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The map label for this gene is ycsN [H]

Identifier: 116496046

GI number: 116496046

Start: 2600571

End: 2601509

Strand: Direct

Name: ycsN [H]

Synonym: LSEI_2618

Alternate gene names: 116496046

Gene position: 2600571-2601509 (Clockwise)

Preceding gene: 116496040

Following gene: 116496047

Centisome position: 89.82

GC content: 48.88

Gene sequence:

>939_bases
ATGAAAATGATTGATCTAGGCCGTTCTGGTCTGCACGCTTCTGCCATTGCGTTAGGTGTTATGCGTTTGCCGAATCTCGA
TCGGCCGCGAGCAACCGAACTACTTGATGCTGCTTATGACGTCGGCATTAACTTTTTTGACAATGCTGATGTTTACAGCA
ATGGTAAAGCTGAACAGCTTTTTGGCGATGCGTTGAAGAAGGCCAGCTTTACACGTGATCAAGTCCTGATTCAGACTAAG
GTCGGTATCGTCAATGATCGAAAAGCGACCCATCGCTATGATTTCTCCAAAGAGCATATCGTGGATGCTGTCAATGGCAG
TCTTAAACGCCTTGGTACCGATCATGTTGACAGCTTGCTATTGCATCGACCTGACCCGCTCATGGAACCAGAAGATGTTG
CTGAAGCCTTTCTGCAATTGCAAAATGAAGGTAAAGTTCGGCAGTTCGGGGTTTCCAACTTCAATCCTGCTCAGATTGAA
CTGCTCCAACAGGCGGTGCCGCAACGATTGATCATCAATCAATTGCAGTTTTCCCTGATGCACACAGGCATGATTGATGC
CGGCATGCATACAAACATGGCAGATGCCCGTTCCATTGATCATGATGGCGGTCTTCTCCCATACAGTCAGCAGCATCATA
TGGCAATTCAGGCGTGGAGTCCTTTCCAATATGGCTTCTTTGAAGGTGTCTTCATCGACAACGATAAATTCCCTGAATTA
AATGCCTTACTTCAAAAGCTGGCCGATCAATATACCACCAATCCCAACGCAATTGCTGCTGCCTGGCTCTTGCGTGTACC
AGCTGATGTGCAAGTCATCGCCGGAACCACCAAACCCGCTCGCATTCGCGCCATCGCCGAAGCCGGCGACATTGCTTTGA
CCCGGCAAGAATGGTATGACCTCTACTTCGCCTTCGCCGCCGGAAACGACCTGCCATAA

Upstream 100 bases:

>100_bases
CTCAAATTAGCTCGTCCTTGAGGGTGCTTTCTCACGCAATCATCACTGCTTTTGTGATAATCTTAAAGCATCATGGAACA
ATTCTGAAAGGATGCTCATT

Downstream 100 bases:

>100_bases
TCAGACAGAGCGTTCAATGGCGCGGTTAGAAACCGACGCATAAGCGGCCTCAAGTGCATTGACCGGGCTTTGGTCAGTCT
GCTTGAGGTCCTTACACGCA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKMIDLGRSGLHASAIALGVMRLPNLDRPRATELLDAAYDVGINFFDNADVYSNGKAEQLFGDALKKASFTRDQVLIQTK
VGIVNDRKATHRYDFSKEHIVDAVNGSLKRLGTDHVDSLLLHRPDPLMEPEDVAEAFLQLQNEGKVRQFGVSNFNPAQIE
LLQQAVPQRLIINQLQFSLMHTGMIDAGMHTNMADARSIDHDGGLLPYSQQHHMAIQAWSPFQYGFFEGVFIDNDKFPEL
NALLQKLADQYTTNPNAIAAAWLLRVPADVQVIAGTTKPARIRAIAEAGDIALTRQEWYDLYFAFAAGNDLP

Sequences:

>Translated_312_residues
MKMIDLGRSGLHASAIALGVMRLPNLDRPRATELLDAAYDVGINFFDNADVYSNGKAEQLFGDALKKASFTRDQVLIQTK
VGIVNDRKATHRYDFSKEHIVDAVNGSLKRLGTDHVDSLLLHRPDPLMEPEDVAEAFLQLQNEGKVRQFGVSNFNPAQIE
LLQQAVPQRLIINQLQFSLMHTGMIDAGMHTNMADARSIDHDGGLLPYSQQHHMAIQAWSPFQYGFFEGVFIDNDKFPEL
NALLQKLADQYTTNPNAIAAAWLLRVPADVQVIAGTTKPARIRAIAEAGDIALTRQEWYDLYFAFAAGNDLP
>Mature_312_residues
MKMIDLGRSGLHASAIALGVMRLPNLDRPRATELLDAAYDVGINFFDNADVYSNGKAEQLFGDALKKASFTRDQVLIQTK
VGIVNDRKATHRYDFSKEHIVDAVNGSLKRLGTDHVDSLLLHRPDPLMEPEDVAEAFLQLQNEGKVRQFGVSNFNPAQIE
LLQQAVPQRLIINQLQFSLMHTGMIDAGMHTNMADARSIDHDGGLLPYSQQHHMAIQAWSPFQYGFFEGVFIDNDKFPEL
NALLQKLADQYTTNPNAIAAAWLLRVPADVQVIAGTTKPARIRAIAEAGDIALTRQEWYDLYFAFAAGNDLP

Specific function: Unknown

COG id: COG4989

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=293, Percent_Identity=30.0341296928328, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI4504825, Length=293, Percent_Identity=30.0341296928328, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI27436964, Length=310, Percent_Identity=26.1290322580645, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI27436966, Length=297, Percent_Identity=27.2727272727273, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI27436962, Length=301, Percent_Identity=27.2425249169435, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI27436971, Length=161, Percent_Identity=34.7826086956522, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI48994888, Length=318, Percent_Identity=33.6477987421384, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1788070, Length=323, Percent_Identity=28.7925696594427, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI87081735, Length=332, Percent_Identity=25.3012048192771, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788081, Length=239, Percent_Identity=29.2887029288703, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789375, Length=324, Percent_Identity=25.9259259259259, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082198, Length=283, Percent_Identity=26.8551236749117, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786400, Length=147, Percent_Identity=29.2517006802721, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787674, Length=282, Percent_Identity=26.5957446808511, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=344, Percent_Identity=24.1279069767442, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=301, Percent_Identity=24.2524916943522, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323998, Length=301, Percent_Identity=23.9202657807309, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319951, Length=213, Percent_Identity=25.3521126760563, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640980, Length=165, Percent_Identity=29.6969696969697, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45549126, Length=165, Percent_Identity=29.6969696969697, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646159, Length=287, Percent_Identity=26.8292682926829, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34715; Mature: 34715

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00136 SUBTILASE_ASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMIDLGRSGLHASAIALGVMRLPNLDRPRATELLDAAYDVGINFFDNADVYSNGKAEQL
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCHHHH
FGDALKKASFTRDQVLIQTKVGIVNDRKATHRYDFSKEHIVDAVNGSLKRLGTDHVDSLL
HHHHHHHHCCCHHHEEEEEECCEECCCCCHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
LHRPDPLMEPEDVAEAFLQLQNEGKVRQFGVSNFNPAQIELLQQAVPQRLIINQLQFSLM
HCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HTGMIDAGMHTNMADARSIDHDGGLLPYSQQHHMAIQAWSPFQYGFFEGVFIDNDKFPEL
HCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCHH
NALLQKLADQYTTNPNAIAAAWLLRVPADVQVIAGTTKPARIRAIAEAGDIALTRQEWYD
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCHHEEEECCCCCEEEEHHHHHE
LYFAFAAGNDLP
EEEEEECCCCCC
>Mature Secondary Structure
MKMIDLGRSGLHASAIALGVMRLPNLDRPRATELLDAAYDVGINFFDNADVYSNGKAEQL
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCHHHH
FGDALKKASFTRDQVLIQTKVGIVNDRKATHRYDFSKEHIVDAVNGSLKRLGTDHVDSLL
HHHHHHHHCCCHHHEEEEEECCEECCCCCHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
LHRPDPLMEPEDVAEAFLQLQNEGKVRQFGVSNFNPAQIELLQQAVPQRLIINQLQFSLM
HCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HTGMIDAGMHTNMADARSIDHDGGLLPYSQQHHMAIQAWSPFQYGFFEGVFIDNDKFPEL
HCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCHH
NALLQKLADQYTTNPNAIAAAWLLRVPADVQVIAGTTKPARIRAIAEAGDIALTRQEWYD
HHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCHHEEEECCCCCEEEEHHHHHE
LYFAFAAGNDLP
EEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]