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The map label for this gene is blaR1 [H]

Identifier: 116620027

GI number: 116620027

Start: 1128540

End: 1130387

Strand: Direct

Name: blaR1 [H]

Synonym: Acid_0899

Alternate gene names: 116620027

Gene position: 1128540-1130387 (Clockwise)

Preceding gene: 116620026

Following gene: 116620028

Centisome position: 11.32

GC content: 65.1

Gene sequence:

>1848_bases
ATGAACCTGATTCAGAACTGGGTAGAAACTCCGGCCGCGACCGCGCTGGGGTGGACGCTGATTCATTCCCTGTGGGAGGG
CGCGGTTGTCGCGCTGCTGCTCGCCGCAGCGCTGTGCGTGTTGCGGGGCGCGCGCGCGCGATACGCCGCGGGCTGTCTCG
CGCTGCTGGTCCTGCTAGCCGGTTTTGGGTTCACGTTCGCGAGGCTGCTGGCTGCTCAGGGGAGCCTGGACGCTGCCACG
CGGATCGGGCCGCTGCGATTTGCGCCGCTCGACGCGGATGCCGGGAGTCTGTCCGCCATGCGGAGTGCGGGAGGGTTGGC
GGAGTATCTTCCGTGGATCGCGCCGTTCTGGGTCGCCGGCGTATTGATCTTCCACCTTCGAAGTTTGATGGGGTGGCTGG
GTGCCCGGCGGCTGCGGCGCACCGGTGTCTGTTGCGCGCCGGCGATGTGGCAGCAAATGCTCGAGCGGCTGGCCGCGCGG
CTGCGGATTTCGCGGCCGGTGACGCTTTGGGAGTCCTGCCTGGCCGATGTGCCGCTCGTGATCGGCTTCCTGCGTCCGGT
GATTCTGATCCCGGTGGGGATGCTTGCCGGCGTGCCGGCGGCGCAGGTGGAGGCGCTGCTGCTGCACGAGCTGGCGCACA
TCCGCCGCCACGATTACCTGGTGAACCTGCTGCAGGTCTTTGTGGAAGGTCTGCTCTTTTACCATCCCGCTGTCTGGTGG
ATGGCCTCGGCGATTCGCGCCGAGCGCGAACACTGCTGCGATGATCTGGTAGTCGCCACGCAGGGCGACGCTTACCTGTA
CGCCAGTGCGCTCGCCGCACTGGAACATAACCGCGGAGATGCGCGCCAGCCCGCGCTCGCCGCTAACGGAGGAAGTCTCG
TGAAACGTATTCGCCGTCTGTTGATTCAACCGGAGACTTCGCGCTCCGGTCTTGCGCCGGTACTTTCCGCCGCCATATTG
ACCGTCACGGTGGCGGCGGCGCTGGCGGCATGGCAGACTAAGCCGCCGGCTCCGCCTGCTCCGCCCGCACCCGCTCCCGC
GGAATCACCCGCGCCGCCGCCACTGCCGCCTGCTCCGCCCGCACCCGCTCCCGCGGAAGCACCCGCGCCGCCGCCGCCGG
TGGAAACTCCGTACGCAAAGTGGGTCAAGGAAGATGTCGCCTACATCATCACCGACGCCGAGCGCGCCGCATTCAAGCGC
CTGCCGACCGACGAGGAGCGCGAGCACTTCATCGAACAGTTCTGGCAGCGCCGCGACCCGACTCCCGGCACTCCGGTCAA
CGAATTCAAGGCAGAACACTATCGACGCATCGCGTACGCCAATAACAACTTTTCGTCCTCGATCGCGGGTTGGAAAACCG
ATCGCGGCCGCGTCTACATCACCTACGGACCGTCCGATGAGAAAGAGACCCACCCCACCGGCGGCTCGTCGTATTCCTAT
CCTTACGAGCAGTGGATGTACCACTTCATCGACGGGGTGGGGAAGAACATCATCGTCGAGTTTGTCGATCCGGACCGGAC
GGGCGAATATCGGATGACGAGCGACCCGAATGCCGCCCTGGTCACGCTGCCGGCTTCTTCTGTGACGGGGGTGACGGCCG
TGCAGGTGCTTGGCGGCAAGGCGATGATCTCGATTTTGCCGCGGGGGTCTCAGCGCCTCATCATACTCGGTCGAATTCTG
AACAAAGAAGGCGCACAGGTGACGGCTTTCGAAGATACCGCGCAGGGGCCGCAGCAATATGTCAAGAGTGTTCCCTTGTC
GCTGGGCGAGTACCGGTTGGTGACCGTGGTGAAGGATTTGGCGACCGGGCGGTCAAGCGAGACAACCACTAGCTTCAGCG
TGAAGTAG

Upstream 100 bases:

>100_bases
CGCGCACGCTCATGATGGGGGCGCTGTCGGCGCACAAGGCGTCGAAAAAAGAACTGGCGGAGCTGCGCAAGCTGCTCGAG
GAATACGAAAAGGGGGCGAG

Downstream 100 bases:

>100_bases
CTTGCAATCGTGGGGCGCACGTGGTAAACATTAAGGGAGCTTAATCTTTCCCGTGCGCCGATTCTCTCCAATCCGCAGTT
GTGCCGCATTGATGGTCGTA

Product: peptidase M56, BlaR1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MNLIQNWVETPAATALGWTLIHSLWEGAVVALLLAAALCVLRGARARYAAGCLALLVLLAGFGFTFARLLAAQGSLDAAT
RIGPLRFAPLDADAGSLSAMRSAGGLAEYLPWIAPFWVAGVLIFHLRSLMGWLGARRLRRTGVCCAPAMWQQMLERLAAR
LRISRPVTLWESCLADVPLVIGFLRPVILIPVGMLAGVPAAQVEALLLHELAHIRRHDYLVNLLQVFVEGLLFYHPAVWW
MASAIRAEREHCCDDLVVATQGDAYLYASALAALEHNRGDARQPALAANGGSLVKRIRRLLIQPETSRSGLAPVLSAAIL
TVTVAAALAAWQTKPPAPPAPPAPAPAESPAPPPLPPAPPAPAPAEAPAPPPPVETPYAKWVKEDVAYIITDAERAAFKR
LPTDEEREHFIEQFWQRRDPTPGTPVNEFKAEHYRRIAYANNNFSSSIAGWKTDRGRVYITYGPSDEKETHPTGGSSYSY
PYEQWMYHFIDGVGKNIIVEFVDPDRTGEYRMTSDPNAALVTLPASSVTGVTAVQVLGGKAMISILPRGSQRLIILGRIL
NKEGAQVTAFEDTAQGPQQYVKSVPLSLGEYRLVTVVKDLATGRSSETTTSFSVK

Sequences:

>Translated_615_residues
MNLIQNWVETPAATALGWTLIHSLWEGAVVALLLAAALCVLRGARARYAAGCLALLVLLAGFGFTFARLLAAQGSLDAAT
RIGPLRFAPLDADAGSLSAMRSAGGLAEYLPWIAPFWVAGVLIFHLRSLMGWLGARRLRRTGVCCAPAMWQQMLERLAAR
LRISRPVTLWESCLADVPLVIGFLRPVILIPVGMLAGVPAAQVEALLLHELAHIRRHDYLVNLLQVFVEGLLFYHPAVWW
MASAIRAEREHCCDDLVVATQGDAYLYASALAALEHNRGDARQPALAANGGSLVKRIRRLLIQPETSRSGLAPVLSAAIL
TVTVAAALAAWQTKPPAPPAPPAPAPAESPAPPPLPPAPPAPAPAEAPAPPPPVETPYAKWVKEDVAYIITDAERAAFKR
LPTDEEREHFIEQFWQRRDPTPGTPVNEFKAEHYRRIAYANNNFSSSIAGWKTDRGRVYITYGPSDEKETHPTGGSSYSY
PYEQWMYHFIDGVGKNIIVEFVDPDRTGEYRMTSDPNAALVTLPASSVTGVTAVQVLGGKAMISILPRGSQRLIILGRIL
NKEGAQVTAFEDTAQGPQQYVKSVPLSLGEYRLVTVVKDLATGRSSETTTSFSVK
>Mature_615_residues
MNLIQNWVETPAATALGWTLIHSLWEGAVVALLLAAALCVLRGARARYAAGCLALLVLLAGFGFTFARLLAAQGSLDAAT
RIGPLRFAPLDADAGSLSAMRSAGGLAEYLPWIAPFWVAGVLIFHLRSLMGWLGARRLRRTGVCCAPAMWQQMLERLAAR
LRISRPVTLWESCLADVPLVIGFLRPVILIPVGMLAGVPAAQVEALLLHELAHIRRHDYLVNLLQVFVEGLLFYHPAVWW
MASAIRAEREHCCDDLVVATQGDAYLYASALAALEHNRGDARQPALAANGGSLVKRIRRLLIQPETSRSGLAPVLSAAIL
TVTVAAALAAWQTKPPAPPAPPAPAPAESPAPPPLPPAPPAPAPAEAPAPPPPVETPYAKWVKEDVAYIITDAERAAFKR
LPTDEEREHFIEQFWQRRDPTPGTPVNEFKAEHYRRIAYANNNFSSSIAGWKTDRGRVYITYGPSDEKETHPTGGSSYSY
PYEQWMYHFIDGVGKNIIVEFVDPDRTGEYRMTSDPNAALVTLPASSVTGVTAVQVLGGKAMISILPRGSQRLIILGRIL
NKEGAQVTAFEDTAQGPQQYVKSVPLSLGEYRLVTVVKDLATGRSSETTTSFSVK

