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The map label for this gene is mreB [H]

Identifier: 116494747

GI number: 116494747

Start: 1234852

End: 1235853

Strand: Direct

Name: mreB [H]

Synonym: LSEI_1255

Alternate gene names: 116494747

Gene position: 1234852-1235853 (Clockwise)

Preceding gene: 116494746

Following gene: 116494748

Centisome position: 42.65

GC content: 47.8

Gene sequence:

>1002_bases
TTGTTTGGATTTGGATCAAAAAATATCGGGATCGATCTTGGCACTGCAAATACCTTGGTTTACGTTGACGGTAAAGGCAT
CGTTTTAAACGAACCTTCCGTTGTCGCGAAGAATACCCAAACGGAAGAAGTCATTGCGGTTGGTGAAGAAGCTCGCGACA
TGATCGGTCGTACCCCGACCAATATCGTGGCGATCCGCCCAATGAAAGATGGGGTCATCGCTGACTACGATACAACGGCA
GCCATGTTGAAATACTTCATGCAAAAGGCGCTCGGCAACGGTAGCCATCCGCAGGTCATGATTTGTGTGCCTAGCGGTGT
GACCGAAGTTGAAAAACGCGCCGTGATTGATGCGGCTAAAGTTGCTGGTGCACGCGATGCATTCGTCATTGAGGAACCTT
ATGCTGCTGCGATCGGTGCTGGCTTGCCAGTTATGGATCCTACCGGCAGCATGGTTGTTGATATTGGCGGCGGCACGACT
GACGTGGCGACCATCTCACTTGGCGGTATCGTGTCCAGTCGTTCTATTCGAGTGGCCGGTGACAAGTTTGATGAAGCGAT
CATCAATCACTTACGGCAGAATTTCAACCTGTTAATCGGTGAGCGAACAGCTGAAGCCATGAAGATTCAGATTGGCTCAG
CATCTGTTGAAAAGGCAAAAGATATTGACGGCATGACGGTTCGCGGTCGTGATTTGTTGAGTGGTTTACCGAAGACAATC
GAAATTTCAGCGACTGACATTGCCAGTGCCATTCATGAAAATGTTCTTGATATCATTACAGCAATTAAAGAGACGCTTGA
AGAAACTTCTCCAGAAATTGCTGCCGATGTCATTGATCATGGGATTGTTTTAACAGGTGGCGGTGCCTTATTGAAGCACT
TGCCGGATGTCATTTCGGATGAAACCAAGGTACCGGTCTTCATTGCCCAAGATCCATTGGATTGTGTTGCCATCGGTACT
GGCGAGTCATTGAAGAATATTGATGTCCTAAAGAAGCGTTAA

Upstream 100 bases:

>100_bases
TCTGGCATGAAAATCGGGTAGTTTCACATTTTGTCACAGAAATAAATATGCTATAATGCATGGAGTTATACGAAATGAGT
CAGCATAAGGGGAGAACGTC

Downstream 100 bases:

>100_bases
CAGCCCATAAATGAAGATGGTTCGTGTGTGGCAAGAGGCTGGGATGATTTGATCCTGGCCTTTTTTCGCGAGTATGACGG
AGGAACCAATGCAGAAATTC

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MFGFGSKNIGIDLGTANTLVYVDGKGIVLNEPSVVAKNTQTEEVIAVGEEARDMIGRTPTNIVAIRPMKDGVIADYDTTA
AMLKYFMQKALGNGSHPQVMICVPSGVTEVEKRAVIDAAKVAGARDAFVIEEPYAAAIGAGLPVMDPTGSMVVDIGGGTT
DVATISLGGIVSSRSIRVAGDKFDEAIINHLRQNFNLLIGERTAEAMKIQIGSASVEKAKDIDGMTVRGRDLLSGLPKTI
EISATDIASAIHENVLDIITAIKETLEETSPEIAADVIDHGIVLTGGGALLKHLPDVISDETKVPVFIAQDPLDCVAIGT
GESLKNIDVLKKR

Sequences:

>Translated_333_residues
MFGFGSKNIGIDLGTANTLVYVDGKGIVLNEPSVVAKNTQTEEVIAVGEEARDMIGRTPTNIVAIRPMKDGVIADYDTTA
AMLKYFMQKALGNGSHPQVMICVPSGVTEVEKRAVIDAAKVAGARDAFVIEEPYAAAIGAGLPVMDPTGSMVVDIGGGTT
DVATISLGGIVSSRSIRVAGDKFDEAIINHLRQNFNLLIGERTAEAMKIQIGSASVEKAKDIDGMTVRGRDLLSGLPKTI
EISATDIASAIHENVLDIITAIKETLEETSPEIAADVIDHGIVLTGGGALLKHLPDVISDETKVPVFIAQDPLDCVAIGT
GESLKNIDVLKKR
>Mature_333_residues
MFGFGSKNIGIDLGTANTLVYVDGKGIVLNEPSVVAKNTQTEEVIAVGEEARDMIGRTPTNIVAIRPMKDGVIADYDTTA
AMLKYFMQKALGNGSHPQVMICVPSGVTEVEKRAVIDAAKVAGARDAFVIEEPYAAAIGAGLPVMDPTGSMVVDIGGGTT
DVATISLGGIVSSRSIRVAGDKFDEAIINHLRQNFNLLIGERTAEAMKIQIGSASVEKAKDIDGMTVRGRDLLSGLPKTI
EISATDIASAIHENVLDIITAIKETLEETSPEIAADVIDHGIVLTGGGALLKHLPDVISDETKVPVFIAQDPLDCVAIGT
GESLKNIDVLKKR

Specific function: Involved in formation of the rod shape of the cell [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=334, Percent_Identity=52.6946107784431, Blast_Score=346, Evalue=1e-96,
Organism=Caenorhabditis elegans, GI17507981, Length=376, Percent_Identity=25.531914893617, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 35002; Mature: 35002

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGFGSKNIGIDLGTANTLVYVDGKGIVLNEPSVVAKNTQTEEVIAVGEEARDMIGRTPT
CCCCCCCCCEEEECCCCEEEEECCCEEEECCCCEEECCCCCHHHEEECHHHHHHHCCCCC
NIVAIRPMKDGVIADYDTTAAMLKYFMQKALGNGSHPQVMICVPSGVTEVEKRAVIDAAK
CEEEEEECCCCEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHH
VAGARDAFVIEEPYAAAIGAGLPVMDPTGSMVVDIGGGTTDVATISLGGIVSSRSIRVAG
HCCCCCEEEEECCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEECCEECCCEEEECC
DKFDEAIINHLRQNFNLLIGERTAEAMKIQIGSASVEKAKDIDGMTVRGRDLLSGLPKTI
CHHHHHHHHHHHHCCEEEEECCCCEEEEEEECCCCHHHHHCCCCEEECCHHHHHCCCCEE
EISATDIASAIHENVLDIITAIKETLEETSPEIAADVIDHGIVLTGGGALLKHLPDVISD
EEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCHHHHHHHHHHHCC
ETKVPVFIAQDPLDCVAIGTGESLKNIDVLKKR
CCCCEEEEECCCCCEEEECCCCCCCCCHHHCCC
>Mature Secondary Structure
MFGFGSKNIGIDLGTANTLVYVDGKGIVLNEPSVVAKNTQTEEVIAVGEEARDMIGRTPT
CCCCCCCCCEEEECCCCEEEEECCCEEEECCCCEEECCCCCHHHEEECHHHHHHHCCCCC
NIVAIRPMKDGVIADYDTTAAMLKYFMQKALGNGSHPQVMICVPSGVTEVEKRAVIDAAK
CEEEEEECCCCEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHH
VAGARDAFVIEEPYAAAIGAGLPVMDPTGSMVVDIGGGTTDVATISLGGIVSSRSIRVAG
HCCCCCEEEEECCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEEECCEECCCEEEECC
DKFDEAIINHLRQNFNLLIGERTAEAMKIQIGSASVEKAKDIDGMTVRGRDLLSGLPKTI
CHHHHHHHHHHHHCCEEEEECCCCEEEEEEECCCCHHHHHCCCCEEECCHHHHHCCCCEE
EISATDIASAIHENVLDIITAIKETLEETSPEIAADVIDHGIVLTGGGALLKHLPDVISD
EEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEECCHHHHHHHHHHHCC
ETKVPVFIAQDPLDCVAIGTGESLKNIDVLKKR
CCCCEEEEECCCCCEEEECCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377; 8387996 [H]