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The map label for this gene is 116619457

Identifier: 116619457

GI number: 116619457

Start: 412830

End: 413375

Strand: Direct

Name: 116619457

Synonym: Acid_0316

Alternate gene names: NA

Gene position: 412830-413375 (Clockwise)

Preceding gene: 116619449

Following gene: 116619461

Centisome position: 4.14

GC content: 66.85

Gene sequence:

>546_bases
GTGCGGCCGGCGGTAGAGGTCGCACGCGGCCTGCTTGGCAAGGTCCTGGTCCACGGCCCTACTGCGGGCGTGATCGTGGA
GACCGAGGCCTATCTGGGCGGCGACGACCTGGCAGCCCACTCCGCCCGGGGTATCACGGACCGCACTCGCGTGATTTTCG
GCCCTCCGGGCCACGCCTACGTCTATTTTATCTACGGTATGTACGAGTGCCTGAACCTGGTCGCCGAACCCCCCGGCCAT
CCCGGCTGCGTTCTCATTCGCGCCCTGGAGCCAATCGCCGGAATCGACCTCATGCAGCGCCGCCGCCCCGCTGCGCGTAA
GCCCGAGCAACTGGCCAACGGCCCCGGAAAACTGACGCTCGCGATGGCCATCACGCGTCGGCACAATGGAGTTGACGTAA
CCCGAGGCGCGCTCGTCGTGCGCGAAGCGGCCAACCCGGACCGGTTCGAGATCCTCACCACCCCACGGATTGGCATCACG
AAGTGCGTCGATCTCCCCCTCCGGTTCCTGATCGCCGGCAACCCATTTACCAGTCGCGGCCGCTAG

Upstream 100 bases:

>100_bases
ACCGGCAGGTCCAGTCCCGTGAACAATCTCATTTCGCGATTAACATTGTACTGTGCGGCGCAGTGTCCAACCCGGTCGAA
TTCTTCCGCGGACCTTCTAT

Downstream 100 bases:

>100_bases
GCGTTAGAGGAAATTCTGTGAATCGAACCGCTCCCTTCGGCCGGGCCCAATCGGCTGTAAGGGAGCGGTTGACCACAGTA
CTCGCTGCGACAATTCCGAG

Product: DNA-3-methyladenine glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MRPAVEVARGLLGKVLVHGPTAGVIVETEAYLGGDDLAAHSARGITDRTRVIFGPPGHAYVYFIYGMYECLNLVAEPPGH
PGCVLIRALEPIAGIDLMQRRRPAARKPEQLANGPGKLTLAMAITRRHNGVDVTRGALVVREAANPDRFEILTTPRIGIT
KCVDLPLRFLIAGNPFTSRGR

Sequences:

>Translated_181_residues
MRPAVEVARGLLGKVLVHGPTAGVIVETEAYLGGDDLAAHSARGITDRTRVIFGPPGHAYVYFIYGMYECLNLVAEPPGH
PGCVLIRALEPIAGIDLMQRRRPAARKPEQLANGPGKLTLAMAITRRHNGVDVTRGALVVREAANPDRFEILTTPRIGIT
KCVDLPLRFLIAGNPFTSRGR
>Mature_181_residues
MRPAVEVARGLLGKVLVHGPTAGVIVETEAYLGGDDLAAHSARGITDRTRVIFGPPGHAYVYFIYGMYECLNLVAEPPGH
PGCVLIRALEPIAGIDLMQRRRPAARKPEQLANGPGKLTLAMAITRRHNGVDVTRGALVVREAANPDRFEILTTPRIGIT
KCVDLPLRFLIAGNPFTSRGR

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family [H]

Homologues:

Organism=Homo sapiens, GI62632769, Length=196, Percent_Identity=38.265306122449, Blast_Score=111, Evalue=3e-25,
Organism=Homo sapiens, GI62632771, Length=196, Percent_Identity=38.265306122449, Blast_Score=111, Evalue=3e-25,
Organism=Homo sapiens, GI62632765, Length=196, Percent_Identity=38.265306122449, Blast_Score=111, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011034
- InterPro:   IPR003180 [H]

Pfam domain/function: PF02245 Pur_DNA_glyco [H]

EC number: 3.2.2.-

Molecular weight: Translated: 19552; Mature: 19552

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAVEVARGLLGKVLVHGPTAGVIVETEAYLGGDDLAAHSARGITDRTRVIFGPPGHAY
CCCHHHHHHHHHHHHEECCCCCCEEEEECCEECCCCHHHHCCCCCCCCCEEEECCCCCEE
VYFIYGMYECLNLVAEPPGHPGCVLIRALEPIAGIDLMQRRRPAARKPEQLANGPGKLTL
EEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCHHHHCCCCCEEE
AMAITRRHNGVDVTRGALVVREAANPDRFEILTTPRIGITKCVDLPLRFLIAGNPFTSRG
EEEEECCCCCCCEECCEEEEEECCCCCCEEEEECCCCCHHHHHHHCEEEEEECCCCCCCC
R
C
>Mature Secondary Structure
MRPAVEVARGLLGKVLVHGPTAGVIVETEAYLGGDDLAAHSARGITDRTRVIFGPPGHAY
CCCHHHHHHHHHHHHEECCCCCCEEEEECCEECCCCHHHHCCCCCCCCCEEEECCCCCEE
VYFIYGMYECLNLVAEPPGHPGCVLIRALEPIAGIDLMQRRRPAARKPEQLANGPGKLTL
EEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCHHHHCCCCCEEE
AMAITRRHNGVDVTRGALVVREAANPDRFEILTTPRIGITKCVDLPLRFLIAGNPFTSRG
EEEEECCCCCCCEECCEEEEEECCCCCCEEEEECCCCCHHHHHHHCEEEEEECCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA