Click here to switch to the map view.

The map label for this gene is kdpE [H]

Identifier: 116619216

GI number: 116619216

Start: 102171

End: 102857

Strand: Direct

Name: kdpE [H]

Synonym: Acid_0071

Alternate gene names: 116619216

Gene position: 102171-102857 (Clockwise)

Preceding gene: 116619215

Following gene: 116619217

Centisome position: 1.03

GC content: 62.59

Gene sequence:

>687_bases
TTGAGCATCGCAAAAATCCTGGTCGTGGACGACGATCCGCAGATCCGCCGCGTCATGAAAGCGACGCTGGTGGGACACAG
CTATGAGGTGATCGAGGCGCGCACAGGCGAAGATGCGCTCGAAGCGCTGCCGCACGAGATGCCGAACCTGGTGCTGCTCG
ATATGAACATGCCCGGCATGGGCGGCCTGGAGACTTGCCGCGCGATCCGCTCCGGAACCGACATTCCGGTGATCATTCTC
TCCGTCCGCAATACCGAAAAAGACAAAGTGGCGGCGCTCGACGCCGGCGCCGACGATTACGTCACCAAGCCTTTCGGCAT
TGAAGAGCTGCTGGCCCGCATCCGCGCCGCGCTGCGCCGTTCGCCCTCCGGCCCCGATGGCGGCCCTCACGGCTTCACCG
CCTCCAATCTCGAGATCGATTTCGACGCGCGCCGTGTCCACGCCAACGGCAAGGATGTTCGCCTCACGCCCAAGGAATTC
GAAATGCTTCGCTACCTGGTGGCGCACAGCGGACGCCCCGTGACCCATCGCGAACTGCTGCAGGCCGTGTGGGGGCCAGA
CTACGGCGATGAGCCCGAATACCTGCGCGTCTTCATCAATCAACTGCGCAAGAAAATCGAGGCTAACCCCAGCAAGCCAA
AGTTTATCCTCACCGAGCCCTGGGTCGGCTATCGCTTCGCGGGATGA

Upstream 100 bases:

>100_bases
GCATCATTGAAGCTCACGGCGAAAAGATCTGGGTGGAGAGCGAGCCCGAGCACGGTTCGGCCTTCTATTTCTCTTTGCCG
CTAGCCGAAGGCAGGGACGC

Downstream 100 bases:

>100_bases
CCACTTAACTCAATCCTGATCGTTTCTTTACGACTTCTTTAGGGGTCCGCTTCTACCCTTGAGTCATGGAAAGTCGTGGC
GAGCTACGAATTGATCCAGG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSIAKILVVDDDPQIRRVMKATLVGHSYEVIEARTGEDALEALPHEMPNLVLLDMNMPGMGGLETCRAIRSGTDIPVIIL
SVRNTEKDKVAALDAGADDYVTKPFGIEELLARIRAALRRSPSGPDGGPHGFTASNLEIDFDARRVHANGKDVRLTPKEF
EMLRYLVAHSGRPVTHRELLQAVWGPDYGDEPEYLRVFINQLRKKIEANPSKPKFILTEPWVGYRFAG

Sequences:

>Translated_228_residues
MSIAKILVVDDDPQIRRVMKATLVGHSYEVIEARTGEDALEALPHEMPNLVLLDMNMPGMGGLETCRAIRSGTDIPVIIL
SVRNTEKDKVAALDAGADDYVTKPFGIEELLARIRAALRRSPSGPDGGPHGFTASNLEIDFDARRVHANGKDVRLTPKEF
EMLRYLVAHSGRPVTHRELLQAVWGPDYGDEPEYLRVFINQLRKKIEANPSKPKFILTEPWVGYRFAG
>Mature_227_residues
SIAKILVVDDDPQIRRVMKATLVGHSYEVIEARTGEDALEALPHEMPNLVLLDMNMPGMGGLETCRAIRSGTDIPVIILS
VRNTEKDKVAALDAGADDYVTKPFGIEELLARIRAALRRSPSGPDGGPHGFTASNLEIDFDARRVHANGKDVRLTPKEFE
MLRYLVAHSGRPVTHRELLQAVWGPDYGDEPEYLRVFINQLRKKIEANPSKPKFILTEPWVGYRFAG

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=41.5178571428571, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=33.920704845815, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=33.6283185840708, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=30.7692307692308, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790552, Length=207, Percent_Identity=39.1304347826087, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=30.2631578947368, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=30.8035714285714, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=30.9417040358744, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=30.316742081448, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI2367329, Length=209, Percent_Identity=35.8851674641148, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=30.6666666666667, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=27.1551724137931, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=29.4871794871795, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790860, Length=229, Percent_Identity=27.5109170305677, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788550, Length=119, Percent_Identity=35.2941176470588, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790299, Length=114, Percent_Identity=36.8421052631579, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790437, Length=133, Percent_Identity=36.0902255639098, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788521, Length=120, Percent_Identity=38.3333333333333, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788191, Length=117, Percent_Identity=37.6068376068376, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788222, Length=114, Percent_Identity=35.0877192982456, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI145693157, Length=104, Percent_Identity=35.5769230769231, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788905, Length=124, Percent_Identity=33.0645161290323, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1787473, Length=167, Percent_Identity=34.1317365269461, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25398; Mature: 25266

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIAKILVVDDDPQIRRVMKATLVGHSYEVIEARTGEDALEALPHEMPNLVLLDMNMPGM
CCCEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCEEEEECCCCCC
GGLETCRAIRSGTDIPVIILSVRNTEKDKVAALDAGADDYVTKPFGIEELLARIRAALRR
CHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHC
SPSGPDGGPHGFTASNLEIDFDARRVHANGKDVRLTPKEFEMLRYLVAHSGRPVTHRELL
CCCCCCCCCCCCCCCCEEEECCCEEEECCCCCEEECHHHHHHHHHHHHHCCCCCCHHHHH
QAVWGPDYGDEPEYLRVFINQLRKKIEANPSKPKFILTEPWVGYRFAG
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECC
>Mature Secondary Structure 
SIAKILVVDDDPQIRRVMKATLVGHSYEVIEARTGEDALEALPHEMPNLVLLDMNMPGM
CCEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCEEEEECCCCCC
GGLETCRAIRSGTDIPVIILSVRNTEKDKVAALDAGADDYVTKPFGIEELLARIRAALRR
CHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHC
SPSGPDGGPHGFTASNLEIDFDARRVHANGKDVRLTPKEFEMLRYLVAHSGRPVTHRELL
CCCCCCCCCCCCCCCCEEEECCCEEEECCCCCEEECHHHHHHHHHHHHHCCCCCCHHHHH
QAVWGPDYGDEPEYLRVFINQLRKKIEANPSKPKFILTEPWVGYRFAG
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]