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The map label for this gene is gpmA [H]

Identifier: 116516661

GI number: 116516661

Start: 1485981

End: 1486673

Strand: Reverse

Name: gpmA [H]

Synonym: SPD_1468

Alternate gene names: 116516661

Gene position: 1486673-1485981 (Counterclockwise)

Preceding gene: 116515642

Following gene: 116515332

Centisome position: 72.66

GC content: 41.99

Gene sequence:

>693_bases
ATGGTAAAATTGGTTTTTGCTCGCCACGGTGAGTCTGAATGGAACAAAGCTAACCTTTTCACTGGTTGGGCTGATGTTGA
TTTGTCTGAAAAAGGTACACAACAAGCGATTGACGCTGGTAAATTGATCAAAGAAGCTGGTATCGAATTTGACCAAGCTT
ACACTTCAGTATTGAAACGTGCTATCAAAACAACTAACTTGGCTCTTGAAGCTTCTGACCAATTATGGGTTCCAGTTGAA
AAATCATGGCGCTTGAACGAACGTCACTACGGTGGTTTGACTGGTAAAAACAAAGCTGAAGCTGCTGAACAATTTGGTGA
TGAGCAAGTTCACATCTGGCGTCGTTCATACGATGTATTGCCTCCAAATATGGACCGTGATGATGAGCACTCAGCTCACA
CAGACCGTCGTTATGCTTCACTTGACGACTCAGTAATCCCAGATGCTGAAAACTTGAAAGTGACTTTGGAACGTGCTCTT
CCATTCTGGGAAGATAAAATCGCTCCAGCTCTTAAAGATGGTAAAAACGTATTCGTAGGAGCTCACGGTAACTCAATCCG
TGCCCTTGTAAAACACATCAAAGGTTTGTCAGATGATGAGATCATGGACGTGGAAATCCCTAACTTCCCACCATTGGTAT
TCGAATTCGATGAAAAATTGAACGTTGTTTCTGAATACTACCTTGGAAAATAA

Upstream 100 bases:

>100_bases
TTTCCTTTTTGGTTTTGACTAGCTTTTTTGTGAAAAATTGTGTAAAATAGAATAGATAAACGAGGGGAAACCTCGGAAAA
TTTAAAGGAGAATCCATCTA

Downstream 100 bases:

>100_bases
AAAATTGTAAGCCTAGGATTGATTTCTAGGCTTTTTATGTTAGTATGGAAGTATGATAAGGAATAAAAAACAAGATTATG
TACTGGCCTACAAGCAACCA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVE
KSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK

Sequences:

>Translated_230_residues
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVE
KSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK
>Mature_230_residues
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVE
KSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=220, Percent_Identity=53.6363636363636, Blast_Score=256, Evalue=1e-68,
Organism=Homo sapiens, GI4505753, Length=223, Percent_Identity=52.4663677130045, Blast_Score=239, Evalue=2e-63,
Organism=Homo sapiens, GI71274132, Length=223, Percent_Identity=50.2242152466368, Blast_Score=226, Evalue=1e-59,
Organism=Homo sapiens, GI4502445, Length=232, Percent_Identity=46.1206896551724, Blast_Score=221, Evalue=3e-58,
Organism=Homo sapiens, GI40353764, Length=232, Percent_Identity=46.1206896551724, Blast_Score=221, Evalue=3e-58,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=55.2795031055901, Blast_Score=169, Evalue=2e-42,
Organism=Escherichia coli, GI1786970, Length=229, Percent_Identity=55.4585152838428, Blast_Score=270, Evalue=6e-74,
Organism=Saccharomyces cerevisiae, GI6322697, Length=229, Percent_Identity=53.2751091703057, Blast_Score=254, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6320183, Length=283, Percent_Identity=31.095406360424, Blast_Score=134, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6324516, Length=276, Percent_Identity=32.6086956521739, Blast_Score=128, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6324857, Length=195, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646216, Length=231, Percent_Identity=51.9480519480519, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI85725270, Length=231, Percent_Identity=51.0822510822511, Blast_Score=231, Evalue=4e-61,
Organism=Drosophila melanogaster, GI85725272, Length=231, Percent_Identity=51.0822510822511, Blast_Score=231, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24650981, Length=231, Percent_Identity=51.0822510822511, Blast_Score=231, Evalue=4e-61,
Organism=Drosophila melanogaster, GI28571815, Length=220, Percent_Identity=40, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI28571817, Length=220, Percent_Identity=40, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24648979, Length=220, Percent_Identity=40, Blast_Score=172, Evalue=2e-43,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 26051; Mature: 26051

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDQAYTSVLKR
CEEEEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVL
HHHHHCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCC
PPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVG
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEHHHCCCHHHHHHCHHHHCCCEEEEE
AHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK
CCCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHCCC
>Mature Secondary Structure
MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDQAYTSVLKR
CEEEEEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVL
HHHHHCEEEECCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCC
PPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVG
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEEHHHCCCHHHHHHCHHHHCCCEEEEE
AHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDEKLNVVSEYYLGK
CCCCHHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA