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The map label for this gene is malC

Identifier: 116515389

GI number: 116515389

Start: 1909001

End: 1910293

Strand: Direct

Name: malC

Synonym: SPD_1935

Alternate gene names: 116515389

Gene position: 1909001-1910293 (Clockwise)

Preceding gene: 116517172

Following gene: 116517158

Centisome position: 93.3

GC content: 41.45

Gene sequence:

>1293_bases
ATGGAAAAGCAACAACCTAGTAAAGCAGCCCTGCTGTCTATCATTCCTGGGTTAGGACAGATTTACAATAAACAAAAAGC
CAAAGGTTTTATCTTCCTTGGTGTAACCATCGTATTTGTCCTTTACTTCCTAGCACTTGCAACCCCTGAATTGAGCAACC
TCATCACTCTTGGTGACAAACCAGGTCGTGATAATTCCCTCTTTATGCTGATTCGTGGTGCCTTCCATCTAATCTTTGTA
ATCGTTTATGTACTCTTTTATTTCTCAAATATCAAAGATGCACATACGATTGCAAAACGCATTAACAATGGAATTCCAGT
TCCACGCACACTCAAAGACATGATCAAAGGGATTTATGAAAATGGCTTCCCTTACCTCTTGATCATTCCATCTTATGTTG
CCATGACCTTCGCGATTATCTTCCCAGTTATCGTAACCTTGATGATCGCCTTTACCAACTACGACTTCCAACACTTGCCA
CCAAACAAGTTGTTGGACTGGGTTGGTTTGACCAACTTTACAAACATTTGGAGCTTGAGTACCTTCCGTTCTGCCTTTGG
TTCTGTTCTTTCTTGGACTATCATTTGGGCTTTGGCAGCTTCTACTTTACAAATCGTAATTGGTATCTTCACAGCTATCA
TTGCCAACCAACCATTTATCAAAGGAAAACGTATCTTTGGTGTTATTTTCCTTCTTCCTTGGGCTGTCCCAGCCTTCATC
ACTATCTTGACATTCTCAAACATGTTTAACGATAGTGTCGGTGCTATCAACACTCAAGTATTGCCAATCTTGGCTAAATT
CCTTCCTTTCCTTGATGGAGCTCTTATTCCTTGGAAAACAGACCCAACTTGGACTAAGATTGCCTTGATTATGATGCAAG
GTTGGCTCGGATTCCCATACATCTACGTTTTGACTTTGGGTATCTTGCAATCTATTCCTAACGACCTTTACGAAGCAGCT
TATATTGACGGTGCCAACGCTTGGCAAAAATTCCGCAACATCACTTTCCCAATGATTTTGGCTGTTGCGGCACCTACTTT
GATTAGCCAATACACCTTCAACTTTAACAACTTCTCTATCATGTACCTCTTCAATGGTGGAGGACCTGGTAGTGTCGGAG
GTGGAGCTGGTTCAACCGATATCTTGATCTCATGGATCTACCGTTTGACAACAGGTACATCTCCTCAATACTCAATGGCG
GCAGCTGTTACCTTGATTATCTCTATCATTGTCATCTCAATCTCTATGATCGCATTCAAGAAACTACACGCATTTGATAT
GGAGGACGTCTAA

Upstream 100 bases:

>100_bases
CAAGGGGGGTGGAAATCAAATCCCCCTTTGAATTTATCAATAGAGACACAAATAATTTAGCTTTCTTATAAAAAAGTAGT
ATCCTATGAAAGGAGTTAAT

Downstream 100 bases:

>100_bases
GATGAATAACTCAATTAAACTCAAACGTAGACTGACTCAAAGCCTTACTTACCTTTACCTGATTGGTCTATCAATTGTAA
TTATCTATCCACTGTTGATT

Product: maltodextrin ABC transporter permease

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFLALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFV
IVYVLFYFSNIKDAHTIAKRINNGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQPFIKGKRIFGVIFLLPWAVPAFI
TILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALIPWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAA
YIDGANAWQKFRNITFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTGTSPQYSMA
AAVTLIISIIVISISMIAFKKLHAFDMEDV

Sequences:

>Translated_430_residues
MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFLALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFV
IVYVLFYFSNIKDAHTIAKRINNGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQPFIKGKRIFGVIFLLPWAVPAFI
TILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALIPWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAA
YIDGANAWQKFRNITFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTGTSPQYSMA
AAVTLIISIIVISISMIAFKKLHAFDMEDV
>Mature_430_residues
MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFLALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFV
IVYVLFYFSNIKDAHTIAKRINNGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQPFIKGKRIFGVIFLLPWAVPAFI
TILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALIPWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAA
YIDGANAWQKFRNITFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTGTSPQYSMA
AAVTLIISIIVISISMIAFKKLHAFDMEDV

Specific function: Part of the binding-protein-dependent transport system for maltodextrin; probably responsible for the translocation of the substrate across the membrane

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1790465, Length=272, Percent_Identity=33.8235294117647, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1787570, Length=282, Percent_Identity=26.9503546099291, Blast_Score=88, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MALC_STRPN (P0A4N1)

Other databases:

- EMBL:   L08611
- EMBL:   AE005672
- PIR:   G95246
- RefSeq:   NP_346528.1
- ProteinModelPortal:   P0A4N1
- SMR:   P0A4N1
- EnsemblBacteria:   EBSTRT00000027121
- GeneID:   930237
- GenomeReviews:   AE005672_GR
- KEGG:   spn:SP_2109
- TIGR:   SP_2109
- GeneTree:   EBGT00050000026772
- HOGENOM:   HBG739365
- OMA:   WTLAATS
- ProtClustDB:   CLSK877194
- BioCyc:   SPNE170187-1:SP_2109-MONOMER
- InterPro:   IPR000515
- InterPro:   IPR007829

Pfam domain/function: PF00528 BPD_transp_1; PF05154 TM2

EC number: NA

Molecular weight: Translated: 47773; Mature: 47773

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1cbc2f88)-; HASH(0x1c3d0e38)-; HASH(0x1d2f8b44)-; HASH(0x1d26b834)-; HASH(0x1d04c210)-; HASH(0x1bdd8af8)-; HASH(0x1c73cc3c)-; HASH(0x1c973b24)-; HASH(0x1c4c88b0)-; HASH(0x1cf7b038)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCH
>Mature Secondary Structure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HHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8478935; 11463916