| Definition | Lactobacillus casei ATCC 334, complete genome. |
|---|---|
| Accession | NC_008526 |
| Length | 2,895,264 |
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The map label for this gene is uvrA [H]
Identifier: 116494782
GI number: 116494782
Start: 1269562
End: 1271844
Strand: Direct
Name: uvrA [H]
Synonym: LSEI_1291
Alternate gene names: 116494782
Gene position: 1269562-1271844 (Clockwise)
Preceding gene: 116494781
Following gene: 116494783
Centisome position: 43.85
GC content: 46.91
Gene sequence:
>2283_bases ATGTTTGACCACGGCTTCATTGAGGTCCACGATGCTAACCAAAATAACTTGCAACACGTCAACGTAAAGATTCCTAAGGA TGCGATTAGTGTTTTCGTCGGCCGATCAGGTTCAGGTAAGTCTTCTTTAGTTTTTGATACCATTGCCGCTGAGTCCCGCC GCGAACTGAATGAGACTTTTCCGAGCTTTACCCAACAGTATCTACCTAAATATGGTCAGCCGGATGTCGGCCAAATCGAC CATTTACCAGTGGCAATTGTTGTCGAGCAGAAGCGCATTGGTAAAAATGCGCGGTCAACGCTTGCCACCTATACGGGTAT TTATTCCTTGTTGCGGTTGTTGTTTTCACGAGCTGGCAAGCCGTTTATTGGCTATTCGGACACTTTTTCTTTTAACCTGC CACAGGGAATGTGCAAGACATGTCAGGGACTCGGGTATGTGGATGACATTGATGTTAAAAAGTTAATTGACCCGAACAAA TCGTTGAATCAGGGCGCGATTACGTTTGTCAGTTTTGGACCAGACACGTGGCGGTGGAAACGCTACGCTTACAGTGGTTT ATTTGATAATGACAAACGATTGGGCGACTATACAAAGCAGGAAATGGACACCTTATTGTATGCCCCGCAGCAAACACTAG ATCATGCGCCAACAAAGTGGCCTAAAACAGCTTTGTACGAAGGCGTTGTGCCGCGAATCAGGCGGTCCATTATTGGTAAG AAAGAGGCTGAACATCATAAGACGGCGTTGGCAGAAATTGTCACTCGTATGCCATGTCCAACCTGCCATGGAACACGTTT GCGGCCAGAGGTTCTGACTTGTCTCATCAATCAAACGAATATTGCTCAAGTGCTGCAAATGGATCTCGTCAAGGTTCGCC ATTTTCTGAATGGCATTCAAGAACCACTTGTTCAGGACGTGATCCGTGAGCTGTTACGAAAAATCGATTCTTTGATTGAC ATTGGGTTAGGCTACCTATCCCTTGATCGACCGACTGAGACATTGTCGGGCGGCGAAACCCAGCGCATTAAAATTGCCAA GTTTTTGACTAGTGCCTTAGTCGATATGGTTTACATTTTGGATGAGCCCAGTGTTGGCTTGCATCCGCATGATATTGAAT TAATCAAGCGTGCCATTTTGCGTTTGAAGGAGAAAGGCAACACTATTTTAATCGTTGAACACAATCCGGCACTGATTGCG ATTGGCGATAATATTGTCGAAGTGGGTCCCGGAGCGGGGACAACGGGCGGGCATATCACCTTTACAGGTACCTACCAAGC CCTTTTAGACAGTGACACTTTGACAGGGAAACTGTTGAAACAGCCATTGACTTTTCGCCAGCCGCGGCCAGCCACATCAA CGATTTCATTGCAGCATATTCATCGACATAATTTAAAAGATGTTAGTGTCGCAGTACCGCTGGGCATTGAAACTGTGATT TCCGGGGTCGCTGGTTCCGGGAAGAGTACGTTGGTATCTGCTTTACGTGATCAGTTAACCGCACCATATATTGATTTGGC ACAAGCCGATATCGGTGCTAATATCCGCTCAGCGCCTGCCACATATCTCTCAATCCTCGATCCAATTCGCAAAGTCTTTG CTGACGCGAATCATGTGGCTAGCAGTTGGTTTAGTTACAACGGTCGCGGCGCTTGCCCACGTTGTAAGGGTAAAGGCGTG ACCATTACCAATATGGCGTTCATGGATCCGGTTGTACAGACTTGTGAACAATGTCATGGACGACGTTACAATGATCAGGC CCTGAGCTACACTTATCATGATAAAAATATCTCTGACGTGCTGCGCATGCCGATTACAAAAGCACAAAACTTTTTTACGG ATGTACCAGCTATTGCCGCACCATTGCGAAATATGGCACGGGTTGGCCTCGACTATCTAACACTTGGGCAACCATTGACC ACACTTTCCGGTGGCGAAAAGCAGCGTTTAAAGTTGGCTGTCGAATTGAACCGCACCGGTACCTTGTACTTGCTTGATGA GCCAACCGCTGGCCTACATTTGCAAGATGTGAAAAAGTTGATCCAGCTATTTGACGAACTTGTCGCAGATGGCAACTCGT TGATCATCGTTGAACACAACTTAGAGGTCATTAGTCAGGCAGACTGGCTCATTGACATGGGTCCAGACGCTGGCATCTAT GGTGGTCAAGTCCGCTATACGGGGACACCTGAAAATAGCATGACTGTCAAACAATCACGAACGGGCCAAGCCATGAAACA ATACAATCAGGCGCCGGAACGGCAACAAAATAATAGGCATTGA
Upstream 100 bases:
>100_bases ACAGTAAAAATGTCAATCTGTAGCAAATTGGTTTTTATGATTATCAGAAACGCTAAAGTGATAAGCTGAAATTAACGAAG AGAAGAAATGGAGGGATAAT
Downstream 100 bases:
>100_bases CGCCAAACTTGATGTATTTGTATTGACCGTTCTGCGTCACGTTGCACTGAAACAAGAATGAGCTGGTGACTTGTTGTTTG CTTGGATCATCAGAGAAAAA
Product: excinuclease ATPase subunit
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 760; Mature: 760
Protein sequence:
>760_residues MFDHGFIEVHDANQNNLQHVNVKIPKDAISVFVGRSGSGKSSLVFDTIAAESRRELNETFPSFTQQYLPKYGQPDVGQID HLPVAIVVEQKRIGKNARSTLATYTGIYSLLRLLFSRAGKPFIGYSDTFSFNLPQGMCKTCQGLGYVDDIDVKKLIDPNK SLNQGAITFVSFGPDTWRWKRYAYSGLFDNDKRLGDYTKQEMDTLLYAPQQTLDHAPTKWPKTALYEGVVPRIRRSIIGK KEAEHHKTALAEIVTRMPCPTCHGTRLRPEVLTCLINQTNIAQVLQMDLVKVRHFLNGIQEPLVQDVIRELLRKIDSLID IGLGYLSLDRPTETLSGGETQRIKIAKFLTSALVDMVYILDEPSVGLHPHDIELIKRAILRLKEKGNTILIVEHNPALIA IGDNIVEVGPGAGTTGGHITFTGTYQALLDSDTLTGKLLKQPLTFRQPRPATSTISLQHIHRHNLKDVSVAVPLGIETVI SGVAGSGKSTLVSALRDQLTAPYIDLAQADIGANIRSAPATYLSILDPIRKVFADANHVASSWFSYNGRGACPRCKGKGV TITNMAFMDPVVQTCEQCHGRRYNDQALSYTYHDKNISDVLRMPITKAQNFFTDVPAIAAPLRNMARVGLDYLTLGQPLT TLSGGEKQRLKLAVELNRTGTLYLLDEPTAGLHLQDVKKLIQLFDELVADGNSLIIVEHNLEVISQADWLIDMGPDAGIY GGQVRYTGTPENSMTVKQSRTGQAMKQYNQAPERQQNNRH
Sequences:
>Translated_760_residues MFDHGFIEVHDANQNNLQHVNVKIPKDAISVFVGRSGSGKSSLVFDTIAAESRRELNETFPSFTQQYLPKYGQPDVGQID HLPVAIVVEQKRIGKNARSTLATYTGIYSLLRLLFSRAGKPFIGYSDTFSFNLPQGMCKTCQGLGYVDDIDVKKLIDPNK SLNQGAITFVSFGPDTWRWKRYAYSGLFDNDKRLGDYTKQEMDTLLYAPQQTLDHAPTKWPKTALYEGVVPRIRRSIIGK KEAEHHKTALAEIVTRMPCPTCHGTRLRPEVLTCLINQTNIAQVLQMDLVKVRHFLNGIQEPLVQDVIRELLRKIDSLID IGLGYLSLDRPTETLSGGETQRIKIAKFLTSALVDMVYILDEPSVGLHPHDIELIKRAILRLKEKGNTILIVEHNPALIA IGDNIVEVGPGAGTTGGHITFTGTYQALLDSDTLTGKLLKQPLTFRQPRPATSTISLQHIHRHNLKDVSVAVPLGIETVI SGVAGSGKSTLVSALRDQLTAPYIDLAQADIGANIRSAPATYLSILDPIRKVFADANHVASSWFSYNGRGACPRCKGKGV TITNMAFMDPVVQTCEQCHGRRYNDQALSYTYHDKNISDVLRMPITKAQNFFTDVPAIAAPLRNMARVGLDYLTLGQPLT TLSGGEKQRLKLAVELNRTGTLYLLDEPTAGLHLQDVKKLIQLFDELVADGNSLIIVEHNLEVISQADWLIDMGPDAGIY GGQVRYTGTPENSMTVKQSRTGQAMKQYNQAPERQQNNRH >Mature_760_residues MFDHGFIEVHDANQNNLQHVNVKIPKDAISVFVGRSGSGKSSLVFDTIAAESRRELNETFPSFTQQYLPKYGQPDVGQID HLPVAIVVEQKRIGKNARSTLATYTGIYSLLRLLFSRAGKPFIGYSDTFSFNLPQGMCKTCQGLGYVDDIDVKKLIDPNK SLNQGAITFVSFGPDTWRWKRYAYSGLFDNDKRLGDYTKQEMDTLLYAPQQTLDHAPTKWPKTALYEGVVPRIRRSIIGK KEAEHHKTALAEIVTRMPCPTCHGTRLRPEVLTCLINQTNIAQVLQMDLVKVRHFLNGIQEPLVQDVIRELLRKIDSLID IGLGYLSLDRPTETLSGGETQRIKIAKFLTSALVDMVYILDEPSVGLHPHDIELIKRAILRLKEKGNTILIVEHNPALIA IGDNIVEVGPGAGTTGGHITFTGTYQALLDSDTLTGKLLKQPLTFRQPRPATSTISLQHIHRHNLKDVSVAVPLGIETVI SGVAGSGKSTLVSALRDQLTAPYIDLAQADIGANIRSAPATYLSILDPIRKVFADANHVASSWFSYNGRGACPRCKGKGV TITNMAFMDPVVQTCEQCHGRRYNDQALSYTYHDKNISDVLRMPITKAQNFFTDVPAIAAPLRNMARVGLDYLTLGQPLT TLSGGEKQRLKLAVELNRTGTLYLLDEPTAGLHLQDVKKLIQLFDELVADGNSLIIVEHNLEVISQADWLIDMGPDAGIY GGQVRYTGTPENSMTVKQSRTGQAMKQYNQAPERQQNNRH
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=701, Percent_Identity=34.8074179743224, Blast_Score=394, Evalue=1e-110,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR003593 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 84227; Mature: 84227
Theoretical pI: Translated: 8.56; Mature: 8.56
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFDHGFIEVHDANQNNLQHVNVKIPKDAISVFVGRSGSGKSSLVFDTIAAESRRELNETF CCCCCEEEEEECCCCCEEEEEEECCHHHHHEEECCCCCCCCCEEEHHHHHHHHHHHHHHH PSFTQQYLPKYGQPDVGQIDHLPVAIVVEQKRIGKNARSTLATYTGIYSLLRLLFSRAGK HHHHHHHCCCCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC PFIGYSDTFSFNLPQGMCKTCQGLGYVDDIDVKKLIDPNKSLNQGAITFVSFGPDTWRWK CCCCCCCCEEECCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCHHHH RYAYSGLFDNDKRLGDYTKQEMDTLLYAPQQTLDHAPTKWPKTALYEGVVPRIRRSIIGK HHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC KEAEHHKTALAEIVTRMPCPTCHGTRLRPEVLTCLINQTNIAQVLQMDLVKVRHFLNGIQ HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH EPLVQDVIRELLRKIDSLIDIGLGYLSLDRPTETLSGGETQRIKIAKFLTSALVDMVYIL HHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHC DEPSVGLHPHDIELIKRAILRLKEKGNTILIVEHNPALIAIGDNIVEVGPGAGTTGGHIT CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCEEEECCCCCCCCCEEE FTGTYQALLDSDTLTGKLLKQPLTFRQPRPATSTISLQHIHRHNLKDVSVAVPLGIETVI EEEHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCEEEHHHHHHCCCCCEEEEECCCHHHHH SGVAGSGKSTLVSALRDQLTAPYIDLAQADIGANIRSAPATYLSILDPIRKVFADANHVA HHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH SSWFSYNGRGACPRCKGKGVTITNMAFMDPVVQTCEQCHGRRYNDQALSYTYHDKNISDV HHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHH LRMPITKAQNFFTDVPAIAAPLRNMARVGLDYLTLGQPLTTLSGGEKQRLKLAVELNRTG HHCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCCCHHHCCCCCCEEEEEEEEECCCE TLYLLDEPTAGLHLQDVKKLIQLFDELVADGNSLIIVEHNLEVISQADWLIDMGPDAGIY EEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCEEEECCCCCCCC GGQVRYTGTPENSMTVKQSRTGQAMKQYNQAPERQQNNRH CCEEEECCCCCCCEEEHHHHHHHHHHHHHCCHHHHHCCCC >Mature Secondary Structure MFDHGFIEVHDANQNNLQHVNVKIPKDAISVFVGRSGSGKSSLVFDTIAAESRRELNETF CCCCCEEEEEECCCCCEEEEEEECCHHHHHEEECCCCCCCCCEEEHHHHHHHHHHHHHHH PSFTQQYLPKYGQPDVGQIDHLPVAIVVEQKRIGKNARSTLATYTGIYSLLRLLFSRAGK HHHHHHHCCCCCCCCCCCCCCCCEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC PFIGYSDTFSFNLPQGMCKTCQGLGYVDDIDVKKLIDPNKSLNQGAITFVSFGPDTWRWK CCCCCCCCEEECCCHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEEEECCCCHHHH RYAYSGLFDNDKRLGDYTKQEMDTLLYAPQQTLDHAPTKWPKTALYEGVVPRIRRSIIGK HHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCC KEAEHHKTALAEIVTRMPCPTCHGTRLRPEVLTCLINQTNIAQVLQMDLVKVRHFLNGIQ HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH EPLVQDVIRELLRKIDSLIDIGLGYLSLDRPTETLSGGETQRIKIAKFLTSALVDMVYIL HHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHC DEPSVGLHPHDIELIKRAILRLKEKGNTILIVEHNPALIAIGDNIVEVGPGAGTTGGHIT CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCEEEECCCCCCCCCEEE FTGTYQALLDSDTLTGKLLKQPLTFRQPRPATSTISLQHIHRHNLKDVSVAVPLGIETVI EEEHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCEEEHHHHHHCCCCCEEEEECCCHHHHH SGVAGSGKSTLVSALRDQLTAPYIDLAQADIGANIRSAPATYLSILDPIRKVFADANHVA HHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHH SSWFSYNGRGACPRCKGKGVTITNMAFMDPVVQTCEQCHGRRYNDQALSYTYHDKNISDV HHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHH LRMPITKAQNFFTDVPAIAAPLRNMARVGLDYLTLGQPLTTLSGGEKQRLKLAVELNRTG HHCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCCCHHHCCCCCCEEEEEEEEECCCE TLYLLDEPTAGLHLQDVKKLIQLFDELVADGNSLIIVEHNLEVISQADWLIDMGPDAGIY EEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCEEEECCCCCCCC GGQVRYTGTPENSMTVKQSRTGQAMKQYNQAPERQQNNRH CCEEEECCCCCCCEEEHHHHHHHHHHHHHCCHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9537320 [H]