Click here to switch to the map view.

The map label for this gene is yjjA [H]

Identifier: 116619889

GI number: 116619889

Start: 959829

End: 960581

Strand: Direct

Name: yjjA [H]

Synonym: Acid_0761

Alternate gene names: 116619889

Gene position: 959829-960581 (Clockwise)

Preceding gene: 116619887

Following gene: 116619892

Centisome position: 9.63

GC content: 63.75

Gene sequence:

>753_bases
ATGGAGCAGTTGATTCGCAAGCAGGGGGGTGAACCTTTCGTGGCACCTTCCATGCGCGAAATCCCGCTGACGGATAACGA
GGAGGCTTTCGCCTTCGCCGAACGGCTTTTCGCCGGCGAGTTCGATATGGCAATTTTCCTGACCGGCGTGGGCACGCGCC
TGATGGATCGCGTACTGGCGACCCGGTACGACCAGGGCGCGCTGGCGGCGGCGCTGCGGCGCATCGCGGTGGTGGCCCGC
GGTCCCAAGCCTGCCGCCGCCCTTCGTGAAATGGGAGTCGCCCCCGCCGTAATCGCGCCCGAGCCGAACACTTGGCGGGA
ACTGCTGGCCGCGATCGAAGGCCGCATGGAGCGGCGCATCGCCGTCCAGGAATATGGGCGCCCCAGCCAGGAATTGCTCG
ATGGGCTGCGTGCGCGCGGCGCCGAAGTTACCCGCGTGCGCATCTACCAATGGGAATTGCCCGAGGACACTCAGCCGCTT
CGTGAAGCGGTACGGCGTTTGAGCGCAGGAGCCATTGATATCGTGCTGTTTACGACAGCCATCCAGATGGCTCACCTGGC
GCGCATCGCGCGTGAAGAAGGCCTGGAGGCGGCGCTCCTCGAAAACTTGCGCAAGTGCCGGGTATGTTCGATTGGACCCA
CCACTACCGAGGCGCTCGAAGAGTTCGGAGTGCATCCTGCGATGGAGCCATCCCATCCGAAAATGGGGTTCCTGGTTAAG
GAAGCCGCGGAAGGCGCGAATGGGCATGAATAA

Upstream 100 bases:

>100_bases
ATAGCTCTCTAAAGTTATAGCCCATACCGATGGTTATAATCCTGGCATGGGATTCGGCGGAGCGCGAGTGCTGTCGTTGG
AGAGCCGCAGGGCGGCGGAA

Downstream 100 bases:

>100_bases
AGAACCCACCCACGAACATGTTGTTTCGGTGAGCGCGGTTTTTTACTCTGTGCGAAGCGCGACCATCGGGTCCACACGGG
CCGCCCGCCGGGCCGGGATC

Product: uroporphyrinogen III synthase HEM4

Products: coproporphyrinogen; CO2

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MEQLIRKQGGEPFVAPSMREIPLTDNEEAFAFAERLFAGEFDMAIFLTGVGTRLMDRVLATRYDQGALAAALRRIAVVAR
GPKPAAALREMGVAPAVIAPEPNTWRELLAAIEGRMERRIAVQEYGRPSQELLDGLRARGAEVTRVRIYQWELPEDTQPL
REAVRRLSAGAIDIVLFTTAIQMAHLARIAREEGLEAALLENLRKCRVCSIGPTTTEALEEFGVHPAMEPSHPKMGFLVK
EAAEGANGHE

Sequences:

>Translated_250_residues
MEQLIRKQGGEPFVAPSMREIPLTDNEEAFAFAERLFAGEFDMAIFLTGVGTRLMDRVLATRYDQGALAAALRRIAVVAR
GPKPAAALREMGVAPAVIAPEPNTWRELLAAIEGRMERRIAVQEYGRPSQELLDGLRARGAEVTRVRIYQWELPEDTQPL
REAVRRLSAGAIDIVLFTTAIQMAHLARIAREEGLEAALLENLRKCRVCSIGPTTTEALEEFGVHPAMEPSHPKMGFLVK
EAAEGANGHE
>Mature_250_residues
MEQLIRKQGGEPFVAPSMREIPLTDNEEAFAFAERLFAGEFDMAIFLTGVGTRLMDRVLATRYDQGALAAALRRIAVVAR
GPKPAAALREMGVAPAVIAPEPNTWRELLAAIEGRMERRIAVQEYGRPSQELLDGLRARGAEVTRVRIYQWELPEDTQPL
REAVRRLSAGAIDIVLFTTAIQMAHLARIAREEGLEAALLENLRKCRVCSIGPTTTEALEEFGVHPAMEPSHPKMGFLVK
EAAEGANGHE

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003754 [H]

Pfam domain/function: PF02602 HEM4 [H]

EC number: 4.1.1.37; 4.2.1.75

Molecular weight: Translated: 27551; Mature: 27551

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLIRKQGGEPFVAPSMREIPLTDNEEAFAFAERLFAGEFDMAIFLTGVGTRLMDRVLA
CCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
TRYDQGALAAALRRIAVVARGPKPAAALREMGVAPAVIAPEPNTWRELLAAIEGRMERRI
HCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
AVQEYGRPSQELLDGLRARGAEVTRVRIYQWELPEDTQPLREAVRRLSAGAIDIVLFTTA
HHHHCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHH
IQMAHLARIAREEGLEAALLENLRKCRVCSIGPTTTEALEEFGVHPAMEPSHPKMGFLVK
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHH
EAAEGANGHE
HHHCCCCCCC
>Mature Secondary Structure
MEQLIRKQGGEPFVAPSMREIPLTDNEEAFAFAERLFAGEFDMAIFLTGVGTRLMDRVLA
CCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
TRYDQGALAAALRRIAVVARGPKPAAALREMGVAPAVIAPEPNTWRELLAAIEGRMERRI
HCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHH
AVQEYGRPSQELLDGLRARGAEVTRVRIYQWELPEDTQPLREAVRRLSAGAIDIVLFTTA
HHHHCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHH
IQMAHLARIAREEGLEAALLENLRKCRVCSIGPTTTEALEEFGVHPAMEPSHPKMGFLVK
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHH
EAAEGANGHE
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: uroporphyrinogen III

Specific reaction: uroporphyrinogen III = coproporphyrinogen + 4 CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]