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The map label for this gene is capA [H]

Identifier: 116515911

GI number: 116515911

Start: 1307053

End: 1307565

Strand: Reverse

Name: capA [H]

Synonym: SPD_1282

Alternate gene names: 116515911

Gene position: 1307565-1307053 (Counterclockwise)

Preceding gene: 116516365

Following gene: 116515589

Centisome position: 63.9

GC content: 39.18

Gene sequence:

>513_bases
ATGGATGCTATTAAGGAGGCAGGTTATCATGTGCTGGATTTAGCTCATAATCATATTTTGGATTCGCAAATTGAGGGAGT
TATTTCAACGGCCGATATTATTGAGAAAGCTGGAATCACTCCAATCGGAGTTTATACGCACGAACCACGTGATCAGGCTC
CGCTGGTCATTAAGGAAGTGAATGGTATCAAGGTTGCATTGTTAGCCTATTCCTATGGTTTCAATGGAATTGAGCAGTAT
ATTTCTCAGGAAGACTATAATCGTTATCTTTCAGATTTAAACGAAGATAAGATGAAGGTTGAAATTGAACGGGCAGAGAA
GGAAGCAGATATCACCATTATCATGCTTCAGATGGGTGTTGAGTATCGATTGGAACCAACTGAAGAACAAAAAGCTCTTT
ATCACAAGATGATCGATTTGGGAGCGGATATTATCTTTGGAGGGCATCCTCACGTTGTTGAACCATCTGAAACGGTTGAA
AAAGATGGAGATAAGAAACTCATTATCTATTAA

Upstream 100 bases:

>100_bases
GGACTAAGCAGCAGATTTAGCTATTGGTGATTTTGAAGGAACCATTAATAAGGATCATTATTTAGCGGGTTATCTTCTCT
TTAATGCTCCTGTTGAAGTT

Downstream 100 bases:

>100_bases
ATGGGGAACTTCATTTCCAATCAACGAATTGAATCTATGGGAGATGAAGAGAATGCTAAGTGGACTGAACGTGGTGTTCT
CATGGATGTCACCATCAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MDAIKEAGYHVLDLAHNHILDSQIEGVISTADIIEKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYGFNGIEQY
ISQEDYNRYLSDLNEDKMKVEIERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDLGADIIFGGHPHVVEPSETVE
KDGDKKLIIY

Sequences:

>Translated_170_residues
MDAIKEAGYHVLDLAHNHILDSQIEGVISTADIIEKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYGFNGIEQY
ISQEDYNRYLSDLNEDKMKVEIERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDLGADIIFGGHPHVVEPSETVE
KDGDKKLIIY
>Mature_170_residues
MDAIKEAGYHVLDLAHNHILDSQIEGVISTADIIEKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYGFNGIEQY
ISQEDYNRYLSDLNEDKMKVEIERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDLGADIIFGGHPHVVEPSETVE
KDGDKKLIIY

Specific function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC [H]

COG id: COG2843

COG function: function code M; Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CapA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019079 [H]

Pfam domain/function: PF09587 PGA_cap [H]

EC number: NA

Molecular weight: Translated: 19199; Mature: 19199

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAIKEAGYHVLDLAHNHILDSQIEGVISTADIIEKAGITPIGVYTHEPRDQAPLVIKEV
CCCHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEC
NGIKVALLAYSYGFNGIEQYISQEDYNRYLSDLNEDKMKVEIERAEKEADITIIMLQMGV
CCEEEEEEEECCCCHHHHHHHCHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCC
EYRLEPTEEQKALYHKMIDLGADIIFGGHPHVVEPSETVEKDGDKKLIIY
CEECCCCHHHHHHHHHHHHCCCCEEECCCCCEECCHHHHHCCCCCEEEEC
>Mature Secondary Structure
MDAIKEAGYHVLDLAHNHILDSQIEGVISTADIIEKAGITPIGVYTHEPRDQAPLVIKEV
CCCHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEC
NGIKVALLAYSYGFNGIEQYISQEDYNRYLSDLNEDKMKVEIERAEKEADITIIMLQMGV
CCEEEEEEEECCCCHHHHHHHCHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEECCC
EYRLEPTEEQKALYHKMIDLGADIIFGGHPHVVEPSETVEKDGDKKLIIY
CEECCCCHHHHHHHHHHHHCCCCEEECCCCCEECCHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2536679; 10475962; 12004073 [H]