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The map label for this gene is hprK [H]

Identifier: 116515609

GI number: 116515609

Start: 1272485

End: 1273420

Strand: Reverse

Name: hprK [H]

Synonym: SPD_1244

Alternate gene names: 116515609

Gene position: 1273420-1272485 (Counterclockwise)

Preceding gene: 116517095

Following gene: 116515924

Centisome position: 62.24

GC content: 43.7

Gene sequence:

>936_bases
ATGTCGGTTTTAGTAAAAGAAGTGATTGAAAAGCTTAGACTAGACATTGTCTATGGTGAACCAGAATTGCTTGAAAAGGA
AATCAATATAGCGGATATTACGCGACCTGGTCTTGAAATGACAGGCTATTTTGACTACTATACACCAGAGCGGATTCAAC
TTTTGGGGATGAAGGAGTGGTCTTATCTGATCAGCATGCCTTCCAACAGCCGTTATGAAGTTTTGAAAAAAATGTTTCTA
CCTGAGACACCAGCAGTCATTGTTGCCCGTGGTTTGGTGGTTCCAGAGGAGATGTTAAAGGCTGCTAGAGAATGTAAGAT
TGCTATTTTAACCAGCCGTGCAGCTACCAGTCGTTTATCTGGAGAGTTATCTAGCTATCTGGATTCTCGTTTGGCAGAAC
GTACCAGTGTGCACGGTGTCTTGATGGATATTTATGGGATGGGCGTCTTGATTCAGGGAGATAGTGGAATTGGTAAGAGT
GAGACAGGTCTTGAGCTTGTCAAACGTGGTCACCGTTTGGTAGCCGATGACCGTGTCGATATCTTTGCCAAGGATGAGAT
TACTCTCTGGGGTGAACCAGCTGAAATTTTGAAACACTTGATTGAAATTCGTGGGGTTGGTATTATCGATGTTATGAGTC
TCTACGGTGCGAGTGCTGTCAAGGATTCTTCACAGGTTCAGCTTGCTGTCTATTTGGAAAATTACGATACGCATAAGACC
TTTGATCGTCTTGGAAACAATGCAGAGGAACTTGAAGTTTCTGGCGTAGCCATTCCTCGTATTCGTATTCCAGTTAAAAC
AGGTCGTAATATCTCTGTTGTGATTGAGGCAGCTGCCATGAATTATCGTGCCAAGGAAATGGGCTTTGATGCGACCCGTT
TGTTCGACGAACGACTGACAAGTCTCATCGCTCGAAATGAGGTGCAAAATGCTTGA

Upstream 100 bases:

>100_bases
CTTTTTCTTTTAAATAAATACTCCAAAGCCTGCAAAAATCTGAAACTTCCTCCTACAATTTGATATAATAGAGAGAAGAA
CTCATTTGAAGGAGGAAATG

Downstream 100 bases:

>100_bases
TCCAATTGCTATTCAACTAGGACCCCTAGCCATTCGTTGGTATGCCTTATGTATTGTGACAGGCTTGATTCTTGCGGTTT
ATTTGACCATGAAAGAAGCA

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYFDYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFL
PETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKT
FDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA

Sequences:

>Translated_311_residues
MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYFDYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFL
PETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKT
FDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA
>Mature_310_residues
SVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYFDYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLP
ETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKSE
TGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKTF
DRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 34740; Mature: 34608

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYFDYYTPERIQLLGMKEW
CCHHHHHHHHHHCEEEEECCHHHHHHCCCEEECCCCCCCEEEEECCCCCCCEEEEECCCC
SYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLS
EEEEECCCCCHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHCEEEEEECHHHHHHHH
GELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVD
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHCCCEEEECCCEE
IFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKT
EEECCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCHHCCCCCCEEEEEEEECCCCHHH
FDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLT
HHHHCCCHHHEEECCEEECEEEEEECCCCCEEEEEEEHHHCCHHHHHCCHHHHHHHHHHH
SLIARNEVQNA
HHHHHHHCCCC
>Mature Secondary Structure 
SVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYFDYYTPERIQLLGMKEW
CHHHHHHHHHHCEEEEECCHHHHHHCCCEEECCCCCCCEEEEECCCCCCCEEEEECCCC
SYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAARECKIAILTSRAATSRLS
EEEEECCCCCHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHCEEEEEECHHHHHHHH
GELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKSETGLELVKRGHRLVADDRVD
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHCCCEEEECCCEE
IFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGASAVKDSSQVQLAVYLENYDTHKT
EEECCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCHHCCCCCCEEEEEEEECCCCHHH
FDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIEAAAMNYRAKEMGFDATRLFDERLT
HHHHCCCHHHEEECCEEECEEEEEECCCCCEEEEEEEHHHCCHHHHHCCHHHHHHHHHHH
SLIARNEVQNA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]