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG4219

COG function: function code KT; Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 66708; Mature: 66708

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIQNWVETPAATALGWTLIHSLWEGAVVALLLAAALCVLRGARARYAAGCLALLVLLA
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GFGFTFARLLAAQGSLDAATRIGPLRFAPLDADAGSLSAMRSAGGLAEYLPWIAPFWVAG
HHHHHHHHHHHHCCCCHHHHHCCCEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
VLIFHLRSLMGWLGARRLRRTGVCCAPAMWQQMLERLAARLRISRPVTLWESCLADVPLV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IGFLRPVILIPVGMLAGVPAAQVEALLLHELAHIRRHDYLVNLLQVFVEGLLFYHPAVWW
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MASAIRAEREHCCDDLVVATQGDAYLYASALAALEHNRGDARQPALAANGGSLVKRIRRL
HHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
LIQPETSRSGLAPVLSAAILTVTVAAALAAWQTKPPAPPAPPAPAPAESPAPPPLPPAPP
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APAPAEAPAPPPPVETPYAKWVKEDVAYIITDAERAAFKRLPTDEEREHFIEQFWQRRDP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECHHHHHHHCCCCCHHHHHHHHHHHHCCCC
TPGTPVNEFKAEHYRRIAYANNNFSSSIAGWKTDRGRVYITYGPSDEKETHPTGGSSYSY
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC
PYEQWMYHFIDGVGKNIIVEFVDPDRTGEYRMTSDPNAALVTLPASSVTGVTAVQVLGGK
CHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCCEEEEECCCCCCHHHHHHHHCCC
AMISILPRGSQRLIILGRILNKEGAQVTAFEDTAQGPQQYVKSVPLSLGEYRLVTVVKDL
CEEEECCCCCCEEEEEEEHHCCCCCEEEEECHHCCCHHHHHHHCCCCCCCHHHHHHHHHH
ATGRSSETTTSFSVK
HCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLIQNWVETPAATALGWTLIHSLWEGAVVALLLAAALCVLRGARARYAAGCLALLVLLA
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GFGFTFARLLAAQGSLDAATRIGPLRFAPLDADAGSLSAMRSAGGLAEYLPWIAPFWVAG
HHHHHHHHHHHHCCCCHHHHHCCCEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
VLIFHLRSLMGWLGARRLRRTGVCCAPAMWQQMLERLAARLRISRPVTLWESCLADVPLV
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IGFLRPVILIPVGMLAGVPAAQVEALLLHELAHIRRHDYLVNLLQVFVEGLLFYHPAVWW
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MASAIRAEREHCCDDLVVATQGDAYLYASALAALEHNRGDARQPALAANGGSLVKRIRRL
HHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
LIQPETSRSGLAPVLSAAILTVTVAAALAAWQTKPPAPPAPPAPAPAESPAPPPLPPAPP
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
APAPAEAPAPPPPVETPYAKWVKEDVAYIITDAERAAFKRLPTDEEREHFIEQFWQRRDP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECHHHHHHHCCCCCHHHHHHHHHHHHCCCC
TPGTPVNEFKAEHYRRIAYANNNFSSSIAGWKTDRGRVYITYGPSDEKETHPTGGSSYSY
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC
PYEQWMYHFIDGVGKNIIVEFVDPDRTGEYRMTSDPNAALVTLPASSVTGVTAVQVLGGK
CHHHHHHHHHHCCCCCEEEEEECCCCCCCEEECCCCCCEEEEECCCCCCHHHHHHHHCCC
AMISILPRGSQRLIILGRILNKEGAQVTAFEDTAQGPQQYVKSVPLSLGEYRLVTVVKDL
CEEEECCCCCCEEEEEEEHHCCCCCEEEEECHHCCCHHHHHHHCCCCCCCHHHHHHHHHH
ATGRSSETTTSFSVK
HCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]