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The map label for this gene is atpB

Identifier: 116619894

GI number: 116619894

Start: 964329

End: 965030

Strand: Direct

Name: atpB

Synonym: Acid_0766

Alternate gene names: 116619894

Gene position: 964329-965030 (Clockwise)

Preceding gene: 116619893

Following gene: 116619895

Centisome position: 9.68

GC content: 58.12

Gene sequence:

>702_bases
TTGTTCAACGATCACCTGGCCGGCGCCGGCAACGCGCTGACCGGCATCGTCGGCATGGCGCCGGAAGCCCGTCCGTGGGC
CAACTTCGTCACCATGCAACTGCTGGTCGTGGCAATCATCGTGGTGCTGTTCGCAATCCTCCGGCCCAGGTTATCGCCGG
ACCGTCCGGGAAAACTGCAGCACACATTCGAACTGGTCTATGGCTTCCTGCACGAGCAGGCCGAAGAGCAGATTGGTCAT
GAGGGACATCATTACCTCGCCTTCTTCGGTACCATTTTCATCTTCATTCTGTTTGCCAACCTGATCGGCGTAGTCCCCGG
TTTCGAGGCGCCTACCATGGTGCCTTCAGTCCCCGCCGGCTGCGCGATCGCCGCGTTCTTCTACTACAATATCGTGGGCG
TTCAGGCCAACGGTCTCGGCCGCTACCTGGCGCATTTCGCTGGGCCCATGCCCTTGCTCGCGCCCCTGATGATTCCCATC
GAACTGGTCAGCCACATGGCGCGGCCCCTCTCGCTCACCATCCGCCTCTTCGCCAACATGTATGCCGGCGAACAGGTGAC
CATGGTATTTCTTAAACTTACTTTTCTCTTTGTGCCTGCGGTTTTCATGGGGCTGCACGTCTTTGTTTCTTTCCTGCAGG
CCTATATCTTTATGCTCCTGACCATGATGTATGTGGCCGGGGCAGTTGCGCACGAACACTAA

Upstream 100 bases:

>100_bases
CCTGCCGCATTGGCGGGCTTGTTCGTATCGGTTGCGGCAGTGGTAATCGAAATCCTTTTCGAACTGGTATATGCACGAAA
CGGAACTGTGGATCACTAGG

Downstream 100 bases:

>100_bases
TAACGGCTTTATGCCGCCCTTTCAGTGTGAGCCCGGCTGCTAGAGGATGACGGGGACCACCTCCTGGGGGCGATTTCTTA
GGAGAGTACGATGAATAAAA

Product: ATP synthase F0 subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MFNDHLAGAGNALTGIVGMAPEARPWANFVTMQLLVVAIIVVLFAILRPRLSPDRPGKLQHTFELVYGFLHEQAEEQIGH
EGHHYLAFFGTIFIFILFANLIGVVPGFEAPTMVPSVPAGCAIAAFFYYNIVGVQANGLGRYLAHFAGPMPLLAPLMIPI
ELVSHMARPLSLTIRLFANMYAGEQVTMVFLKLTFLFVPAVFMGLHVFVSFLQAYIFMLLTMMYVAGAVAHEH

Sequences:

>Translated_233_residues
MFNDHLAGAGNALTGIVGMAPEARPWANFVTMQLLVVAIIVVLFAILRPRLSPDRPGKLQHTFELVYGFLHEQAEEQIGH
EGHHYLAFFGTIFIFILFANLIGVVPGFEAPTMVPSVPAGCAIAAFFYYNIVGVQANGLGRYLAHFAGPMPLLAPLMIPI
ELVSHMARPLSLTIRLFANMYAGEQVTMVFLKLTFLFVPAVFMGLHVFVSFLQAYIFMLLTMMYVAGAVAHEH
>Mature_233_residues
MFNDHLAGAGNALTGIVGMAPEARPWANFVTMQLLVVAIIVVLFAILRPRLSPDRPGKLQHTFELVYGFLHEQAEEQIGH
EGHHYLAFFGTIFIFILFANLIGVVPGFEAPTMVPSVPAGCAIAAFFYYNIVGVQANGLGRYLAHFAGPMPLLAPLMIPI
ELVSHMARPLSLTIRLFANMYAGEQVTMVFLKLTFLFVPAVFMGLHVFVSFLQAYIFMLLTMMYVAGAVAHEH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=204, Percent_Identity=29.9019607843137, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_SOLUE (Q02B01)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_822050.1
- ProteinModelPortal:   Q02B01
- SMR:   Q02B01
- STRING:   Q02B01
- GeneID:   4431095
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_0766
- NMPDR:   fig|234267.9.peg.720
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   DAQKHLS
- PhylomeDB:   Q02B01
- ProtClustDB:   CLSK774506
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 25668; Mature: 25668

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x140404b8)-; HASH(0x13397fa0)-; HASH(0x140a997c)-; HASH(0x1433a91c)-; HASH(0x1515ad2c)-; HASH(0x147200ec)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNDHLAGAGNALTGIVGMAPEARPWANFVTMQLLVVAIIVVLFAILRPRLSPDRPGKLQ
CCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
HTFELVYGFLHEQAEEQIGHEGHHYLAFFGTIFIFILFANLIGVVPGFEAPTMVPSVPAG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
CAIAAFFYYNIVGVQANGLGRYLAHFAGPMPLLAPLMIPIELVSHMARPLSLTIRLFANM
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAGEQVTMVFLKLTFLFVPAVFMGLHVFVSFLQAYIFMLLTMMYVAGAVAHEH
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MFNDHLAGAGNALTGIVGMAPEARPWANFVTMQLLVVAIIVVLFAILRPRLSPDRPGKLQ
CCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
HTFELVYGFLHEQAEEQIGHEGHHYLAFFGTIFIFILFANLIGVVPGFEAPTMVPSVPAG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
CAIAAFFYYNIVGVQANGLGRYLAHFAGPMPLLAPLMIPIELVSHMARPLSLTIRLFANM
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAGEQVTMVFLKLTFLFVPAVFMGLHVFVSFLQAYIFMLLTMMYVAGAVAHEH
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA