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The map label for this gene is atpB

Identifier: 116516382

GI number: 116516382

Start: 1354876

End: 1355592

Strand: Reverse

Name: atpB

Synonym: SPD_1340

Alternate gene names: 116516382

Gene position: 1355592-1354876 (Counterclockwise)

Preceding gene: 116515363

Following gene: 116515510

Centisome position: 66.25

GC content: 35.84

Gene sequence:

>717_bases
ATGGAAGAAAGTATTAATCCAATCATCTCTATTGGTCCTGTTATCTTCAATCTGACTATGTTAGCCATGACTTTGTTGAT
TGTGGGAGTTATTTTTGTCTTTATTTATTGGGCAAGCCGCAATATGACCTTGAAACCCAAAGGAAAGCAAAATGTACTTG
AGTATGTCTATGACTTTGTTATTGGATTTACAGAACCTAACATTGGTTCGCGCTACATGAAAGATTACTCACTCTTTTTC
CTTTGTTTATTCCTTTTCATGGTGATTGCCAATAACCTTGGCTTAATGACAAAGCTTCAAACGATCGATGGGACTAACTG
GTGGAGTTCGCCAACCGCTAATTTACAGTATGACTTAACCTTATCTTTTCTTGTCATTTTGTTGACACATATAGAAAGCG
TTCGTCGTCGTGGATTTAAAAAAAGTATAAAATCTTTTATGAGTCCTGTTTTTGTCATACCGATGAATATCTTGGAAGAA
TTTACAAACTTCTTATCTTTGGCTTTGCGGATTTTTGGGAATATCTTTGCAGGAGAGGTCATGACGAGTTTGTTACTTCT
TCTTTCCCACCAAGCTATTTATTGGTATCCAGTAGCCTTTGGAGCTAATTTGGCTTGGACTGCATTTTCTGTCTTTATTT
CCTGCATCCAAGCTTATGTTTTTACTCTTTTGACATCTGTGTATTTAGGGAATAAGATTAATATTGAAGAGGAATAG

Upstream 100 bases:

>100_bases
TTAGGTGTTGCCTTTATTGAAGGAACTTTCTTTGTAACTCTTGTCTTCTCATTTATTATCAAATAAATACATGGAACGAG
AAGAAAAGGGAGGATTTTAG

Downstream 100 bases:

>100_bases
AAAGGAGTAACTGATGCACGTAACAGTAGGTGAATTAATTGGTAATTTTATTTTAATCACTGGCTCTTTTATTCTTTTGC
TAGTCTTGATTAAAAAATTT

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTLKPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFF
LCLFLFMVIANNLGLMTKLQTIDGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQAYVFTLLTSVYLGNKINIEEE

Sequences:

>Translated_238_residues
MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTLKPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFF
LCLFLFMVIANNLGLMTKLQTIDGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQAYVFTLLTSVYLGNKINIEEE
>Mature_238_residues
MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTLKPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFF
LCLFLFMVIANNLGLMTKLQTIDGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQAYVFTLLTSVYLGNKINIEEE

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_STRP2 (Q04HT4)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816802.1
- ProteinModelPortal:   Q04HT4
- SMR:   Q04HT4
- STRING:   Q04HT4
- EnsemblBacteria:   EBSTRT00000019228
- GeneID:   4443045
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1340
- eggNOG:   COG0356
- GeneTree:   EBGT00050000028075
- HOGENOM:   HBG734175
- OMA:   LHGQVFL
- ProtClustDB:   PRK05815
- HAMAP:   MF_01393
- InterPro:   IPR000568
- Gene3D:   G3DSA:1.20.120.220
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 27209; Mature: 27209

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1b6cff20)-; HASH(0x1c2c4928)-; HASH(0x1ad31edc)-; HASH(0x1bc6b024)-; HASH(0x1bd6e5e8)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTLKPKGKQNVLEYVYDFV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHH
IGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTIDGTNWWSSPTANLQYDLT
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCEEEHHH
LSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEEFTNFLSLALRIFGNIFAGEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQAYVFTLLTSVYLGNKINIEEE
HHHHHHHHHCCHHEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
>Mature Secondary Structure
MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTLKPKGKQNVLEYVYDFV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHH
IGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTIDGTNWWSSPTANLQYDLT
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCEEEHHH
LSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEEFTNFLSLALRIFGNIFAGEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQAYVFTLLTSVYLGNKINIEEE
HHHHHHHHHCCHHEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA