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The map label for this gene is fliI [H]

Identifier: 116619484

GI number: 116619484

Start: 438623

End: 439972

Strand: Direct

Name: fliI [H]

Synonym: Acid_0343

Alternate gene names: 116619484

Gene position: 438623-439972 (Clockwise)

Preceding gene: 116619483

Following gene: 116619485

Centisome position: 4.4

GC content: 65.11

Gene sequence:

>1350_bases
ATGAATATCGACCTCGCCCCCTACATCTCCCATCTCGATCGCGTCAATCCGCTGCGCTGGACCGGACAGGTCACCCAAGT
CGTCGGACTCCTCATAGAGTCGCGCGGACCCAGCGTCGCGATCGGCGATTTCTGTGAAGTCAAAACCGCCTCCGGCCGCC
GTATTCACACTCAGGTCATTGGCTTCCGCGACGGCCGCGTCCTGTCCATGCCGCTCGAGGAAATCGACGGCCTTCAGCTC
GGCGATCCCTTGGCGGCGCGCAGTGAAGACGCGCGCGTCGAAGTTGGCCCGGGCCTCCTCGGCCGCGTCATCGATGGCTT
CGGCAAGCCTATGGATACCGGCCCGGCCATCAATGCCCGCGAATCCTACAGCCTGCACGGCACGCCCACTAACCCGCTCG
ATCGCCAGCACATCACCCAGCCCCTCGTTACCGGCATCCGCGCCATCGACGCCCTGCTCCCCTGCGGCAAAGGCCAGCGC
ATCGGCATCTTTGGAGGCAGCGGCGTCGGTAAAAGTACCCTCCTCGGCTCCATGTCGCGCAACAATTCGGCCGACGTCAC
CGTCATCGCCATGATCGGCGAGCGCAATCGCGAAGTCCGCGGCTTCCTCGAAAACGAGCTCGGTCCCGAGGGCCGCAAGC
GCTCCGTCGTCGTCTGCGCCACCAGCGAGCGCCCCGCGCCCCTCCGCGTCCGCGCTTGCTTCGTCTCCCTCGCTATCGCC
GAGTACTTCCGCGACCAGGGCGCCAACGTCCTCCTCGTCATGGATTCCGTCACCCGCCTGGCCATGGCGCAGCGCGAAAT
CGGCCTCGCCGCCGGCGAACCCCCCAGCCAGAAGGGCTACACCCCGTCGGTATTCAATCTCCTCCCCAAGGTGCTCGAAC
GCGCCGGAAACTTCGGCCGCGGCTCCATCACCGGCTTCTTCACTGTCCTCGTCGAAGGCGACGATTTCAACGAGCCCATC
TGCGATGCCGTCCGCGGCATCCTCGATGGCCACTTCATCCTCTCGCGCGACCTCGGCGCCCAGGGACACTATCCCGCGAT
CGATATTCTCCACTCCGTCAGCCGTCTCACCAGCGCCATCGCAACGCCCGCGCAGAAGGAGGCCGCTCGCAAAATCCGCG
CTGCCCTCGCCGCTTATCGCGATGCGGAGGACCTGATCCAGCTCGGCGCCTATGTTTCCGGCTCTAATCCCGATCTCGAC
GCCAGCATCCACCTCCGCCCCGAACTCCTCGACTTCCTTCGCCAGGACCACCTAGTAGTCTCCACTCTCGAGGAAACTCT
TCGCCGCCTTGAAGCCCTGGCCACCCAGCTCCAGCACCTGCCTGCAACCCAAGCCGGTAACAAACGATGA

Upstream 100 bases:

>100_bases
ACGTCGTGTTTGAAACCCAGCGCGGCAATCTCGATGCCTCCGTCGAATCGCAGCTCCAGGAAATCGAGCGCGGGCTCGCC
GACCGCCTCCGCAAACAGCC

Downstream 100 bases:

>100_bases
AGACCTTCCATTTCCCTCTTGAAAAGGCCCTCGAATGGCGCCGCATCGAGCTCGAGCTCGAAGAGGCCCGCTATAAACAG
CAGTCCGCCGAACTCACCGC

Product: FliI/YscN family ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MNIDLAPYISHLDRVNPLRWTGQVTQVVGLLIESRGPSVAIGDFCEVKTASGRRIHTQVIGFRDGRVLSMPLEEIDGLQL
GDPLAARSEDARVEVGPGLLGRVIDGFGKPMDTGPAINARESYSLHGTPTNPLDRQHITQPLVTGIRAIDALLPCGKGQR
IGIFGGSGVGKSTLLGSMSRNNSADVTVIAMIGERNREVRGFLENELGPEGRKRSVVVCATSERPAPLRVRACFVSLAIA
EYFRDQGANVLLVMDSVTRLAMAQREIGLAAGEPPSQKGYTPSVFNLLPKVLERAGNFGRGSITGFFTVLVEGDDFNEPI
CDAVRGILDGHFILSRDLGAQGHYPAIDILHSVSRLTSAIATPAQKEAARKIRAALAAYRDAEDLIQLGAYVSGSNPDLD
ASIHLRPELLDFLRQDHLVVSTLEETLRRLEALATQLQHLPATQAGNKR

Sequences:

>Translated_449_residues
MNIDLAPYISHLDRVNPLRWTGQVTQVVGLLIESRGPSVAIGDFCEVKTASGRRIHTQVIGFRDGRVLSMPLEEIDGLQL
GDPLAARSEDARVEVGPGLLGRVIDGFGKPMDTGPAINARESYSLHGTPTNPLDRQHITQPLVTGIRAIDALLPCGKGQR
IGIFGGSGVGKSTLLGSMSRNNSADVTVIAMIGERNREVRGFLENELGPEGRKRSVVVCATSERPAPLRVRACFVSLAIA
EYFRDQGANVLLVMDSVTRLAMAQREIGLAAGEPPSQKGYTPSVFNLLPKVLERAGNFGRGSITGFFTVLVEGDDFNEPI
CDAVRGILDGHFILSRDLGAQGHYPAIDILHSVSRLTSAIATPAQKEAARKIRAALAAYRDAEDLIQLGAYVSGSNPDLD
ASIHLRPELLDFLRQDHLVVSTLEETLRRLEALATQLQHLPATQAGNKR
>Mature_449_residues
MNIDLAPYISHLDRVNPLRWTGQVTQVVGLLIESRGPSVAIGDFCEVKTASGRRIHTQVIGFRDGRVLSMPLEEIDGLQL
GDPLAARSEDARVEVGPGLLGRVIDGFGKPMDTGPAINARESYSLHGTPTNPLDRQHITQPLVTGIRAIDALLPCGKGQR
IGIFGGSGVGKSTLLGSMSRNNSADVTVIAMIGERNREVRGFLENELGPEGRKRSVVVCATSERPAPLRVRACFVSLAIA
EYFRDQGANVLLVMDSVTRLAMAQREIGLAAGEPPSQKGYTPSVFNLLPKVLERAGNFGRGSITGFFTVLVEGDDFNEPI
CDAVRGILDGHFILSRDLGAQGHYPAIDILHSVSRLTSAIATPAQKEAARKIRAALAAYRDAEDLIQLGAYVSGSNPDLD
ASIHLRPELLDFLRQDHLVVSTLEETLRRLEALATQLQHLPATQAGNKR

Specific function: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum [H]

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=445, Percent_Identity=27.4157303370787, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI50345984, Length=326, Percent_Identity=31.5950920245399, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI4757810, Length=326, Percent_Identity=31.5950920245399, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI19913424, Length=302, Percent_Identity=30.4635761589404, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI19913428, Length=321, Percent_Identity=30.2180685358255, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI19913426, Length=286, Percent_Identity=29.020979020979, Blast_Score=111, Evalue=1e-24,
Organism=Escherichia coli, GI1788251, Length=436, Percent_Identity=45.6422018348624, Blast_Score=354, Evalue=6e-99,
Organism=Escherichia coli, GI1790170, Length=439, Percent_Identity=28.4738041002278, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1790172, Length=315, Percent_Identity=29.8412698412698, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI25144756, Length=401, Percent_Identity=30.4239401496259, Blast_Score=165, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI71988063, Length=354, Percent_Identity=32.4858757062147, Blast_Score=164, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI71988080, Length=354, Percent_Identity=32.4858757062147, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71988074, Length=351, Percent_Identity=31.0541310541311, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17565854, Length=314, Percent_Identity=30.2547770700637, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17570191, Length=424, Percent_Identity=27.3584905660377, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17510931, Length=318, Percent_Identity=28.6163522012579, Blast_Score=117, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6319370, Length=354, Percent_Identity=34.7457627118644, Blast_Score=175, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6322581, Length=381, Percent_Identity=30.1837270341207, Blast_Score=162, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6319603, Length=321, Percent_Identity=29.595015576324, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320016, Length=258, Percent_Identity=29.0697674418605, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24658560, Length=353, Percent_Identity=31.1614730878187, Blast_Score=158, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24638766, Length=470, Percent_Identity=28.2978723404255, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI28574560, Length=333, Percent_Identity=31.8318318318318, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24583988, Length=303, Percent_Identity=30.03300330033, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24583986, Length=303, Percent_Identity=30.03300330033, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24583984, Length=303, Percent_Identity=30.03300330033, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24583992, Length=302, Percent_Identity=30.1324503311258, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI20129479, Length=305, Percent_Identity=28.8524590163934, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI281361666, Length=384, Percent_Identity=26.5625, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24646341, Length=384, Percent_Identity=26.5625, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI17136796, Length=384, Percent_Identity=26.5625, Blast_Score=118, Evalue=7e-27,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000225
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR004100
- InterPro:   IPR005714
- InterPro:   IPR022425 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 48436; Mature: 48436

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDLAPYISHLDRVNPLRWTGQVTQVVGLLIESRGPSVAIGDFCEVKTASGRRIHTQVI
CCCCHHHHHHHHHCCCCCEECHHHHHHHHHHHHCCCCCEEECCCCEEECCCCCEEEEEEE
GFRDGRVLSMPLEEIDGLQLGDPLAARSEDARVEVGPGLLGRVIDGFGKPMDTGPAINAR
EECCCEEEECCHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCC
ESYSLHGTPTNPLDRQHITQPLVTGIRAIDALLPCGKGQRIGIFGGSGVGKSTLLGSMSR
CCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHCCCC
NNSADVTVIAMIGERNREVRGFLENELGPEGRKRSVVVCATSERPAPLRVRACFVSLAIA
CCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
EYFRDQGANVLLVMDSVTRLAMAQREIGLAAGEPPSQKGYTPSVFNLLPKVLERAGNFGR
HHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
GSITGFFTVLVEGDDFNEPICDAVRGILDGHFILSRDLGAQGHYPAIDILHSVSRLTSAI
CCEEEEEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
ATPAQKEAARKIRAALAAYRDAEDLIQLGAYVSGSNPDLDASIHLRPELLDFLRQDHLVV
CCCHHHHHHHHHHHHHHHHCCHHHHHHHCCEECCCCCCCCEEEEECHHHHHHHHHCCHHH
STLEETLRRLEALATQLQHLPATQAGNKR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNIDLAPYISHLDRVNPLRWTGQVTQVVGLLIESRGPSVAIGDFCEVKTASGRRIHTQVI
CCCCHHHHHHHHHCCCCCEECHHHHHHHHHHHHCCCCCEEECCCCEEECCCCCEEEEEEE
GFRDGRVLSMPLEEIDGLQLGDPLAARSEDARVEVGPGLLGRVIDGFGKPMDTGPAINAR
EECCCEEEECCHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCCCC
ESYSLHGTPTNPLDRQHITQPLVTGIRAIDALLPCGKGQRIGIFGGSGVGKSTLLGSMSR
CCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHCCCC
NNSADVTVIAMIGERNREVRGFLENELGPEGRKRSVVVCATSERPAPLRVRACFVSLAIA
CCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
EYFRDQGANVLLVMDSVTRLAMAQREIGLAAGEPPSQKGYTPSVFNLLPKVLERAGNFGR
HHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
GSITGFFTVLVEGDDFNEPICDAVRGILDGHFILSRDLGAQGHYPAIDILHSVSRLTSAI
CCEEEEEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
ATPAQKEAARKIRAALAAYRDAEDLIQLGAYVSGSNPDLDASIHLRPELLDFLRQDHLVV
CCCHHHHHHHHHHHHHHHHCCHHHHHHHCCEECCCCCCCCEEEEECHHHHHHHHHCCHHH
STLEETLRRLEALATQLQHLPATQAGNKR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1828465; 9384377 [H]