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The map label for this gene is rsbX [H]

Identifier: 116619667

GI number: 116619667

Start: 640069

End: 641103

Strand: Direct

Name: rsbX [H]

Synonym: Acid_0530

Alternate gene names: 116619667

Gene position: 640069-641103 (Clockwise)

Preceding gene: 116619666

Following gene: 116619668

Centisome position: 6.42

GC content: 66.28

Gene sequence:

>1035_bases
TTGAGCACGAATGTCGCCATTACGGTGCGGGAAAGCTCAGATGTCGGCGCTGCGCGCCGCGCTGCCGCCGCGCTTTCCCG
CGCCCTGGACCTGGACTCCACCATCGCCGGACAGGCCGCCATCGTGGTCACCGAAGCCGCCACCAACCTGGTCAAGCACG
GCGGCGGTGGTGTAATTCTGCTCAACCGAATCGGCGCCCCCGACAGCCCCGTGATGGAAATCCTGGCCCTCGACAAGGGC
CCCGGCATGCACAGCGTCGAACGCTCCATGGAAGATGGCTACTCCACCGCCGGCAGTCCCGGCAACGGACTGGGTGCGAT
TGCGCGCCTCTCCAGCTTTCACGACATCTATTCGTCTCCCGGACTCGGCACCGTCGTGCTCGCTCACCTGGGAAGTCCGC
CCGCCGGTCCGCGGCGCCCCGCGCCCTCCCGCTTTCAGGTCGGCGCGGTCAGTGTGCCCAAGGGCGTCGAGCCTGTCTGC
GGAGATGCCTGGGTTACCGAAGCCCGGGAGCACGGCCTGCGCGTGATCGTGGTCGATGGCTTGGGCCATGGCATGGGTGC
CTTCGAAGCCTCCAAAGCCGCGCTCGAAATCGCCGCCGCCCATTCGCGGGATATGGCGCTCCCGTTGATGGAACGCATTC
ACGCCGGCCTGCGCGCCACCCGCGGCGCCGCTGTTTCGGTCGCCGAGATCGATCTCGAACTGGGAAGCGTGACCTACGCC
GGCCTTGGAAATGTCGCCGGTTCGCTGATCTCCCCCGGCGGCCTCCGCCGCCAGATGATCTCGTACAACGGTACCGCGGG
CCACAACGCCCATAAAATTCGCGAGCTGAACTACCCCTGGGCTCCGGACACGATTCTCGTGATTCACTCCGACGGGCTCG
CCACTCATTGGACTCTCGACAAATACCCCGGCCTGCATCGCCGCCACCCCAGCATTATCGCCGGCATCTTATTCCGCGAT
TTCCAGCGCGGCACCGATGACGCCACGGTGGTGGTCGTGCGCTTCGCCGGCGGCACTCAAGAGGACAGGCTATGA

Upstream 100 bases:

>100_bases
AGCGGCTCTCCAATGAATTTGAGATCGACTCACGCCCCGGCGAAGGTACACGGGTCACCATCGTCCGCTGGAAATAGTTC
TGTCTTGGGGAGCCCTGAAG

Downstream 100 bases:

>100_bases
CTTTCGACCAGCCATCTCGCACCGACCAGTCCGACGAAGCCGCCACTATCCCGATTCTCACGGTCAGCATCCTCGAGGAA
TCCGACGTCGTTGCCGCCCG

Product: putative anti-sigma regulatory factor, serine/threonine protein kinase

Products: NA

Alternate protein names: Sigma-B negative effector [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MSTNVAITVRESSDVGAARRAAAALSRALDLDSTIAGQAAIVVTEAATNLVKHGGGGVILLNRIGAPDSPVMEILALDKG
PGMHSVERSMEDGYSTAGSPGNGLGAIARLSSFHDIYSSPGLGTVVLAHLGSPPAGPRRPAPSRFQVGAVSVPKGVEPVC
GDAWVTEAREHGLRVIVVDGLGHGMGAFEASKAALEIAAAHSRDMALPLMERIHAGLRATRGAAVSVAEIDLELGSVTYA
GLGNVAGSLISPGGLRRQMISYNGTAGHNAHKIRELNYPWAPDTILVIHSDGLATHWTLDKYPGLHRRHPSIIAGILFRD
FQRGTDDATVVVVRFAGGTQEDRL

Sequences:

>Translated_344_residues
MSTNVAITVRESSDVGAARRAAAALSRALDLDSTIAGQAAIVVTEAATNLVKHGGGGVILLNRIGAPDSPVMEILALDKG
PGMHSVERSMEDGYSTAGSPGNGLGAIARLSSFHDIYSSPGLGTVVLAHLGSPPAGPRRPAPSRFQVGAVSVPKGVEPVC
GDAWVTEAREHGLRVIVVDGLGHGMGAFEASKAALEIAAAHSRDMALPLMERIHAGLRATRGAAVSVAEIDLELGSVTYA
GLGNVAGSLISPGGLRRQMISYNGTAGHNAHKIRELNYPWAPDTILVIHSDGLATHWTLDKYPGLHRRHPSIIAGILFRD
FQRGTDDATVVVVRFAGGTQEDRL
>Mature_343_residues
STNVAITVRESSDVGAARRAAAALSRALDLDSTIAGQAAIVVTEAATNLVKHGGGGVILLNRIGAPDSPVMEILALDKGP
GMHSVERSMEDGYSTAGSPGNGLGAIARLSSFHDIYSSPGLGTVVLAHLGSPPAGPRRPAPSRFQVGAVSVPKGVEPVCG
DAWVTEAREHGLRVIVVDGLGHGMGAFEASKAALEIAAAHSRDMALPLMERIHAGLRATRGAAVSVAEIDLELGSVTYAG
LGNVAGSLISPGGLRRQMISYNGTAGHNAHKIRELNYPWAPDTILVIHSDGLATHWTLDKYPGLHRRHPSIIAGILFRDF
QRGTDDATVVVVRFAGGTQEDRL

Specific function: Negative regulator of sigma-B activity. Dephosphorylates rsbS. Plays a role both in maintaining low sigma-B activity during growth and in reestablishing prestress sigma-B activity after induction. Could have a negative feedback role by indirectly communic

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001932
- InterPro:   IPR010822 [H]

Pfam domain/function: PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35790; Mature: 35659

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNVAITVRESSDVGAARRAAAALSRALDLDSTIAGQAAIVVTEAATNLVKHGGGGVIL
CCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHCCCCCEEE
LNRIGAPDSPVMEILALDKGPGMHSVERSMEDGYSTAGSPGNGLGAIARLSSFHDIYSSP
EECCCCCCCHHEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCC
GLGTVVLAHLGSPPAGPRRPAPSRFQVGAVSVPKGVEPVCGDAWVTEAREHGLRVIVVDG
CHHHHHEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEECC
LGHGMGAFEASKAALEIAAAHSRDMALPLMERIHAGLRATRGAAVSVAEIDLELGSVTYA
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCEEEC
GLGNVAGSLISPGGLRRQMISYNGTAGHNAHKIRELNYPWAPDTILVIHSDGLATHWTLD
CHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHEECCCCCCCCEEEEEECCCCEEEEEHH
KYPGLHRRHPSIIAGILFRDFQRGTDDATVVVVRFAGGTQEDRL
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
STNVAITVRESSDVGAARRAAAALSRALDLDSTIAGQAAIVVTEAATNLVKHGGGGVIL
CCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHCCCCCEEE
LNRIGAPDSPVMEILALDKGPGMHSVERSMEDGYSTAGSPGNGLGAIARLSSFHDIYSSP
EECCCCCCCHHEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCC
GLGTVVLAHLGSPPAGPRRPAPSRFQVGAVSVPKGVEPVCGDAWVTEAREHGLRVIVVDG
CHHHHHEEECCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEECC
LGHGMGAFEASKAALEIAAAHSRDMALPLMERIHAGLRATRGAAVSVAEIDLELGSVTYA
CCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCEEEC
GLGNVAGSLISPGGLRRQMISYNGTAGHNAHKIRELNYPWAPDTILVIHSDGLATHWTLD
CHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHEECCCCCCCCEEEEEECCCCEEEEEHH
KYPGLHRRHPSIIAGILFRDFQRGTDDATVVVVRFAGGTQEDRL
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2170324; 9384377; 3027048; 1592822; 8468294; 8824586; 9658013 [H]