Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 116515575

GI number: 116515575

Start: 1662445

End: 1663146

Strand: Direct

Name: galE [H]

Synonym: SPD_1648

Alternate gene names: 116515575

Gene position: 1662445-1663146 (Clockwise)

Preceding gene: 116516665

Following gene: 116515914

Centisome position: 81.25

GC content: 40.74

Gene sequence:

>702_bases
ATGACCAAAACAATTCTTGTTACAGGTGGGACTAGCTACATTGGCTCCCATACCGTTAAAGCTCTTTTAAATGCTGGTTA
TCAGGTGCATATCCTTGATAATCTCTCCACAGGAAATCGAGCGGCTGTGGATAGTCGTGCTAGCTTTAAAGAACTGGATG
TTTATGATGCTAGCGCCTTAAAGGCTTACTTAGAAGAAAATCAGATTGATGCTGTCCTCCATTATACAGGTGAAATTGTT
GTGAGCGAAAGTATTGAAAATCCAAGTAAATACTTCACTGCCAACGTTGCTGGTATGAACCAAGTTCTCAAAGTCTTATC
TGAAGTTGGCATTCAAAAAATCATGTTCTCTTCGACTGCTTCTCTCTATGGAAATAACTGTATTGACAAGCCGGTGACTG
AAGATACCCTGCTCGACCCTGTCAACCCTTATGCAGAGACAAAACTGATGGGCGAACGAATGATTTACTGGATGGCCAAT
CGCTACGACTGGAAATATGTTATTTTCCGTTACTTTAATGTTGCTGGGGCTGAAATGGATGCTTCAAACGGTCTGCGTGT
GAAAAATCCAACTCACATCATTCCAAATATCAACAAGACCGCATTGGGACAAAATGATAGCTTAAAAATATTTGGAGATG
ACTACGATACACGTGACGGTTCATGTATTCGAGATTACATTTATGTCTTGGACCTTGCATAG

Upstream 100 bases:

>100_bases
GCTGCTAAAACATTTCTAGAAATTAATTTGACTTTCCTAATAGAGTTGTTCATATCTTATTTCAATTTACTATAGTACAA
AACTAGAAAAGGAAAAAATC

Downstream 100 bases:

>100_bases
GCTCATGTTAAAGGAATGAACTACCTATTTCAAGAAGACAGTTCTTCTCAAATCTTTAACTTAGGAACTAAAAAAGGCTA
TACTATCAAAGAAATCTTTA

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTKTILVTGGTSYIGSHTVKALLNAGYQVHILDNLSTGNRAAVDSRASFKELDVYDASALKAYLEENQIDAVLHYTGEIV
VSESIENPSKYFTANVAGMNQVLKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTRDGSCIRDYIYVLDLA

Sequences:

>Translated_233_residues
MTKTILVTGGTSYIGSHTVKALLNAGYQVHILDNLSTGNRAAVDSRASFKELDVYDASALKAYLEENQIDAVLHYTGEIV
VSESIENPSKYFTANVAGMNQVLKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTRDGSCIRDYIYVLDLA
>Mature_232_residues
TKTILVTGGTSYIGSHTVKALLNAGYQVHILDNLSTGNRAAVDSRASFKELDVYDASALKAYLEENQIDAVLHYTGEIVV
SESIENPSKYFTANVAGMNQVLKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMANR
YDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTRDGSCIRDYIYVLDLA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=248, Percent_Identity=34.2741935483871, Blast_Score=157, Evalue=7e-39,
Organism=Homo sapiens, GI56118217, Length=248, Percent_Identity=34.2741935483871, Blast_Score=157, Evalue=7e-39,
Organism=Homo sapiens, GI189083684, Length=248, Percent_Identity=34.2741935483871, Blast_Score=157, Evalue=7e-39,
Organism=Homo sapiens, GI7657641, Length=229, Percent_Identity=28.3842794759825, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI42516563, Length=236, Percent_Identity=26.6949152542373, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1786974, Length=238, Percent_Identity=35.7142857142857, Blast_Score=156, Evalue=9e-40,
Organism=Escherichia coli, GI48994969, Length=248, Percent_Identity=27.8225806451613, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788353, Length=255, Percent_Identity=28.2352941176471, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71982035, Length=246, Percent_Identity=34.5528455284553, Blast_Score=143, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI71982038, Length=248, Percent_Identity=34.2741935483871, Blast_Score=142, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17539532, Length=234, Percent_Identity=26.0683760683761, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17568069, Length=237, Percent_Identity=27.4261603375527, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=247, Percent_Identity=37.6518218623482, Blast_Score=166, Evalue=4e-42,
Organism=Drosophila melanogaster, GI19923002, Length=246, Percent_Identity=34.1463414634146, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21356223, Length=234, Percent_Identity=26.4957264957265, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 25938; Mature: 25806

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTILVTGGTSYIGSHTVKALLNAGYQVHILDNLSTGNRAAVDSRASFKELDVYDASAL
CCEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHCCCCCHHHH
KAYLEENQIDAVLHYTGEIVVSESIENPSKYFTANVAGMNQVLKVLSEVGIQKIMFSSTA
HHHHHHCCCEEEEEECCEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
SLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMANRYDWKYVIFRYFNVAGAEMD
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEEECCCCCCEEEEEEEHHHCCCCCC
ASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTRDGSCIRDYIYVLDLA
CCCCEEECCCCEECCCCCHHHCCCCCCEEEECCCCCCCCCCHHEEEEEEEECC
>Mature Secondary Structure 
TKTILVTGGTSYIGSHTVKALLNAGYQVHILDNLSTGNRAAVDSRASFKELDVYDASAL
CEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCHHHCCCCCHHHH
KAYLEENQIDAVLHYTGEIVVSESIENPSKYFTANVAGMNQVLKVLSEVGIQKIMFSSTA
HHHHHHCCCEEEEEECCEEEEECCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
SLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMANRYDWKYVIFRYFNVAGAEMD
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEEEEECCCCCCEEEEEEEHHHCCCCCC
ASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTRDGSCIRDYIYVLDLA
CCCCEEECCCCEECCCCCHHHCCCCCCEEEECCCCCCCCCCHHEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]