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The map label for this gene is ctpA [H]

Identifier: 116494881

GI number: 116494881

Start: 1382375

End: 1383760

Strand: Direct

Name: ctpA [H]

Synonym: LSEI_1395

Alternate gene names: 116494881

Gene position: 1382375-1383760 (Clockwise)

Preceding gene: 116494880

Following gene: 116494882

Centisome position: 47.75

GC content: 48.77

Gene sequence:

>1386_bases
TTGATAATTGTCATCGTCGCACTTGGCGGTGGTGTCGCAGGCGGTTACGCGCTCTCTTATCAGCAAGCTCAACAAAGTGT
TTTGAAAACAAGTGTCCCCAAGGAACTAGCACCCGTTATTGCTGCTTATGAGACAGTTACCAATAACTACTATAAAAGCG
TCAATACGACCAAATTAACCGATGGCGCGATTAAAGGTATGCTGGCAACGTTAGATGATCCATATTCCGTTTACTTGCAG
AATAACGATAAAACCAATCTTGATGACACGATTTCGGCTTCATTTGGCGGTATCGGTGCCACCATCCAGCAAAATCATGA
CAGTCTTTCCATCGCCAGCATTTTACCTGATACGCCCGCCAAAAAAGCAGGCATGCAAGTCGGCGATGTGCTGCTCAAGG
TCAACGGTAAAGATGTCTCCAAGCAAACCGTTAGCAAGGCAGTTGCCAAAATTCGCGGTAAAATCGGTACCACAGTGGCC
GTCACCGTTAAGCGCGGCAGCAAACAAGCGACCTTCTCGATGAAGCGGCAGAAAATCACGGTTGACACTGTCACTGGCCA
ACTTGCTTCGGCCAACAAACAGGTCGGCGTCATTACTATCTCGACTTTTAGCGAACCAACCGTCAAACAATTCAAGGCCA
CTGTTAAGAAATTACGCAAAGAAGGGGCCAAATCCTTTGTCCTCGACTTACGGCAAAATCCAGGCGGCATGATGAGTGCG
GCTTTGTCCATCAGCTCCATGTTCTCTAAAAACGGCCAAACTGTTCTGCAAGTCGAAGACCGCAACGGTGCCAAGGAAGT
CTATAAGGCTGGCAAGAAACTCGATGACGGCTTTAAAGTCACTGAAAAAACGGCGGTCTTAATTGATGGTAATTCGGCCT
CAGCCAGTGAAATCACCGCTGCAGCACTTCACCAAAACAGCAACATTCCGCTTGTCGGTGAAAAGAGTTTCGGCAAAGGC
ACTGTCCAAAATGTCGGCGAAATGGGCAGCAACAAAGAACTCAAGCTGACCATCGCTAAATGGTTAACGCCAAATGGCAC
TTGGATTAACCACAAAGGTCTAACACCCGATATCAAGGTCGACTACCCAGCCGCGGCGAAGATCACCTTGATCAACGCCA
CTCAGCTCAAACCAGGCGATAAAGGCAGCGATGTGAAGTCCTTGCAACAAATGCTCACGGCACTTAAAGTCGGCTCCGTC
ACTGTCAATAGTCAATACGACGATGCCACCCAAGCCGCTGTCAAAACGTTCCAGCAAGCAAATAAGCTTGACGCAACAGG
AACAGCGGATCAGGATACGTTGGCAACGCTCGCACAGAAGTTGAGTGCACAGTTGACCAAGGATGATCCGATGATGAAGG
CGGCTGTGGATGCAGTAGCCAAGTGA

Upstream 100 bases:

>100_bases
AGCATGGCCGTTTTTGACGAAACGTATCGCGCCTATGAGGCGAGTGAAAGCACAGGAGGCGATTCGTATCAATAAACGTA
GATTACCGTGGTGGGCCGTT

Downstream 100 bases:

>100_bases
AAATCAAATAGGTTATGATATGCGCGTATATGCCTTTTAGGAGGTGTGTACGCGTTTTTTTCGCACGTTCAATGATCCGC
ATTTTCGTGTTGTCATGGTT

Product: periplasmic protease

Products: NA

Alternate protein names: C-terminal processing protease [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MIIVIVALGGGVAGGYALSYQQAQQSVLKTSVPKELAPVIAAYETVTNNYYKSVNTTKLTDGAIKGMLATLDDPYSVYLQ
NNDKTNLDDTISASFGGIGATIQQNHDSLSIASILPDTPAKKAGMQVGDVLLKVNGKDVSKQTVSKAVAKIRGKIGTTVA
VTVKRGSKQATFSMKRQKITVDTVTGQLASANKQVGVITISTFSEPTVKQFKATVKKLRKEGAKSFVLDLRQNPGGMMSA
ALSISSMFSKNGQTVLQVEDRNGAKEVYKAGKKLDDGFKVTEKTAVLIDGNSASASEITAAALHQNSNIPLVGEKSFGKG
TVQNVGEMGSNKELKLTIAKWLTPNGTWINHKGLTPDIKVDYPAAAKITLINATQLKPGDKGSDVKSLQQMLTALKVGSV
TVNSQYDDATQAAVKTFQQANKLDATGTADQDTLATLAQKLSAQLTKDDPMMKAAVDAVAK

Sequences:

>Translated_461_residues
MIIVIVALGGGVAGGYALSYQQAQQSVLKTSVPKELAPVIAAYETVTNNYYKSVNTTKLTDGAIKGMLATLDDPYSVYLQ
NNDKTNLDDTISASFGGIGATIQQNHDSLSIASILPDTPAKKAGMQVGDVLLKVNGKDVSKQTVSKAVAKIRGKIGTTVA
VTVKRGSKQATFSMKRQKITVDTVTGQLASANKQVGVITISTFSEPTVKQFKATVKKLRKEGAKSFVLDLRQNPGGMMSA
ALSISSMFSKNGQTVLQVEDRNGAKEVYKAGKKLDDGFKVTEKTAVLIDGNSASASEITAAALHQNSNIPLVGEKSFGKG
TVQNVGEMGSNKELKLTIAKWLTPNGTWINHKGLTPDIKVDYPAAAKITLINATQLKPGDKGSDVKSLQQMLTALKVGSV
TVNSQYDDATQAAVKTFQQANKLDATGTADQDTLATLAQKLSAQLTKDDPMMKAAVDAVAK
>Mature_461_residues
MIIVIVALGGGVAGGYALSYQQAQQSVLKTSVPKELAPVIAAYETVTNNYYKSVNTTKLTDGAIKGMLATLDDPYSVYLQ
NNDKTNLDDTISASFGGIGATIQQNHDSLSIASILPDTPAKKAGMQVGDVLLKVNGKDVSKQTVSKAVAKIRGKIGTTVA
VTVKRGSKQATFSMKRQKITVDTVTGQLASANKQVGVITISTFSEPTVKQFKATVKKLRKEGAKSFVLDLRQNPGGMMSA
ALSISSMFSKNGQTVLQVEDRNGAKEVYKAGKKLDDGFKVTEKTAVLIDGNSASASEITAAALHQNSNIPLVGEKSFGKG
TVQNVGEMGSNKELKLTIAKWLTPNGTWINHKGLTPDIKVDYPAAAKITLINATQLKPGDKGSDVKSLQQMLTALKVGSV
TVNSQYDDATQAAVKTFQQANKLDATGTADQDTLATLAQKLSAQLTKDDPMMKAAVDAVAK

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Associated With The Periplasmic Protein Side Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=312, Percent_Identity=32.3717948717949, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 48690; Mature: 48690

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVIVALGGGVAGGYALSYQQAQQSVLKTSVPKELAPVIAAYETVTNNYYKSVNTTKLT
CEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEC
DGAIKGMLATLDDPYSVYLQNNDKTNLDDTISASFGGIGATIQQNHDSLSIASILPDTPA
CHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHCCCCCCCCEEECCCCCEEEEHHCCCCCH
KKAGMQVGDVLLKVNGKDVSKQTVSKAVAKIRGKIGTTVAVTVKRGSKQATFSMKRQKIT
HHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEHHHCEEE
VDTVTGQLASANKQVGVITISTFSEPTVKQFKATVKKLRKEGAKSFVLDLRQNPGGMMSA
EEECCCHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEHEECCCCCHHHHH
ALSISSMFSKNGQTVLQVEDRNGAKEVYKAGKKLDDGFKVTEKTAVLIDGNSASASEITA
HHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCCCCCCEEECCEEEEEECCCCCHHHHHH
AALHQNSNIPLVGEKSFGKGTVQNVGEMGSNKELKLTIAKWLTPNGTWINHKGLTPDIKV
HHHHCCCCCCEEECCCCCCCHHHHHHHCCCCCEEEEEEEEEECCCCCEEECCCCCCCEEE
DYPAAAKITLINATQLKPGDKGSDVKSLQQMLTALKVGSVTVNSQYDDATQAAVKTFQQA
CCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHH
NKLDATGTADQDTLATLAQKLSAQLTKDDPMMKAAVDAVAK
HCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIIVIVALGGGVAGGYALSYQQAQQSVLKTSVPKELAPVIAAYETVTNNYYKSVNTTKLT
CEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEC
DGAIKGMLATLDDPYSVYLQNNDKTNLDDTISASFGGIGATIQQNHDSLSIASILPDTPA
CHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHCCCCCCCCEEECCCCCEEEEHHCCCCCH
KKAGMQVGDVLLKVNGKDVSKQTVSKAVAKIRGKIGTTVAVTVKRGSKQATFSMKRQKIT
HHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEHHHCEEE
VDTVTGQLASANKQVGVITISTFSEPTVKQFKATVKKLRKEGAKSFVLDLRQNPGGMMSA
EEECCCHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEHEECCCCCHHHHH
ALSISSMFSKNGQTVLQVEDRNGAKEVYKAGKKLDDGFKVTEKTAVLIDGNSASASEITA
HHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCCCCCCEEECCEEEEEECCCCCHHHHHH
AALHQNSNIPLVGEKSFGKGTVQNVGEMGSNKELKLTIAKWLTPNGTWINHKGLTPDIKV
HHHHCCCCCCEEECCCCCCCHHHHHHHCCCCCEEEEEEEEEECCCCCEEECCCCCCCEEE
DYPAAAKITLINATQLKPGDKGSDVKSLQQMLTALKVGSVTVNSQYDDATQAAVKTFQQA
CCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHH
NKLDATGTADQDTLATLAQKLSAQLTKDDPMMKAAVDAVAK
HCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8996100; 9734814; 9384377 [H]