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The map label for this gene is mtnN [H]

Identifier: 116494779

GI number: 116494779

Start: 1266903

End: 1267613

Strand: Direct

Name: mtnN [H]

Synonym: LSEI_1288

Alternate gene names: 116494779

Gene position: 1266903-1267613 (Clockwise)

Preceding gene: 116494778

Following gene: 116494780

Centisome position: 43.76

GC content: 48.8

Gene sequence:

>711_bases
TTGATAAAAGTCGGCGTTATTTGTGCCATGGAAGAAGAAATCAGGACCTTACTGGCCAAACAGACTCAGCAACATGAAAC
GGTGATTGCCAGTCAACATTATTTTGAGGGCCAAATTGACGGGATTGATGTGATTTTGGTTCAGTCTGGTATTGGCAAGG
TTCAAGCGGCCATGACGGCGGCTTTGTTGTTGGGAACTTTTAAACCGGATGTTGTGATTAACACCGGAAGTGCCGGCGGT
ATTGGTCAAGGTCTGGCGATCGGTGATGTTGTTATTTCGAGCGGGGTTGCGTATCATGATGTAGATGCAACGGCTTTTGG
TTACTTACCAGGGCAGTTGCCACAACAGCCGCAAATTTTTGAAGCCGGTTTAGACTATGTGGCTAAAATTCAGGCGGCAG
CCAGCACAACCGGTTTAACGTCAAAGGTTGGCCTCATTGTGACAGGCGACAAGTTTGTTAACGGTCAGGATGCGATTGCG
GCAATTCTGAAAATCTATCCGCAGGCGTTAGCAAGCGAAATGGAAGGGGCGGCTATCGGTCAGGTGGCCAAAGAGTTCCA
TACCCCGTTTGTTGTCATCCGGGCAATGAGCGATGTCGCTGACGAGCAGTCCGGAGTGGATTTTGACAAATTTGTGATCA
AGGCGGGTGAACAAAGTGCCGCGATGCTTCTTAGCTTTTTTGCTCACCTACAGGCATCACCTCAGTCTTAG

Upstream 100 bases:

>100_bases
TAGCTATTCTTGGCACTTACCAGAAATGGCTACTGTAGCGCAAGCGCAGTGGAAGAAAGTTGATTCACTAATATTATAGA
AGAAAGAACGGAGCGATATT

Downstream 100 bases:

>100_bases
GAGTTGATTGTTAATATGCAACATGTTTATCTTGATAACGCGGCGACCACACCCATGGCCCCAGAAGTGATTCAGACCAT
GATGGACCAAATGGAGCACG

Product: nucleoside phosphorylase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MIKVGVICAMEEEIRTLLAKQTQQHETVIASQHYFEGQIDGIDVILVQSGIGKVQAAMTAALLLGTFKPDVVINTGSAGG
IGQGLAIGDVVISSGVAYHDVDATAFGYLPGQLPQQPQIFEAGLDYVAKIQAAASTTGLTSKVGLIVTGDKFVNGQDAIA
AILKIYPQALASEMEGAAIGQVAKEFHTPFVVIRAMSDVADEQSGVDFDKFVIKAGEQSAAMLLSFFAHLQASPQS

Sequences:

>Translated_236_residues
MIKVGVICAMEEEIRTLLAKQTQQHETVIASQHYFEGQIDGIDVILVQSGIGKVQAAMTAALLLGTFKPDVVINTGSAGG
IGQGLAIGDVVISSGVAYHDVDATAFGYLPGQLPQQPQIFEAGLDYVAKIQAAASTTGLTSKVGLIVTGDKFVNGQDAIA
AILKIYPQALASEMEGAAIGQVAKEFHTPFVVIRAMSDVADEQSGVDFDKFVIKAGEQSAAMLLSFFAHLQASPQS
>Mature_236_residues
MIKVGVICAMEEEIRTLLAKQTQQHETVIASQHYFEGQIDGIDVILVQSGIGKVQAAMTAALLLGTFKPDVVINTGSAGG
IGQGLAIGDVVISSGVAYHDVDATAFGYLPGQLPQQPQIFEAGLDYVAKIQAAASTTGLTSKVGLIVTGDKFVNGQDAIA
AILKIYPQALASEMEGAAIGQVAKEFHTPFVVIRAMSDVADEQSGVDFDKFVIKAGEQSAAMLLSFFAHLQASPQS

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=230, Percent_Identity=47.3913043478261, Blast_Score=187, Evalue=7e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 24696; Mature: 24696

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVGVICAMEEEIRTLLAKQTQQHETVIASQHYFEGQIDGIDVILVQSGIGKVQAAMTA
CEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHH
ALLLGTFKPDVVINTGSAGGIGQGLAIGDVVISSGVAYHDVDATAFGYLPGQLPQQPQIF
HHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCEEECCCCCEECCCCCCCCCCCHHH
EAGLDYVAKIQAAASTTGLTSKVGLIVTGDKFVNGQDAIAAILKIYPQALASEMEGAAIG
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
QVAKEFHTPFVVIRAMSDVADEQSGVDFDKFVIKAGEQSAAMLLSFFAHLQASPQS
HHHHHHCCHHHEEHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIKVGVICAMEEEIRTLLAKQTQQHETVIASQHYFEGQIDGIDVILVQSGIGKVQAAMTA
CEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHH
ALLLGTFKPDVVINTGSAGGIGQGLAIGDVVISSGVAYHDVDATAFGYLPGQLPQQPQIF
HHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHCCCEEECCCCCEECCCCCCCCCCCHHH
EAGLDYVAKIQAAASTTGLTSKVGLIVTGDKFVNGQDAIAAILKIYPQALASEMEGAAIG
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
QVAKEFHTPFVVIRAMSDVADEQSGVDFDKFVIKAGEQSAAMLLSFFAHLQASPQS
HHHHHHCCHHHEEHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA