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The map label for this gene is hit [H]

Identifier: 116495201

GI number: 116495201

Start: 1715014

End: 1715442

Strand: Direct

Name: hit [H]

Synonym: LSEI_1720

Alternate gene names: 116495201

Gene position: 1715014-1715442 (Clockwise)

Preceding gene: 116495196

Following gene: 116495202

Centisome position: 59.24

GC content: 43.59

Gene sequence:

>429_bases
ATGAATGATTGCATTTTTTGCAAAATTGTCCGTAACGAAATCCCCAATGTTACCGTATATGAAGATGACGTTGTCAAAGC
CTTTCTGGATATCACGCAGGTTACACCGGGACATACTTTATTAGTCCCCAAAGTTCACATTCCAGATATTTTCGCTTATG
ACACTGAACTTGCCGCAGCGGTTTTTGAACGTCTGCCAAAAATTGCCCGCGCCATCAAGGCCAGTGACCCGGCAATTAAA
GGTATGAATATTTTGAATAACAACGGCAAGGTCGCCTATCAAAGCGTTTTTCACTCACATATCCATTTGATTCCTCGCTA
TAGCGATCAAGATGATTTTGGCATGCACTTTGGCGATCACAGTGCACAGTATGACACAGAGAAACTTGAAGCGGTCGCTG
ACAAAATTCGTACCCAGCTGGAGGCCTAA

Upstream 100 bases:

>100_bases
TCATCTTACCAGTCCCAATCTGTATAATTTCAGTTAGTGATATGATAGCATGAAATCAAGGTTTCTATTTAAAAAGCGCA
AGCAGAAATGAGGCAGCAAC

Downstream 100 bases:

>100_bases
GCATGAAATTTAAACACGGCTTTTTACTCGGAGCACTGACCGGAACAGTTTATGCGCTGTTGACTGCAAAAAAAACCGGT
CCACAACTTCAACAAGAGAT

Product: diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MNDCIFCKIVRNEIPNVTVYEDDVVKAFLDITQVTPGHTLLVPKVHIPDIFAYDTELAAAVFERLPKIARAIKASDPAIK
GMNILNNNGKVAYQSVFHSHIHLIPRYSDQDDFGMHFGDHSAQYDTEKLEAVADKIRTQLEA

Sequences:

>Translated_142_residues
MNDCIFCKIVRNEIPNVTVYEDDVVKAFLDITQVTPGHTLLVPKVHIPDIFAYDTELAAAVFERLPKIARAIKASDPAIK
GMNILNNNGKVAYQSVFHSHIHLIPRYSDQDDFGMHFGDHSAQYDTEKLEAVADKIRTQLEA
>Mature_142_residues
MNDCIFCKIVRNEIPNVTVYEDDVVKAFLDITQVTPGHTLLVPKVHIPDIFAYDTELAAAVFERLPKIARAIKASDPAIK
GMNILNNNGKVAYQSVFHSHIHLIPRYSDQDDFGMHFGDHSAQYDTEKLEAVADKIRTQLEA

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=103, Percent_Identity=34.9514563106796, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17506713, Length=103, Percent_Identity=36.8932038834951, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320078, Length=145, Percent_Identity=37.2413793103448, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15980; Mature: 15980

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDCIFCKIVRNEIPNVTVYEDDVVKAFLDITQVTPGHTLLVPKVHIPDIFAYDTELAAA
CCCCEEEEEEHHHCCCCEEEHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEHHHHHHHHH
VFERLPKIARAIKASDPAIKGMNILNNNGKVAYQSVFHSHIHLIPRYSDQDDFGMHFGDH
HHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SAQYDTEKLEAVADKIRTQLEA
CCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNDCIFCKIVRNEIPNVTVYEDDVVKAFLDITQVTPGHTLLVPKVHIPDIFAYDTELAAA
CCCCEEEEEEHHHCCCCEEEHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEHHHHHHHHH
VFERLPKIARAIKASDPAIKGMNILNNNGKVAYQSVFHSHIHLIPRYSDQDDFGMHFGDH
HHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SAQYDTEKLEAVADKIRTQLEA
CCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]