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The map label for this gene is cspLA [H]

Identifier: 116620045

GI number: 116620045

Start: 1146870

End: 1147073

Strand: Reverse

Name: cspLA [H]

Synonym: Acid_0917

Alternate gene names: 116620045

Gene position: 1147073-1146870 (Counterclockwise)

Preceding gene: 116620048

Following gene: 116620039

Centisome position: 11.51

GC content: 56.37

Gene sequence:

>204_bases
ATGAGAGAAACAGGTACAGTAAAGTGGTTCAACGCCGGGAAGGGATTCGGCTTTATCCAGCGTGAGAATGGCGAGGACGT
CTTCGTTCATTTCTCCGCCATCTCGGCGAGCGGCTATCGTTCGCTCGATGAAGGCGCACGCGTCTCCTTCGTGGTGAAGA
AGGGCCCGAAGGGCCTGCAAGCCGAAGATGTTAGCCCGGCATAA

Upstream 100 bases:

>100_bases
TTTGAATCTGCTGAATGTGGTCCAGTGCTTTGTTGTCACGTCGGAAGCATCATCCTCAATCGATAGGTCAGGAGTCTAGA
GATCGGAAGAAAGAGGAAAG

Downstream 100 bases:

>100_bases
GCCGGCACAATTCATTTGAAACATCGGAGAGGCGCTGCCTGCGGGCAGCGCCTCTTTTCATTTGTAGGCACGATCACACG
AATCTGTGCGTGCGTGCTCC

Product: cold-shock DNA-binding protein family protein

Products: NA

Alternate protein names: CspL [H]

Number of amino acids: Translated: 67; Mature: 67

Protein sequence:

>67_residues
MRETGTVKWFNAGKGFGFIQRENGEDVFVHFSAISASGYRSLDEGARVSFVVKKGPKGLQAEDVSPA

Sequences:

>Translated_67_residues
MRETGTVKWFNAGKGFGFIQRENGEDVFVHFSAISASGYRSLDEGARVSFVVKKGPKGLQAEDVSPA
>Mature_67_residues
MRETGTVKWFNAGKGFGFIQRENGEDVFVHFSAISASGYRSLDEGARVSFVVKKGPKGLQAEDVSPA

Specific function: Binds To And Stimulates The Transcription Of The CCAAT- Containing, Cold-Shock-Inducible Promoters Of The H-Ns And Gyra Proteins. Binds Also To The Inverted Repeat 5'-ATTGG-3'. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Escherichia coli, GI1789979, Length=65, Percent_Identity=60, Blast_Score=79, Evalue=5e-17,
Organism=Escherichia coli, GI1787107, Length=65, Percent_Identity=55.3846153846154, Blast_Score=72, Evalue=5e-15,
Organism=Escherichia coli, GI1787839, Length=64, Percent_Identity=56.25, Blast_Score=70, Evalue=2e-14,
Organism=Escherichia coli, GI1786841, Length=61, Percent_Identity=57.3770491803279, Blast_Score=70, Evalue=2e-14,
Organism=Escherichia coli, GI2367114, Length=64, Percent_Identity=50, Blast_Score=69, Evalue=7e-14,
Organism=Escherichia coli, GI1787834, Length=64, Percent_Identity=51.5625, Blast_Score=66, Evalue=4e-13,
Organism=Escherichia coli, GI1788126, Length=62, Percent_Identity=53.2258064516129, Blast_Score=65, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71983217, Length=55, Percent_Identity=49.0909090909091, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 7265; Mature: 7265

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS00352 COLD_SHOCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRETGTVKWFNAGKGFGFIQRENGEDVFVHFSAISASGYRSLDEGARVSFVVKKGPKGLQ
CCCCCCEEEEECCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCC
AEDVSPA
CCCCCCC
>Mature Secondary Structure
MRETGTVKWFNAGKGFGFIQRENGEDVFVHFSAISASGYRSLDEGARVSFVVKKGPKGLQ
CCCCCCEEEEECCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCC
AEDVSPA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669; 9439003 [H]