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The map label for this gene is coaD

Identifier: 116494807

GI number: 116494807

Start: 1304057

End: 1304560

Strand: Direct

Name: coaD

Synonym: LSEI_1318

Alternate gene names: 116494807

Gene position: 1304057-1304560 (Clockwise)

Preceding gene: 116494806

Following gene: 116494808

Centisome position: 45.04

GC content: 46.83

Gene sequence:

>504_bases
ATGACTAAAAAAATTGCAGTGTTTCCCGGTAGTTTTGATCCTTTCACGAACGGTCATCTTGATACCGTCAAAAGAGCTAG
TCGGTTGTTTGATGAAGTGGTTGTAGCAGCCATGACCAACACGAGCAAAAAGCCGCTTTTTTCCAGTGAAGAGAAATTGG
CGCTGATCAGTGAAAGCACCGCTGGGCTACCAAATGTTAAAGCCATGGCAGCGCCTAAACGATTAACAGTTGAATTTGCC
CGGTCAATCGGTGCCCAGTTTATGATTCGTGGTATCCGCAATGTCGCGGACTTTGGTTACGAGGCTGATATTGCGACGGT
GAATCATGATCTCGATCCTGAAATCGAAACAGTTTTCTTGCTGGCAGACAAGCAATATGATGCCTTATCCAGTACCATCA
TCAAAGAGGTCGCGGCCTTTGGCGGTGACGTTCATCGTTTTGTGCCTGCGCCTGTCGAAGCAGCTTTGTATGCGAAACTA
GGTGACGCTCATCAAACCAAGTAA

Upstream 100 bases:

>100_bases
GATGTGACTTATCCTGATGAGATCCCCGGCTACATCAAGCTACGGCGCCAAACCTATGGGGTGGCGCAGGTCTTAATTTT
AGAGCGAAGCGAGGAAAACA

Downstream 100 bases:

>100_bases
TCAGAAACGTCGGCGCTGGCGTTGGCTTATCGGACTGTTAATAGCAGTCGTTTTGTTGGCTGTCTTCTTTTTGATCCCAA
CCAATTACTATCTAGAAGCG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MTKKIAVFPGSFDPFTNGHLDTVKRASRLFDEVVVAAMTNTSKKPLFSSEEKLALISESTAGLPNVKAMAAPKRLTVEFA
RSIGAQFMIRGIRNVADFGYEADIATVNHDLDPEIETVFLLADKQYDALSSTIIKEVAAFGGDVHRFVPAPVEAALYAKL
GDAHQTK

Sequences:

>Translated_167_residues
MTKKIAVFPGSFDPFTNGHLDTVKRASRLFDEVVVAAMTNTSKKPLFSSEEKLALISESTAGLPNVKAMAAPKRLTVEFA
RSIGAQFMIRGIRNVADFGYEADIATVNHDLDPEIETVFLLADKQYDALSSTIIKEVAAFGGDVHRFVPAPVEAALYAKL
GDAHQTK
>Mature_166_residues
TKKIAVFPGSFDPFTNGHLDTVKRASRLFDEVVVAAMTNTSKKPLFSSEEKLALISESTAGLPNVKAMAAPKRLTVEFAR
SIGAQFMIRGIRNVADFGYEADIATVNHDLDPEIETVFLLADKQYDALSSTIIKEVAAFGGDVHRFVPAPVEAALYAKLG
DAHQTK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=47.1698113207547, Blast_Score=153, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_LACC3 (Q039M3)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_806541.1
- ProteinModelPortal:   Q039M3
- SMR:   Q039M3
- STRING:   Q039M3
- GeneID:   4419679
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_1318
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q039M3
- ProtClustDB:   PRK00168
- BioCyc:   LCAS321967:LSEI_1318-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18129; Mature: 17998

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKIAVFPGSFDPFTNGHLDTVKRASRLFDEVVVAAMTNTSKKPLFSSEEKLALISEST
CCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCC
AGLPNVKAMAAPKRLTVEFARSIGAQFMIRGIRNVADFGYEADIATVNHDLDPEIETVFL
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEE
LADKQYDALSSTIIKEVAAFGGDVHRFVPAPVEAALYAKLGDAHQTK
EECCCHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TKKIAVFPGSFDPFTNGHLDTVKRASRLFDEVVVAAMTNTSKKPLFSSEEKLALISEST
CCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCC
AGLPNVKAMAAPKRLTVEFARSIGAQFMIRGIRNVADFGYEADIATVNHDLDPEIETVFL
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEE
LADKQYDALSSTIIKEVAAFGGDVHRFVPAPVEAALYAKLGDAHQTK
EECCCHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA