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The map label for this gene is dinB [H]

Identifier: 116619978

GI number: 116619978

Start: 1053551

End: 1054795

Strand: Reverse

Name: dinB [H]

Synonym: Acid_0850

Alternate gene names: 116619978

Gene position: 1054795-1053551 (Counterclockwise)

Preceding gene: 116619981

Following gene: 116619975

Centisome position: 10.58

GC content: 64.34

Gene sequence:

>1245_bases
GTGCGCACTTACTTCCACGTCGATATGGACGCGTTCTTTGTGTCCGTGGAAGAGCTGTTCGATCCCTCACTGAAGGGCAA
GCCGGTCGTGGTCGGCGGGCAGTCGAACGAACGTGGCGTGGTGTCGGCGGCCTCCTACGCGGCGCGCAAATTCGGCGTGC
ATTCCGCGATGCCGCTGCGGACGGCGTACAAATTGTGCCCGCAGGCGATCTTCGTGGACGGTCATCCCGACCGCTATCGT
GAGTACTCCCACAGGGTGCACGAGGTGCTGGAGAGCTTTTCACCGCTGGTGGAGATGGCCTCGGTGGATGAAGCGTACCT
CGATATCACGGGCACGGAGCGGCTTTACGGGCCGCCGCTGCGGGCCGCGCACCTGCTGCACGAGCGCATGAAGGCGGCGA
CAAAATTGAACTGCTCCATCGGGATCGCGGCATCGCGGCTGGTGGCGAAGATCACGTCTGACCAGGCCAAGCCGAACGGG
ATCATGTGGATTCTTGCAGGGCGCGAGGCGGCGTTTCTGGCCCCCCTCGACGTCCGCAAGATCCCGGGAGTCGGCAAGGT
GACGGAGAAGAATCTGCACCTGCTCGGGATTCGCAAGGTCGGCGACCTGGCGCGGCTGGACGACGCCTTTCTCGAAGAGC
GTTTCGGCAAGTGGGGTATGGCGCTGGCCGGAAAATCGCGCGGGCTCGACGCGGGCGGGTGGTTCGATACCGAGATCGGC
GAAGAGCAGGGTCCGAAATCGATCAGCCATGAGCACACGTTCAACGAAGACACCGCCGATCTGGGGCAGATCGAATCGAC
GCTGGCGCGGTTGTCGGAGATGGTGGGACGGCGCTTGCGCGAGCAGGCGCTGGAGGCGCGGACGCTGCAGTTGAAGCTGC
GCTACTCGGATTTCTCGACGATCACGCGTGCGCATTCGCTACCCCGAGCGACACAACTCGATACCGAGATCTATGAAGAG
ATCCGCGAGCTCTTTCGCCGCAATTGGAAGAGGGGCGCAACCGTCCGGCTGCTCGGCGTGCACGCCTCGGGGTGGGCCGA
CGGCGACGAGCAGATGCACTTGCTCGGCGAGGACCGTCACCAGAAGTGGAAGGAGACGCTGGCTGCCGCCGACCGCATGC
GCGATCGCTTCGGCGAAAAGGCCGTCTCGCTGGCCGCCAGCCTGCGCGGCAATTTCAAGGAGCGCACGCACGAAAACCCT
GTGGGCCTGCCAGGGAAGAAGCCGTCACCGAACCGCGACCCTTAG

Upstream 100 bases:

>100_bases
GGCGGCAGCGCCGGCGATCGCCAGCACGATCGCCCAAGTACGATGCGACATTCCCCAACTATAACGTAGTTGCGGCCGCG
GCTCGGTTAACATGGGAGAA

Downstream 100 bases:

>100_bases
GCAGCGGTCTCTTGGGTCCTACTTCTTCTTCCGGCGCCAGGTAAGGAAGCCGATGAGGGTCTTGCCGTCTTCAATTTTGC
CTTCATCGATCATCTCGGCG

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MRTYFHVDMDAFFVSVEELFDPSLKGKPVVVGGQSNERGVVSAASYAARKFGVHSAMPLRTAYKLCPQAIFVDGHPDRYR
EYSHRVHEVLESFSPLVEMASVDEAYLDITGTERLYGPPLRAAHLLHERMKAATKLNCSIGIAASRLVAKITSDQAKPNG
IMWILAGREAAFLAPLDVRKIPGVGKVTEKNLHLLGIRKVGDLARLDDAFLEERFGKWGMALAGKSRGLDAGGWFDTEIG
EEQGPKSISHEHTFNEDTADLGQIESTLARLSEMVGRRLREQALEARTLQLKLRYSDFSTITRAHSLPRATQLDTEIYEE
IRELFRRNWKRGATVRLLGVHASGWADGDEQMHLLGEDRHQKWKETLAAADRMRDRFGEKAVSLAASLRGNFKERTHENP
VGLPGKKPSPNRDP

Sequences:

>Translated_414_residues
MRTYFHVDMDAFFVSVEELFDPSLKGKPVVVGGQSNERGVVSAASYAARKFGVHSAMPLRTAYKLCPQAIFVDGHPDRYR
EYSHRVHEVLESFSPLVEMASVDEAYLDITGTERLYGPPLRAAHLLHERMKAATKLNCSIGIAASRLVAKITSDQAKPNG
IMWILAGREAAFLAPLDVRKIPGVGKVTEKNLHLLGIRKVGDLARLDDAFLEERFGKWGMALAGKSRGLDAGGWFDTEIG
EEQGPKSISHEHTFNEDTADLGQIESTLARLSEMVGRRLREQALEARTLQLKLRYSDFSTITRAHSLPRATQLDTEIYEE
IRELFRRNWKRGATVRLLGVHASGWADGDEQMHLLGEDRHQKWKETLAAADRMRDRFGEKAVSLAASLRGNFKERTHENP
VGLPGKKPSPNRDP
>Mature_414_residues
MRTYFHVDMDAFFVSVEELFDPSLKGKPVVVGGQSNERGVVSAASYAARKFGVHSAMPLRTAYKLCPQAIFVDGHPDRYR
EYSHRVHEVLESFSPLVEMASVDEAYLDITGTERLYGPPLRAAHLLHERMKAATKLNCSIGIAASRLVAKITSDQAKPNG
IMWILAGREAAFLAPLDVRKIPGVGKVTEKNLHLLGIRKVGDLARLDDAFLEERFGKWGMALAGKSRGLDAGGWFDTEIG
EEQGPKSISHEHTFNEDTADLGQIESTLARLSEMVGRRLREQALEARTLQLKLRYSDFSTITRAHSLPRATQLDTEIYEE
IRELFRRNWKRGATVRLLGVHASGWADGDEQMHLLGEDRHQKWKETLAAADRMRDRFGEKAVSLAASLRGNFKERTHENP
VGLPGKKPSPNRDP

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI154350220, Length=309, Percent_Identity=30.0970873786408, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI84043967, Length=346, Percent_Identity=30.3468208092486, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI7706681, Length=347, Percent_Identity=30.2593659942363, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=46.2962962962963, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI5729982, Length=134, Percent_Identity=39.5522388059701, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1786425, Length=362, Percent_Identity=36.4640883977901, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1787432, Length=309, Percent_Identity=28.4789644012945, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17537959, Length=303, Percent_Identity=28.3828382838284, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193205702, Length=228, Percent_Identity=29.8245614035088, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI193205700, Length=228, Percent_Identity=29.8245614035088, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115534089, Length=140, Percent_Identity=36.4285714285714, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI19923006, Length=343, Percent_Identity=26.2390670553936, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI21355641, Length=385, Percent_Identity=25.4545454545455, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24644984, Length=385, Percent_Identity=25.4545454545455, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24668444, Length=119, Percent_Identity=39.4957983193277, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 46306; Mature: 46306

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS50173 UMUC ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTYFHVDMDAFFVSVEELFDPSLKGKPVVVGGQSNERGVVSAASYAARKFGVHSAMPLR
CCEEEEECHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHH
TAYKLCPQAIFVDGHPDRYREYSHRVHEVLESFSPLVEMASVDEAYLDITGTERLYGPPL
HHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCH
RAAHLLHERMKAATKLNCSIGIAASRLVAKITSDQAKPNGIMWILAGREAAFLAPLDVRK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCCHHH
IPGVGKVTEKNLHLLGIRKVGDLARLDDAFLEERFGKWGMALAGKSRGLDAGGWFDTEIG
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCC
EEQGPKSISHEHTFNEDTADLGQIESTLARLSEMVGRRLREQALEARTLQLKLRYSDFST
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEECHHHH
ITRAHSLPRATQLDTEIYEEIRELFRRNWKRGATVRLLGVHASGWADGDEQMHLLGEDRH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHCCCHHH
QKWKETLAAADRMRDRFGEKAVSLAASLRGNFKERTHENPVGLPGKKPSPNRDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRTYFHVDMDAFFVSVEELFDPSLKGKPVVVGGQSNERGVVSAASYAARKFGVHSAMPLR
CCEEEEECHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHH
TAYKLCPQAIFVDGHPDRYREYSHRVHEVLESFSPLVEMASVDEAYLDITGTERLYGPPL
HHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCCCCCH
RAAHLLHERMKAATKLNCSIGIAASRLVAKITSDQAKPNGIMWILAGREAAFLAPLDVRK
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCCHHH
IPGVGKVTEKNLHLLGIRKVGDLARLDDAFLEERFGKWGMALAGKSRGLDAGGWFDTEIG
CCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCC
EEQGPKSISHEHTFNEDTADLGQIESTLARLSEMVGRRLREQALEARTLQLKLRYSDFST
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEECHHHH
ITRAHSLPRATQLDTEIYEEIRELFRRNWKRGATVRLLGVHASGWADGDEQMHLLGEDRH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHCCCHHH
QKWKETLAAADRMRDRFGEKAVSLAASLRGNFKERTHENPVGLPGKKPSPNRDP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA