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The map label for this gene is ftsA [H]

Identifier: 116494765

GI number: 116494765

Start: 1252664

End: 1254010

Strand: Direct

Name: ftsA [H]

Synonym: LSEI_1274

Alternate gene names: 116494765

Gene position: 1252664-1254010 (Clockwise)

Preceding gene: 116494764

Following gene: 116494766

Centisome position: 43.27

GC content: 48.92

Gene sequence:

>1347_bases
ATGGATAATCAAGGTATTTACGTTGGACTTGATATCGGAACCACCTCAATAAAAGTCATTGTTGCCGAAACAGTAAAGGG
ACAAATGAATGTTATTGGTGTGGGAAGTCAGCGATCGGAAGGCGTGAGCCGCGGGGTGATCGTTGATATCGATAAGGCAG
TTGCCGTCATTCGTGCGGCCGTTGCCCAAGCTGAAGACAAGGCAAATATCAAGATCGATCGGGTCGTTGCTGGCATTCCC
GCCAACATGCTGCAGATTGAACAAGTTTCCGGGATGATCGCGGTCGGTGAAGAGAATAAAGAAATTTCCGACAACGATGT
TCGCAGCGTGGCAGCGGCAGCATTGGTCCGCAACTTACCACCAGAGCGTGAAACATTATCATTAGTCCCGACCGAGTTTA
TCGTAGATGGTTTTGATGATATTAAAGATCCGCGTGGTATGTTGGGCGTTCGGCTTGAGATGCGTGGCATCATGTTAACT
GTTCCTAAGACCGTGATTCATAACACGAAGAAAGCCATTGAAAAGGCGGGTCTTCGAGTTGGCGGTTTGGTGATTTCGCC
TTTGGCCATTGGTCGTTTGGCCTTAACCGATGGTGAACAAGATTTTGGCACTGTTTTGATTGACATGGGTGGTGGTCAAA
GCACCGCTGCCGTGATCCATGACCGTAAGCTTAAGTTTACGTCGGTGGATCAAGAAGGCGGCGAGTATATCACTAAGGAT
ATTTCAGTTGTCCTCAACACGAGTTTTACGGACGCTGAGAAACTCAAGCGTGAGTATGGCAATGCTGATTCACTGGCAAC
GAGTGAGGAAGAGACTTTTCCTGTAACGGTTGTTGGCAAACACGAGCCAGCGATGATCTCTGAAAAATACCTTTCCGAGA
TTATCGAGGCGCGAGTGGCGCAAATCTTTAAACGTCTGAACAAAGCGTTGGACGCTGTCAATGCGCTTGATTTACCCGGC
GGCATTGTGATTACTGGCGGCACTACGGCGTTGCCAGGCGTGACGGAATTGGCTCAGGACATTTTCGGCCGACCGGTCAA
ACGGTTTATTCCTGATGATATGGGGTTGCGTCACCCATCCTTTACTGAAGGGCTTGCCCTTATCAAATATGCTGCCCAGA
TGACAGATATTGAAATGCTGGTCTCCAGCGTCTTGCCGACACCATTCATGGTTGATGGCGCAGATGTCCGTCCACAACCA
CAAAGTAAGCAGCCAGAGCAACCGGCTGCCGCTGTGGACCAAGGCAATCAGCGATTACTTAAGCGCAAGCAGGAAAAACA
ACCGGATAAACCAAAATCCAAGGAGCCTTCAGCATTACGCCGGTTCTTTGGCAATTTCTTTGAATAA

Upstream 100 bases:

>100_bases
GTTTGTTTTCTCAAGGCAAATCGAGTGTGTTACACTGATAATGGCACCATTCAAATATGAAATTAACCTATTAAACGTTA
CACAAGGAGGTTCCCGATAC

Downstream 100 bases:

>100_bases
ATCTCGATCCTAGGAGGAACACGAATGGATTTTCAAATGGACGCACAAAATGAAAAAGGCGCCAACATTAAAGTAATCGG
TGTCGGCGGTGCAGGCGGCA

Product: ATPase for cell division

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MDNQGIYVGLDIGTTSIKVIVAETVKGQMNVIGVGSQRSEGVSRGVIVDIDKAVAVIRAAVAQAEDKANIKIDRVVAGIP
ANMLQIEQVSGMIAVGEENKEISDNDVRSVAAAALVRNLPPERETLSLVPTEFIVDGFDDIKDPRGMLGVRLEMRGIMLT
VPKTVIHNTKKAIEKAGLRVGGLVISPLAIGRLALTDGEQDFGTVLIDMGGGQSTAAVIHDRKLKFTSVDQEGGEYITKD
ISVVLNTSFTDAEKLKREYGNADSLATSEEETFPVTVVGKHEPAMISEKYLSEIIEARVAQIFKRLNKALDAVNALDLPG
GIVITGGTTALPGVTELAQDIFGRPVKRFIPDDMGLRHPSFTEGLALIKYAAQMTDIEMLVSSVLPTPFMVDGADVRPQP
QSKQPEQPAAAVDQGNQRLLKRKQEKQPDKPKSKEPSALRRFFGNFFE

Sequences:

>Translated_448_residues
MDNQGIYVGLDIGTTSIKVIVAETVKGQMNVIGVGSQRSEGVSRGVIVDIDKAVAVIRAAVAQAEDKANIKIDRVVAGIP
ANMLQIEQVSGMIAVGEENKEISDNDVRSVAAAALVRNLPPERETLSLVPTEFIVDGFDDIKDPRGMLGVRLEMRGIMLT
VPKTVIHNTKKAIEKAGLRVGGLVISPLAIGRLALTDGEQDFGTVLIDMGGGQSTAAVIHDRKLKFTSVDQEGGEYITKD
ISVVLNTSFTDAEKLKREYGNADSLATSEEETFPVTVVGKHEPAMISEKYLSEIIEARVAQIFKRLNKALDAVNALDLPG
GIVITGGTTALPGVTELAQDIFGRPVKRFIPDDMGLRHPSFTEGLALIKYAAQMTDIEMLVSSVLPTPFMVDGADVRPQP
QSKQPEQPAAAVDQGNQRLLKRKQEKQPDKPKSKEPSALRRFFGNFFE
>Mature_448_residues
MDNQGIYVGLDIGTTSIKVIVAETVKGQMNVIGVGSQRSEGVSRGVIVDIDKAVAVIRAAVAQAEDKANIKIDRVVAGIP
ANMLQIEQVSGMIAVGEENKEISDNDVRSVAAAALVRNLPPERETLSLVPTEFIVDGFDDIKDPRGMLGVRLEMRGIMLT
VPKTVIHNTKKAIEKAGLRVGGLVISPLAIGRLALTDGEQDFGTVLIDMGGGQSTAAVIHDRKLKFTSVDQEGGEYITKD
ISVVLNTSFTDAEKLKREYGNADSLATSEEETFPVTVVGKHEPAMISEKYLSEIIEARVAQIFKRLNKALDAVNALDLPG
GIVITGGTTALPGVTELAQDIFGRPVKRFIPDDMGLRHPSFTEGLALIKYAAQMTDIEMLVSSVLPTPFMVDGADVRPQP
QSKQPEQPAAAVDQGNQRLLKRKQEKQPDKPKSKEPSALRRFFGNFFE

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=382, Percent_Identity=29.3193717277487, Blast_Score=172, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494
- InterPro:   IPR021873 [H]

Pfam domain/function: PF11983 DUF3484; PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 48379; Mature: 48379

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS01036 HSP70_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNQGIYVGLDIGTTSIKVIVAETVKGQMNVIGVGSQRSEGVSRGVIVDIDKAVAVIRAA
CCCCCEEEEEEECCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHH
VAQAEDKANIKIDRVVAGIPANMLQIEQVSGMIAVGEENKEISDNDVRSVAAAALVRNLP
HHHCCCCCCEEEEHEEECCCHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
PERETLSLVPTEFIVDGFDDIKDPRGMLGVRLEMRGIMLTVPKTVIHNTKKAIEKAGLRV
CCCHHEECCCHHHHHCCHHHCCCCCCCEEEEEEECCEEEECCHHHHHHHHHHHHHCCCEE
GGLVISPLAIGRLALTDGEQDFGTVLIDMGGGQSTAAVIHDRKLKFTSVDQEGGEYITKD
CCEEECCHHHCEEEECCCCCCCCEEEEECCCCCCEEEEEECCCEEEEECCCCCCHHHHHC
ISVVLNTSFTDAEKLKREYGNADSLATSEEETFPVTVVGKHEPAMISEKYLSEIIEARVA
EEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
QIFKRLNKALDAVNALDLPGGIVITGGTTALPGVTELAQDIFGRPVKRFIPDDMGLRHPS
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCC
FTEGLALIKYAAQMTDIEMLVSSVLPTPFMVDGADVRPQPQSKQPEQPAAAVDQGNQRLL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCHHHHCCCHHHHH
KRKQEKQPDKPKSKEPSALRRFFGNFFE
HHHHHCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDNQGIYVGLDIGTTSIKVIVAETVKGQMNVIGVGSQRSEGVSRGVIVDIDKAVAVIRAA
CCCCCEEEEEEECCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHH
VAQAEDKANIKIDRVVAGIPANMLQIEQVSGMIAVGEENKEISDNDVRSVAAAALVRNLP
HHHCCCCCCEEEEHEEECCCHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
PERETLSLVPTEFIVDGFDDIKDPRGMLGVRLEMRGIMLTVPKTVIHNTKKAIEKAGLRV
CCCHHEECCCHHHHHCCHHHCCCCCCCEEEEEEECCEEEECCHHHHHHHHHHHHHCCCEE
GGLVISPLAIGRLALTDGEQDFGTVLIDMGGGQSTAAVIHDRKLKFTSVDQEGGEYITKD
CCEEECCHHHCEEEECCCCCCCCEEEEECCCCCCEEEEEECCCEEEEECCCCCCHHHHHC
ISVVLNTSFTDAEKLKREYGNADSLATSEEETFPVTVVGKHEPAMISEKYLSEIIEARVA
EEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHH
QIFKRLNKALDAVNALDLPGGIVITGGTTALPGVTELAQDIFGRPVKRFIPDDMGLRHPS
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCC
FTEGLALIKYAAQMTDIEMLVSSVLPTPFMVDGADVRPQPQSKQPEQPAAAVDQGNQRLL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCHHHHCCCHHHHH
KRKQEKQPDKPKSKEPSALRRFFGNFFE
HHHHHCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10520745 [H]