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The map label for this gene is pgm [H]

Identifier: 116515604

GI number: 116515604

Start: 1341179

End: 1342897

Strand: Direct

Name: pgm [H]

Synonym: SPD_1326

Alternate gene names: 116515604

Gene position: 1341179-1342897 (Clockwise)

Preceding gene: 116516831

Following gene: 116516657

Centisome position: 65.55

GC content: 43.28

Gene sequence:

>1719_bases
ATGTCTTACCAAGAAAATTACCAGAAATGGGTTGATTTTGTGGAGCTTCCTGACTACCTTCGTCAAGATTTGGAAAATAT
GGACGAAAAAACTAAGGAAGATGCCTTCTATACAAATCTTGAATTTGGTACTGCAGGTATGCGTGGCTTGGTTGGTGCTG
GTACAAACCGTATCAACATCTACGTTGTTCGCCAAGCTACTGAAGGATTGGCTCGTTTGATTGAGTCAAAAGGTGGAAAC
GAGAAAGAACGCGGTGTAGCAATTGCCTACGATAGCCGTCACTTCTCACCTGAGTTTGCCTTTGAATCTGCGGCAGTTCT
TGCTAAACACGGCATCAAATCTTACGTATTTGAAAGCCTTCGTCCGACTCCAGAACTATCATTTGCAGTTCGTCATCTCA
ACTGTTTCGCAGGTATCATGGTCACAGCCAGCCACAACCCTGCTCCATTTAACGGTTACAAGGTTTACGGTGAAGACGGT
GGACAAATGCCTCCACACGATGCGGACGCTTTGACTACTTATATCCGTGCAATCGAAAACCCATTTGCAGTTGAAGTTGC
TGATGTGGAAACTGAAAAAGCTTCTGGCTTGATTGAAGTTATCGGCGAAGCTGTTGACATAGAATACCTTAAAGAGGTTA
AGGACATAAACATCAACCCAGCCTTGATTGAAGAATTTGGTAAAGACATGAAGATTGTCTACACACCACTTCATGGTACT
GGTGAAATGTTGGCTCGTCGTGCTCTTGCCCAAGCAGGATTTGACTCTGTTCAAGTTGTTGAAGCGCAAGCAACTGCTGA
CCCAGACTTTTCAACTGTAACATCTCCAAACCCAGAAAGCCAAGCAGCCTTTGCCCTTGCTGAAGAACTTGGTCGTCAAG
TTGGTGCAGATGTTCTTGTCGCAACTGACCCAGACGCTGACCGTGTTGGTGTTGAAGTTCTTCAAAAAGATGGTAGCTAC
CTCAACCTTTCAGGTAACCAAATCGGTGCTATCATGGCTAAATACATCTTGGAAGCTCACAAAAACGCTGGAACTCTTCC
TGAAAATGCCGCTCTCTGCAAATCTATCGTTTCAACTGACTTGGTAACGAAGATTGCTGAAAGCTACGGCGCAACTATGT
TCAACGTCTTGACAGGTTTCAAATTTATCGCTGAAAAAATCCAAGAATTCGAAGAAAAACACAACCACACTTACATGATG
GGATTTGAAGAAAGCTTCGGTTACTTGATTAAACCATTTGTACGTGATAAAGATGCCATCCAAGCCGTTCTTGTAGTTGC
TGAACTTGCTGCCTACTACCGTTCTCGTGGTTTGACACTTGCTGACGGTATCGAAGAAATCTATAAAGAATATGGCTACT
ACGCAGAAAAAACAATCTCTGTTACTCTTTCAGGTGTCGATGGTGCTGAACAAATCAAAGCGATTATGGCTAAATTCCGC
AACAATGCTCCAACAGAATGGAACGCAACAGCTATCACTGTCGTAGAAGACTTCAAGGCACAAACTGCTACTGTTGCTGA
CGGTACTGTTACAAACTTGACAACTCCTCCAAGTGATGTGTTGAAATACACACTTGCTGACGGTTCATGGATTGCCGTTC
GCCCTTCAGGTACAGAACCAAAAATCAAGTTCTACATTGCAGTTGTAGGGGAAACCAACGAAGAATCACAAGCTAAGATT
GCTAACATCGAAGCAGAAATCAATGCATTTGTAAAATAA

Upstream 100 bases:

>100_bases
TGGTTTGAAGAGATGTTCGAAGCAGATAAGGTTTTACTAAAACTAAAAAAAATGATATAATTAAACTGATTAAATGTTTT
AAAAATAAAGGAGAATTTGA

Downstream 100 bases:

>100_bases
AGACCTATAAAAGATGAGACCAACCAACCTCATCTTTTTTCGTATCAAATCTAAGCAATTTTAGAAACTTTATGGCATAC
TAGACTTATCAATGAAAGCG

Product: phosphoglucomutase/phosphomannomutase family protein

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGTAGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGN
EKERGVAIAYDSRHFSPEFAFESAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDININPALIEEFGKDMKIVYTPLHGT
GEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSPNPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSY
LNLSGNQIGAIMAKYILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEEKHNHTYMM
GFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKEYGYYAEKTISVTLSGVDGAEQIKAIMAKFR
NNAPTEWNATAITVVEDFKAQTATVADGTVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKI
ANIEAEINAFVK

Sequences:

>Translated_572_residues
MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGTAGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGN
EKERGVAIAYDSRHFSPEFAFESAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDININPALIEEFGKDMKIVYTPLHGT
GEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSPNPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSY
LNLSGNQIGAIMAKYILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEEKHNHTYMM
GFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKEYGYYAEKTISVTLSGVDGAEQIKAIMAKFR
NNAPTEWNATAITVVEDFKAQTATVADGTVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKI
ANIEAEINAFVK
>Mature_571_residues
SYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGTAGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNE
KERGVAIAYDSRHFSPEFAFESAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDGG
QMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDININPALIEEFGKDMKIVYTPLHGTG
EMLARRALAQAGFDSVQVVEAQATADPDFSTVTSPNPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYL
NLSGNQIGAIMAKYILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEEKHNHTYMMG
FEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKEYGYYAEKTISVTLSGVDGAEQIKAIMAKFRN
NAPTEWNATAITVVEDFKAQTATVADGTVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIA
NIEAEINAFVK

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=548, Percent_Identity=31.021897810219, Blast_Score=266, Evalue=4e-71,
Organism=Homo sapiens, GI31377548, Length=570, Percent_Identity=31.2280701754386, Blast_Score=251, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71993870, Length=564, Percent_Identity=31.9148936170213, Blast_Score=238, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI71993878, Length=308, Percent_Identity=35.0649350649351, Blast_Score=154, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6323934, Length=565, Percent_Identity=32.0353982300885, Blast_Score=209, Evalue=1e-54,
Organism=Drosophila melanogaster, GI20129809, Length=574, Percent_Identity=29.7909407665505, Blast_Score=257, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24651977, Length=477, Percent_Identity=31.2368972746331, Blast_Score=229, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24653722, Length=558, Percent_Identity=29.2114695340502, Blast_Score=218, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 62671; Mature: 62540

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGTAGMRGLVGAGTNRINI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHCCCCCEEEE
YVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFESAAVLAKHGIKSYVFESL
EEEECHHHHHHHHHHHCCCCCHHCCEEEEECCCCCCCHHHHHHHHHHHHHCHHHHHHHHC
RPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDGGQMPPHDADALTTYIRAIEN
CCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCC
PFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDININPALIEEFGKDMKIVYTPLHGT
CCEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCC
GEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSPNPESQAAFALAEELGRQVGADVLV
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
ATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAKYILEAHKNAGTLPENAALCKSIVSTD
ECCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LVTKIAESYGATMFNVLTGFKFIAEKIQEFEEKHNHTYMMGFEESFGYLIKPFVRDKDAI
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCHHHHHHHCCHHHH
QAVLVVAELAAYYRSRGLTLADGIEEIYKEYGYYAEKTISVTLSGVDGAEQIKAIMAKFR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEEEEEECCCCHHHHHHHHHHHH
NNAPTEWNATAITVVEDFKAQTATVADGTVTNLTTPPSDVLKYTLADGSWIAVRPSGTEP
CCCCCCCCCEEEEEEECCCCCEEEECCCCEECCCCCHHHHHEEEECCCCEEEEECCCCCC
KIKFYIAVVGETNEESQAKIANIEAEINAFVK
EEEEEEEEEECCCCCCCHHHEEHHHHHHHHCC
>Mature Secondary Structure 
SYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGTAGMRGLVGAGTNRINI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHCCCCCEEEE
YVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFESAAVLAKHGIKSYVFESL
EEEECHHHHHHHHHHHCCCCCHHCCEEEEECCCCCCCHHHHHHHHHHHHHCHHHHHHHHC
RPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDGGQMPPHDADALTTYIRAIEN
CCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHCC
PFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDININPALIEEFGKDMKIVYTPLHGT
CCEEEEECCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCC
GEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSPNPESQAAFALAEELGRQVGADVLV
HHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
ATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAKYILEAHKNAGTLPENAALCKSIVSTD
ECCCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LVTKIAESYGATMFNVLTGFKFIAEKIQEFEEKHNHTYMMGFEESFGYLIKPFVRDKDAI
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCHHHHHHHCCHHHH
QAVLVVAELAAYYRSRGLTLADGIEEIYKEYGYYAEKTISVTLSGVDGAEQIKAIMAKFR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEEEEEECCCCHHHHHHHHHHHH
NNAPTEWNATAITVVEDFKAQTATVADGTVTNLTTPPSDVLKYTLADGSWIAVRPSGTEP
CCCCCCCCCEEEEEEECCCCCEEEECCCCEECCCCCHHHHHEEEECCCCEEEEECCCCCC
KIKFYIAVVGETNEESQAKIANIEAEINAFVK
EEEEEEEEEECCCCCCCHHHEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]