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The map label for this gene is clpX

Identifier: 116517127

GI number: 116517127

Start: 1418958

End: 1420190

Strand: Reverse

Name: clpX

Synonym: SPD_1399

Alternate gene names: 116517127

Gene position: 1420190-1418958 (Counterclockwise)

Preceding gene: 116516044

Following gene: 116515393

Centisome position: 69.41

GC content: 43.15

Gene sequence:

>1233_bases
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTGCCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGACGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTACCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAGTACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATCATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Upstream 100 bases:

>100_bases
CTCCTTTGGTTAAATGCCTTTACCAATCTGGTCAATAGTATTCATGCTTTTTACATGACCTTATTTTAGATAGAATGACA
GTATAGAATGGAAGGAAATC

Downstream 100 bases:

>100_bases
AGGTGACTATGGAACTTAACACACACAATGCTGAAATCTTGCTCAGTGCAGCTAATAAGTCCCACTATCCGCAGGATGAA
CTGCCAGAGATTGCCCTAGC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Sequences:

>Translated_410_residues
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA
>Mature_409_residues
STNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRA
KRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVDG
TDKPILETA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=324, Percent_Identity=48.7654320987654, Blast_Score=307, Evalue=1e-83,
Organism=Escherichia coli, GI1786642, Length=415, Percent_Identity=58.7951807228916, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI1790366, Length=211, Percent_Identity=33.175355450237, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71982905, Length=320, Percent_Identity=44.6875, Blast_Score=278, Evalue=5e-75,
Organism=Caenorhabditis elegans, GI71982908, Length=320, Percent_Identity=44.6875, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=405, Percent_Identity=37.037037037037, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI71988660, Length=253, Percent_Identity=39.1304347826087, Blast_Score=172, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6319704, Length=430, Percent_Identity=39.7674418604651, Blast_Score=266, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24648291, Length=320, Percent_Identity=48.75, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI24648289, Length=320, Percent_Identity=48.75, Blast_Score=308, Evalue=5e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_STRP2 (Q04JH9)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816859.1
- ProteinModelPortal:   Q04JH9
- STRING:   Q04JH9
- EnsemblBacteria:   EBSTRT00000019894
- GeneID:   4442365
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1399
- eggNOG:   COG1219
- GeneTree:   EBGT00050000026952
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 45799; Mature: 45668

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSE
CCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGP
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEC
TGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENILLKLLQVADFNIERAERGI
CCCCHHHHHHHHHHHCCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHCCE
IYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
EEHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPEL
CCEEEEECCCHHHHHHHHHHHHCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
IGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIE
HHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHH
RKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVDGTDKPILETA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHCCCCCCCCCCCC
>Mature Secondary Structure 
STNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSE
CCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGP
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEC
TGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENILLKLLQVADFNIERAERGI
CCCCHHHHHHHHHHHCCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHCCE
IYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
EEHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPEL
CCEEEEECCCHHHHHHHHHHHHCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHH
IGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIE
HHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHH
RKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVDGTDKPILETA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA