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The map label for this gene is nuoA

Identifier: 116619253

GI number: 116619253

Start: 148148

End: 148555

Strand: Direct

Name: nuoA

Synonym: Acid_0109

Alternate gene names: 116619253

Gene position: 148148-148555 (Clockwise)

Preceding gene: 116619251

Following gene: 116619254

Centisome position: 1.49

GC content: 54.66

Gene sequence:

>408_bases
ATGCCTAAGTCCTACACCGAGTTGTATTTCCCTATCCTCTTGCAGGCCGTGATTGCAATGGGGCTGGCCGCCGGTCTGCT
CACGGTTTCCTACCTCCTCGGCAAGAAGGTGCGAAACCGCGTCAAAGACATGCCCTATGAGAGCGGCATCGTACCCACGG
GTGACGCGCGCCATCGGTTCAGCGTGAAATTCTATTTGGTGGGAATGCTCTTCATCCTGTTCGATATCGAAGCTATTTTC
CTGTATCCCTGGGTGGTTGTTTATCGCGATTTGAGCCGCAATGGCAGTCTGTTCGGCTTCTACGAAATGTTGACCTTCGT
GATCCTCATCCTTTCGGGATTCTTCTACATCTGGAAGAAAGGCGCGTTGGACTGGGGCGAGCCCACCGCTCGGCCGGGGC
GGAAGTAA

Upstream 100 bases:

>100_bases
GTGGCTCTCCGTTGACCACGATCTCGATCATGTTTGGTTGACACCCCTGTTTTCGAACCATTATAGTCAAATTTGGCCCC
TTCCCTACAGTTGAACTAGC

Downstream 100 bases:

>100_bases
GGAAACAAAATGCTACCCGAGAATCTGAAAGAGAATGCCGTGGCCGCCGCGGTGGAGGCCTTTGACGCCGATGCCGTGCG
CGGTGGTAAGGTGACGTTCG

Product: NADH-ubiquinone/plastoquinone oxidoreductase subunit 3

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MPKSYTELYFPILLQAVIAMGLAAGLLTVSYLLGKKVRNRVKDMPYESGIVPTGDARHRFSVKFYLVGMLFILFDIEAIF
LYPWVVVYRDLSRNGSLFGFYEMLTFVILILSGFFYIWKKGALDWGEPTARPGRK

Sequences:

>Translated_135_residues
MPKSYTELYFPILLQAVIAMGLAAGLLTVSYLLGKKVRNRVKDMPYESGIVPTGDARHRFSVKFYLVGMLFILFDIEAIF
LYPWVVVYRDLSRNGSLFGFYEMLTFVILILSGFFYIWKKGALDWGEPTARPGRK
>Mature_134_residues
PKSYTELYFPILLQAVIAMGLAAGLLTVSYLLGKKVRNRVKDMPYESGIVPTGDARHRFSVKFYLVGMLFILFDIEAIFL
YPWVVVYRDLSRNGSLFGFYEMLTFVILILSGFFYIWKKGALDWGEPTARPGRK

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=125, Percent_Identity=40, Blast_Score=96, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOA_SOLUE (Q02CU2)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_821409.1
- STRING:   Q02CU2
- GeneID:   4424021
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_0109
- NMPDR:   fig|234267.9.peg.103
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- OMA:   GRFPIKY
- PhylomeDB:   Q02CU2
- ProtClustDB:   CLSK774518
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 15504; Mature: 15372

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x134dc328)-; HASH(0x13f9bde8)-; HASH(0x13f93774)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKSYTELYFPILLQAVIAMGLAAGLLTVSYLLGKKVRNRVKDMPYESGIVPTGDARHRF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
SVKFYLVGMLFILFDIEAIFLYPWVVVYRDLSRNGSLFGFYEMLTFVILILSGFFYIWKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
GALDWGEPTARPGRK
CCCCCCCCCCCCCCH
>Mature Secondary Structure 
PKSYTELYFPILLQAVIAMGLAAGLLTVSYLLGKKVRNRVKDMPYESGIVPTGDARHRF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
SVKFYLVGMLFILFDIEAIFLYPWVVVYRDLSRNGSLFGFYEMLTFVILILSGFFYIWKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
GALDWGEPTARPGRK
CCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA