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The map label for this gene is argB

Identifier: 116619852

GI number: 116619852

Start: 911257

End: 912030

Strand: Direct

Name: argB

Synonym: Acid_0724

Alternate gene names: 116619852

Gene position: 911257-912030 (Clockwise)

Preceding gene: 116619851

Following gene: 116619853

Centisome position: 9.14

GC content: 64.86

Gene sequence:

>774_bases
GTGAAGCTGCTGGTGAAACTGGGCGGCACTCTGCTCGATTCCGCGGCTTCGCGCGACAGCCTGTGCCTGCAGATCGCGGC
CGCCCGCGCCGCCGGCCACGAGGTCACGGTAGTTCACGGAGGCGGCAAGCAGATGACCCGCTACCTCACCGATCGCGGCA
TCGAAAGCCGGTTCGTCGGCGGGCTGCGCGTCACCTCGCCCGACACAATCGACGCTGTGCTCAAAGTCTTCGCTGGAAGT
GTGAACCACGAACTGGTCGCCAACCTGAACCGTGCCGGAGCCTTGGCCGTGGGGCTTTCCGGAATCGATAGCTTCCTGGT
GGAGGCGGAGCAGATGGATCCCGAACTCGGCGCCGTCGGCCGCGTCACCGGCTCCAACCCCGCTTTGCTCCATTTGCTGA
CCGCGAACGGCTATGTGCCCGTAGTCGCCTGTGTGGCCGGCGACCGGCTGGGCCAGATCTATAACGTGAATGCCGACCAG
ATGGCCGTGGCCTGCGCCTCCGCGTTCGGCGCCTGCCGGCTCATTTTCCTGACGGACGTCGATGGTGTCATGGACAACTC
GAACAGGGTCCGTCCCGTACTGACGGCGGCAGAGAGCCGGCAATTGATTGACGAAGGCATAGCTACCGGGGGTATGCAGG
CCAAACTCAACGCCGCCCTCAGCGCCCTGGCGGACGGTGTTCAGCAGGTGCGGATCGCCCCGGGAGCAGCGCCCGGGGCA
CTCCAAAGAATCCTCGCCGGTGAAGAAATCGGCACGAAAATGGTGACAGCATGA

Upstream 100 bases:

>100_bases
TGGTGGTCGCCGCCATCGACAATCTGGTGAAAGGCGCCGCCGGACAGGCCGTGCAGAACATGAACCTGATGCTCGGCTAT
GCCGAGACCGAGGCGCTGCT

Downstream 100 bases:

>100_bases
TCAGCAGCGTGCGTGCAGATGCGTTTGTTCCTTCCGGCGGAAAATCCGCGCGGGTCGTGGTTCGCAAGGCTACGATGCGC
GATATCGCGCCCATCTTGAA

Product: N-acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKLLVKLGGTLLDSAASRDSLCLQIAAARAAGHEVTVVHGGGKQMTRYLTDRGIESRFVGGLRVTSPDTIDAVLKVFAGS
VNHELVANLNRAGALAVGLSGIDSFLVEAEQMDPELGAVGRVTGSNPALLHLLTANGYVPVVACVAGDRLGQIYNVNADQ
MAVACASAFGACRLIFLTDVDGVMDNSNRVRPVLTAAESRQLIDEGIATGGMQAKLNAALSALADGVQQVRIAPGAAPGA
LQRILAGEEIGTKMVTA

Sequences:

>Translated_257_residues
MKLLVKLGGTLLDSAASRDSLCLQIAAARAAGHEVTVVHGGGKQMTRYLTDRGIESRFVGGLRVTSPDTIDAVLKVFAGS
VNHELVANLNRAGALAVGLSGIDSFLVEAEQMDPELGAVGRVTGSNPALLHLLTANGYVPVVACVAGDRLGQIYNVNADQ
MAVACASAFGACRLIFLTDVDGVMDNSNRVRPVLTAAESRQLIDEGIATGGMQAKLNAALSALADGVQQVRIAPGAAPGA
LQRILAGEEIGTKMVTA
>Mature_257_residues
MKLLVKLGGTLLDSAASRDSLCLQIAAARAAGHEVTVVHGGGKQMTRYLTDRGIESRFVGGLRVTSPDTIDAVLKVFAGS
VNHELVANLNRAGALAVGLSGIDSFLVEAEQMDPELGAVGRVTGSNPALLHLLTANGYVPVVACVAGDRLGQIYNVNADQ
MAVACASAFGACRLIFLTDVDGVMDNSNRVRPVLTAAESRQLIDEGIATGGMQAKLNAALSALADGVQQVRIAPGAAPGA
LQRILAGEEIGTKMVTA

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=254, Percent_Identity=36.6141732283465, Blast_Score=128, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320913, Length=185, Percent_Identity=27.5675675675676, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_SOLUE (Q02B43)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_822008.1
- ProteinModelPortal:   Q02B43
- SMR:   Q02B43
- STRING:   Q02B43
- GeneID:   4431140
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_0724
- NMPDR:   fig|234267.9.peg.677
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   Q02B43
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 26429; Mature: 26429

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: BINDING 63-63 BINDING 155-155

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLVKLGGTLLDSAASRDSLCLQIAAARAAGHEVTVVHGGGKQMTRYLTDRGIESRFVG
CEEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCHHHHCC
GLRVTSPDTIDAVLKVFAGSVNHELVANLNRAGALAVGLSGIDSFLVEAEQMDPELGAVG
CEEECCCHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEE
RVTGSNPALLHLLTANGYVPVVACVAGDRLGQIYNVNADQMAVACASAFGACRLIFLTDV
EECCCCCEEEEEEECCCCEEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCEEEEEEECC
DGVMDNSNRVRPVLTAAESRQLIDEGIATGGMQAKLNAALSALADGVQQVRIAPGAAPGA
CCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCCHHH
LQRILAGEEIGTKMVTA
HHHHHCCHHHCCCCCCC
>Mature Secondary Structure
MKLLVKLGGTLLDSAASRDSLCLQIAAARAAGHEVTVVHGGGKQMTRYLTDRGIESRFVG
CEEEEECCCHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCHHHHCC
GLRVTSPDTIDAVLKVFAGSVNHELVANLNRAGALAVGLSGIDSFLVEAEQMDPELGAVG
CEEECCCHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEE
RVTGSNPALLHLLTANGYVPVVACVAGDRLGQIYNVNADQMAVACASAFGACRLIFLTDV
EECCCCCEEEEEEECCCCEEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCEEEEEEECC
DGVMDNSNRVRPVLTAAESRQLIDEGIATGGMQAKLNAALSALADGVQQVRIAPGAAPGA
CCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEECCCCCHHH
LQRILAGEEIGTKMVTA
HHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA