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The map label for this gene is xerD [H]

Identifier: 116494854

GI number: 116494854

Start: 1358002

End: 1358883

Strand: Direct

Name: xerD [H]

Synonym: LSEI_1368

Alternate gene names: 116494854

Gene position: 1358002-1358883 (Clockwise)

Preceding gene: 116494853

Following gene: 116494855

Centisome position: 46.9

GC content: 46.49

Gene sequence:

>882_bases
ATGCATGGGTTGATCGCGGATTTTATTCATTATCTAAATGTTGAACGCGGATTGGCAAAAGCCACCCAAACTAGCTATCA
GCAGGATTTGATCACTTTTTCGGCTTGGCTAGCGGCCCGAAAAAGAAGGACATTTCCTGAGGAGTTCGGTACCATCCAGT
CCTTTTTAAAGGAGCAGAATGCCACCAAGGCGCCTGCTTCAGTTAGCCGCATGATTTCTGCTTTACGCAAGTTTTATCGG
TTTTTACTGCGTGAAGGGGCAATTTCAGCTGATCCAATGACCAAGATTGACACCCCAAAACGTGCCCAACATTTACCAGC
AACGTTGTCGAGTCAAGAAGTCGATGCTTTGATGGCCAAACCAGATACCGACAAGCCATTGGGATTACGTGATCGCGCTA
TTTTTGAGTTGATGTATGCCACTGGGTTACGGGTTTCAGAAGTTGTTGATTTACGTCTTGATCAATTGCATTTGGCAATG
AATCTACTTCAAGTGACTGGTAAAGGGGACAAAGAACGACTGGTTCCCATTAGTCCGCAAGCCACACAATGGGTGGATCG
CTATCTGCAAGAGGCCAGACCCAAATTACTCAAACGAGTACAACCTAAAAACGTTTTTGTCAATTTTCACGGTGGGCCAA
TGACTCGCCAAGGGATCTGGAAGAACCTCAAAGCATATATTGCAAGTATCGGCATTGAAAAAGATGTCACACCGCATACT
CTTCGTCACAGCTTTGCGACAAGGTTGCTCGAAAACGGTGCTGACCTGCGCGTGGTTCAAGAACTACTCGGCCACAGCGA
CATCAGCACGACCCAGATTTACACCCATTTAAGCAATCAACATCTAGTTGCGGTCTATCATAAAACGCATCCGCGCGGGT
AG

Upstream 100 bases:

>100_bases
AAGCGCGCACTGGGCCATTTGTTGAAGGCTGGCTTAGTGAAAGAGGAAGCTGGGTATACGATTTTGACGGCCGCAGCTAA
GGCGTCTCGGGAGTAACATC

Downstream 100 bases:

>100_bases
CTATTTTGACAGGGTGTTCCTTTCTAAGAATATGTTTGATGACTAAGAGATTGTGGCCATCAGCATTGCCATGGGCAGTC
TAGCTCGAATACTAAGATAG

Product: integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MHGLIADFIHYLNVERGLAKATQTSYQQDLITFSAWLAARKRRTFPEEFGTIQSFLKEQNATKAPASVSRMISALRKFYR
FLLREGAISADPMTKIDTPKRAQHLPATLSSQEVDALMAKPDTDKPLGLRDRAIFELMYATGLRVSEVVDLRLDQLHLAM
NLLQVTGKGDKERLVPISPQATQWVDRYLQEARPKLLKRVQPKNVFVNFHGGPMTRQGIWKNLKAYIASIGIEKDVTPHT
LRHSFATRLLENGADLRVVQELLGHSDISTTQIYTHLSNQHLVAVYHKTHPRG

Sequences:

>Translated_293_residues
MHGLIADFIHYLNVERGLAKATQTSYQQDLITFSAWLAARKRRTFPEEFGTIQSFLKEQNATKAPASVSRMISALRKFYR
FLLREGAISADPMTKIDTPKRAQHLPATLSSQEVDALMAKPDTDKPLGLRDRAIFELMYATGLRVSEVVDLRLDQLHLAM
NLLQVTGKGDKERLVPISPQATQWVDRYLQEARPKLLKRVQPKNVFVNFHGGPMTRQGIWKNLKAYIASIGIEKDVTPHT
LRHSFATRLLENGADLRVVQELLGHSDISTTQIYTHLSNQHLVAVYHKTHPRG
>Mature_293_residues
MHGLIADFIHYLNVERGLAKATQTSYQQDLITFSAWLAARKRRTFPEEFGTIQSFLKEQNATKAPASVSRMISALRKFYR
FLLREGAISADPMTKIDTPKRAQHLPATLSSQEVDALMAKPDTDKPLGLRDRAIFELMYATGLRVSEVVDLRLDQLHLAM
NLLQVTGKGDKERLVPISPQATQWVDRYLQEARPKLLKRVQPKNVFVNFHGGPMTRQGIWKNLKAYIASIGIEKDVTPHT
LRHSFATRLLENGADLRVVQELLGHSDISTTQIYTHLSNQHLVAVYHKTHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=42.1232876712329, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1790244, Length=295, Percent_Identity=34.9152542372881, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1790768, Length=168, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790767, Length=187, Percent_Identity=26.2032085561497, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33228; Mature: 33228

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGLIADFIHYLNVERGLAKATQTSYQQDLITFSAWLAARKRRTFPEEFGTIQSFLKEQN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
ATKAPASVSRMISALRKFYRFLLREGAISADPMTKIDTPKRAQHLPATLSSQEVDALMAK
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHCC
PDTDKPLGLRDRAIFELMYATGLRVSEVVDLRLDQLHLAMNLLQVTGKGDKERLVPISPQ
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCH
ATQWVDRYLQEARPKLLKRVQPKNVFVNFHGGPMTRQGIWKNLKAYIASIGIEKDVTPHT
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
LRHSFATRLLENGADLRVVQELLGHSDISTTQIYTHLSNQHLVAVYHKTHPRG
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MHGLIADFIHYLNVERGLAKATQTSYQQDLITFSAWLAARKRRTFPEEFGTIQSFLKEQN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
ATKAPASVSRMISALRKFYRFLLREGAISADPMTKIDTPKRAQHLPATLSSQEVDALMAK
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHCC
PDTDKPLGLRDRAIFELMYATGLRVSEVVDLRLDQLHLAMNLLQVTGKGDKERLVPISPQ
CCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCH
ATQWVDRYLQEARPKLLKRVQPKNVFVNFHGGPMTRQGIWKNLKAYIASIGIEKDVTPHT
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHH
LRHSFATRLLENGADLRVVQELLGHSDISTTQIYTHLSNQHLVAVYHKTHPRG
HHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA