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The map label for this gene is codY

Identifier: 116515749

GI number: 116515749

Start: 1430267

End: 1431055

Strand: Reverse

Name: codY

Synonym: SPD_1412

Alternate gene names: 116515749

Gene position: 1431055-1430267 (Counterclockwise)

Preceding gene: 116516011

Following gene: 116516385

Centisome position: 69.94

GC content: 40.3

Gene sequence:

>789_bases
ATGGCACATTTATTAGAAAAAACTAGAAAAATTACATCAATTTTGAAACGCTCAGAGGAGCAGTTGCAGGATGAGCTCCC
TTACAACGCTATTACGCGTCAGTTAGCGGATATTATTCATTGCAATGCCTGCATTATCAATAGTAAGGGACGTCTGCTTG
GCTATTTTATGCGTTATAAAACAAATACAGATCGCGTAGAGCAATTCTTCCAAACTAAGATTTTCCCAGATGACTACGTT
CAAGGGGCTAATATGATTTACGAAACAGAAGCAAACTTGCCTGTTGAGCATGATATGAGTATTTTCCCTGTTGAGAGTAG
AGATGATTTTCCAGATGGCTTGACGACTATTGCACCGATTCATGTATCGGGGATTCGCCTTGGTTCTTTGATTATTTGGC
GTAATGATAAAAAATTCGAAGATGAGGACTTGGTTCTTGTTGAGATTGCCAGTACCGTTGTTGGGATTCAGCTTCTTAAC
TTCCAACGTGAAGAAGATGAGAAAAATATTCGTCGTCGTACTGCTGTCACCATGGCGGTCAATACCCTTTCTTACTCCGA
ACTCCGTGCTGTTTCAGCAATTTTAGGGGAATTAAATGGAAATGAAGGGCAGTTGACTGCGTCAGTGATTGCAGATCGTA
TCGGAATCACTCGCTCTGTGATTGTCAATGCTCTTCGTAAACTTGAGTCTGCGGGGATTATTGAAAGTCGCTCACTTGGA
ATGAAGGGAACCTATCTTAAGGTCTTGATTTCAGATATTTTTGAAGAAGTGAAGAAAAGAGATTACTAA

Upstream 100 bases:

>100_bases
AAATTGTAAGTCAATGCAAGTCAATAAGGAATTTTCAGATAATTATTGAAAAAGAGACGTTTTTATGTTATAATGATAGC
GATTAAATTCGAGGTGAAAA

Downstream 100 bases:

>100_bases
TGACAAAGGCTTTAATTTCGATTGATTATACAGAAGATTTTGTTGCTGATAGTGGGAAGCTGACAGCAGGTGCTCCAGCT
CAGGCGATTTCGGATGCCAT

Product: transcriptional repressor CodY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYV
QGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLISDIFEEVKKRDY

Sequences:

>Translated_262_residues
MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYV
QGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLISDIFEEVKKRDY
>Mature_261_residues
AHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQ
GANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLNF
QREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLGM
KGTYLKVLISDIFEEVKKRDY

Specific function: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of

COG id: COG4465

COG function: function code K; Pleiotropic transcriptional repressor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CodY family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CODY_STRP2 (Q04JG7)

Other databases:

- EMBL:   CP000410
- RefSeq:   YP_816871.1
- ProteinModelPortal:   Q04JG7
- STRING:   Q04JG7
- EnsemblBacteria:   EBSTRT00000020422
- GeneID:   4442404
- GenomeReviews:   CP000410_GR
- KEGG:   spd:SPD_1412
- eggNOG:   COG4465
- GeneTree:   EBGT00050000028138
- HOGENOM:   HBG304760
- OMA:   HIFEELD
- ProtClustDB:   PRK04158
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_00621
- InterPro:   IPR014154
- InterPro:   IPR010312
- InterPro:   IPR013198
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF011572
- TIGRFAMs:   TIGR02787

Pfam domain/function: PF06018 CodY; PF08222 HTH_CodY

EC number: NA

Molecular weight: Translated: 29757; Mature: 29625

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYK
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHC
TNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPI
CCHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCCEEEEE
HVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLNFQREEDEKNIRRRTAVTMAV
EECCEEEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
NTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEECCCCC
MKGTYLKVLISDIFEEVKKRDY
CCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYK
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHC
TNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPI
CCHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCCEEEEE
HVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLNFQREEDEKNIRRRTAVTMAV
EECCEEEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
NTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEECCCCC
MKGTYLKVLISDIFEEVKKRDY
CCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA