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The map label for this gene is prsA [H]

Identifier: 116620016

GI number: 116620016

Start: 1119826

End: 1120767

Strand: Reverse

Name: prsA [H]

Synonym: Acid_0888

Alternate gene names: 116620016

Gene position: 1120767-1119826 (Counterclockwise)

Preceding gene: 116620017

Following gene: 116620015

Centisome position: 11.25

GC content: 60.51

Gene sequence:

>942_bases
ATGAAAGCTTCTTCTCTCTGCATACTCTTCCTTTGCCTCGGCGCTGCTTGGGCACAAACCGCTGCCCCTCCGCCGGCCAC
CCTCCCTGACGTGCCCGACGACACGGTGATCGCCATCTTCGGCGACGGCACCAAGCTCACTATGGCCGAATTCAAGCGCA
TCTATAACGCCCTCCCCCCGGCCAACCAACAGATGGCGCTCCGCGATCGCGCCCAATGGCTGCATCAATGGGAAATGATG
CGCAAACTCACCAAGATGGCCGAGCAGGCGAAGCTCGACCAGGAGAGCCCTTACAAAGAAGCCATCGATTATGGACGCAT
GAACGTGCTGGCCACGGCCCAGATCACCGCCACCGTCAATGCGATGACCGTCGAACCCGCCGAGATCGTCAAGAGCTACG
ATTCCAACAAGCAGAAATACACCCAGGTCAAGGTCAAGGCCATCTACGTCGCCTTCAGCGACGATGCCGCCGCCTCCACC
ACCAAGGGGAAGAAGCCGCTTACCGAAGCCGAAGCCAAAGCCAAGGTCGAGAAACTCAAAGCCGCGCTGAAAGGCGGCGC
CGATTTCGTGAAACTGGTGAAGGAAAACTCGGACGACGAGACTTCCCGCGAAAAAGGCGGCGACTTCGCCACCCTGCGCT
ATACCGACAACATCCCCGACGCCTTCCGCGCCGCCGTTTTTGCCCTCAAGAAGGGCGATGTCAGCGAACCACTCAAGCAG
CCCAACGGGTTCTACCTCCTGCGCGCCGAGGAAGTTACCGTCAGCCCCCTCTCCGAGGTCCGCGACGATATCTACAACCA
GCTGAAGAACGACCGCGCCACCCAATGGCTGGACCAGGTCAATCGCGATTCCAAGGTTCAGATCATGAGCCAGGAATTCG
TCGGACACCCGGCGGCGCCCCCGGCTCCCCCGAAAGCTCCGGCCGCTCCGCCCAAAAAGTAG

Upstream 100 bases:

>100_bases
AAGCCGCAAAGTAACGCAAAGAAAACAAAACCTTTAAACAGAGATTGGCTTCGTTCTCGAATGCCGCTTCACCCGTGATA
AAATAGCTCAAGCAATCCCC

Downstream 100 bases:

>100_bases
TACCCGCAAAACCCAGTCACACGAACTTGGAATTTATAATCGCCTTGATTTGAGTCACTTGGTTCCTGGAGGGCCTTGCG
CTCGAGGCTCGTCTCCTAGT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKASSLCILFLCLGAAWAQTAAPPPATLPDVPDDTVIAIFGDGTKLTMAEFKRIYNALPPANQQMALRDRAQWLHQWEMM
RKLTKMAEQAKLDQESPYKEAIDYGRMNVLATAQITATVNAMTVEPAEIVKSYDSNKQKYTQVKVKAIYVAFSDDAAAST
TKGKKPLTEAEAKAKVEKLKAALKGGADFVKLVKENSDDETSREKGGDFATLRYTDNIPDAFRAAVFALKKGDVSEPLKQ
PNGFYLLRAEEVTVSPLSEVRDDIYNQLKNDRATQWLDQVNRDSKVQIMSQEFVGHPAAPPAPPKAPAAPPKK

Sequences:

>Translated_313_residues
MKASSLCILFLCLGAAWAQTAAPPPATLPDVPDDTVIAIFGDGTKLTMAEFKRIYNALPPANQQMALRDRAQWLHQWEMM
RKLTKMAEQAKLDQESPYKEAIDYGRMNVLATAQITATVNAMTVEPAEIVKSYDSNKQKYTQVKVKAIYVAFSDDAAAST
TKGKKPLTEAEAKAKVEKLKAALKGGADFVKLVKENSDDETSREKGGDFATLRYTDNIPDAFRAAVFALKKGDVSEPLKQ
PNGFYLLRAEEVTVSPLSEVRDDIYNQLKNDRATQWLDQVNRDSKVQIMSQEFVGHPAAPPAPPKAPAAPPKK
>Mature_313_residues
MKASSLCILFLCLGAAWAQTAAPPPATLPDVPDDTVIAIFGDGTKLTMAEFKRIYNALPPANQQMALRDRAQWLHQWEMM
RKLTKMAEQAKLDQESPYKEAIDYGRMNVLATAQITATVNAMTVEPAEIVKSYDSNKQKYTQVKVKAIYVAFSDDAAAST
TKGKKPLTEAEAKAKVEKLKAALKGGADFVKLVKENSDDETSREKGGDFATLRYTDNIPDAFRAAVFALKKGDVSEPLKQ
PNGFYLLRAEEVTVSPLSEVRDDIYNQLKNDRATQWLDQVNRDSKVQIMSQEFVGHPAAPPAPPKAPAAPPKK

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 34477; Mature: 34477

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKASSLCILFLCLGAAWAQTAAPPPATLPDVPDDTVIAIFGDGTKLTMAEFKRIYNALPP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCC
ANQQMALRDRAQWLHQWEMMRKLTKMAEQAKLDQESPYKEAIDYGRMNVLATAQITATVN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEEEEEEEEEE
AMTVEPAEIVKSYDSNKQKYTQVKVKAIYVAFSDDAAASTTKGKKPLTEAEAKAKVEKLK
EEEECHHHHHHHHCCCCHHHHEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
AALKGGADFVKLVKENSDDETSREKGGDFATLRYTDNIPDAFRAAVFALKKGDVSEPLKQ
HHHHCCHHHHHHHHCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHC
PNGFYLLRAEEVTVSPLSEVRDDIYNQLKNDRATQWLDQVNRDSKVQIMSQEFVGHPAAP
CCCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEHHHHHCCCCCCC
PAPPKAPAAPPKK
CCCCCCCCCCCCC
>Mature Secondary Structure
MKASSLCILFLCLGAAWAQTAAPPPATLPDVPDDTVIAIFGDGTKLTMAEFKRIYNALPP
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHCCCC
ANQQMALRDRAQWLHQWEMMRKLTKMAEQAKLDQESPYKEAIDYGRMNVLATAQITATVN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEEEEEEEEEE
AMTVEPAEIVKSYDSNKQKYTQVKVKAIYVAFSDDAAASTTKGKKPLTEAEAKAKVEKLK
EEEECHHHHHHHHCCCCHHHHEEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHH
AALKGGADFVKLVKENSDDETSREKGGDFATLRYTDNIPDAFRAAVFALKKGDVSEPLKQ
HHHHCCHHHHHHHHCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHC
PNGFYLLRAEEVTVSPLSEVRDDIYNQLKNDRATQWLDQVNRDSKVQIMSQEFVGHPAAP
CCCEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEHHHHHCCCCCCC
PAPPKAPAAPPKK
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA