLAAFRFLAGIGIGGEWTIGGVFVAEEWPESRRKNGAAWMHTGYYFGTFLAA
IVNYTVGSHYGWRAVFAVGGTPALLVAFIRYGVRESKRWEQGVAKRQDRWTARDAFFALFSAEYRNRTVVNAALLFISMV
GLWAGSAYVPSSITYLAVHEGFTAADAARLASWAIMLLSAGTILGCLMLPALAERLGRRGALAFYFLLMFLCIALGFGWV
FYRAANALPWFMACLFFLGIGGANFSVYTLWLPEQYRTECRGSAFAFATSFGRFLAAGITFLVGAGVARMHTIGTPVALT
CIAFLVGLALLPLAVETKGKELPA

Specific function: Probable uptake of 4-methylmuconolactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=313, Percent_Identity=26.8370607028754, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87082231, Length=229, Percent_Identity=28.82096069869, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790550, Length=334, Percent_Identity=25.4491017964072, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081723, Length=326, Percent_Identity=26.6871165644172, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46443; Mature: 46312

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPERLTTNQIRGFWAAWAGWALDGMDSFLYALVLVPALRDLLPRSGIAATQANIGYYGGV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHH
LFAIFLLGWGFAFLWGPLADRFGRVRTLVLTIVCYSLFTFLGSAAANVWQLAAFRFLAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIGGEWTIGGVFVAEEWPESRRKNGAAWMHTGYYFGTFLAAIVNYTVGSHYGWRAVFAVG
CCCCCEEECCEEEECCCCHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
GTPALLVAFIRYGVRESKRWEQGVAKRQDRWTARDAFFALFSAEYRNRTVVNAALLFISM
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VGLWAGSAYVPSSITYLAVHEGFTAADAARLASWAIMLLSAGTILGCLMLPALAERLGRR
HHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GALAFYFLLMFLCIALGFGWVFYRAANALPWFMACLFFLGIGGANFSVYTLWLPEQYRTE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCHHHHHH
CRGSAFAFATSFGRFLAAGITFLVGAGVARMHTIGTPVALTCIAFLVGLALLPLAVETKG
HCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
KELPA
CCCCC
>Mature Secondary Structure 
PERLTTNQIRGFWAAWAGWALDGMDSFLYALVLVPALRDLLPRSGIAATQANIGYYGGV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHH
LFAIFLLGWGFAFLWGPLADRFGRVRTLVLTIVCYSLFTFLGSAAANVWQLAAFRFLAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIGGEWTIGGVFVAEEWPESRRKNGAAWMHTGYYFGTFLAAIVNYTVGSHYGWRAVFAVG
CCCCCEEECCEEEECCCCHHHHCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCEEEEEEC
GTPALLVAFIRYGVRESKRWEQGVAKRQDRWTARDAFFALFSAEYRNRTVVNAALLFISM
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VGLWAGSAYVPSSITYLAVHEGFTAADAARLASWAIMLLSAGTILGCLMLPALAERLGRR
HHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GALAFYFLLMFLCIALGFGWVFYRAANALPWFMACLFFLGIGGANFSVYTLWLPEQYRTE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEEECCHHHHHH
CRGSAFAFATSFGRFLAAGITFLVGAGVARMHTIGTPVALTCIAFLVGLALLPLAVETKG
HCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
KELPA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9461415 [H]