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The map label for this gene is 116494699

Identifier: 116494699

GI number: 116494699

Start: 1186016

End: 1186744

Strand: Direct

Name: 116494699

Synonym: LSEI_1205

Alternate gene names: NA

Gene position: 1186016-1186744 (Clockwise)

Preceding gene: 116494698

Following gene: 116494700

Centisome position: 40.96

GC content: 44.03

Gene sequence:

>729_bases
GTGATCTACATTTTAGGCAGTATTGGTGCAGGAAAAACGTCGCTGACAAAAGTTTTGTCAGAAGATATGCAGGCACCGGC
ATATTATGAAGATGTTGAAGGTAATGGCATGATCGCCAATATGTTGCAAAAATTTTATGGTGCAGGCGTTGAGAGTCGTA
AGCGAACCGGCGCGATGTTGCAGATTGCATTTCTCACGTTCCGTTACCAGCAATTGAAGAAGGCTGTGACCCAAGAAAAC
GCGATCATGGATTCTTCGCTTGAATCAGACTTCGTGATGGCCTCGCAGTTGCATAAACACGGTGAAATTGATGATGTTGA
TTTCAACGTTTATGTGACACTGTCTCAAGAGATGCAAAGTAATGTCAATGGCAGTCCTTGGAACGGTTTTCCTGATCTAG
CAGTTTATCTGAAAATTGATCCAGATCACGAAATTGACGAAATTCAAAGTCGTGGTCGCGATATGGAAGATATTCGCGAA
AAGCCGGAGTTGGTCGATTACTATCGGCGTGTCAACACAGCTTATCGTGATTGGGCAAAGGGTTATACGCGCTCGTCTAT
GATTACAATTGATCGTGATCGTTATGACTTTATGCACTCAGCAGCTGACCGTGCCAGTGTGTTGGATCAAATTGAAACCA
AGCTTGTTGATCTCGGCAAATTATCTCCGCAAGCATTTGATGCGTTGCAAGCGCAACATGCAGATGGGCCGATTTCTAAG
TTTGCATGA

Upstream 100 bases:

>100_bases
GCAGCTGGGTCTAAAAACGATCTAAGTGGTGCTTTAGCTGTGTTTGTGGTAATGTTTGTTGTTGGCGCAACATAATAAAC
ATAATTGAGGAGCGAGATCT

Downstream 100 bases:

>100_bases
TTTCCAGTTAAATTGTTAGAAACAACGACCTGTGTCATCCTCATTTTTAGGGGATAACACAGGTCGTTTTTGATTTGTTT
CATAAAACATGTTCACAAAC

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGK; DGUO kinase; Deoxynucleoside kinase complex I F-component [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MIYILGSIGAGKTSLTKVLSEDMQAPAYYEDVEGNGMIANMLQKFYGAGVESRKRTGAMLQIAFLTFRYQQLKKAVTQEN
AIMDSSLESDFVMASQLHKHGEIDDVDFNVYVTLSQEMQSNVNGSPWNGFPDLAVYLKIDPDHEIDEIQSRGRDMEDIRE
KPELVDYYRRVNTAYRDWAKGYTRSSMITIDRDRYDFMHSAADRASVLDQIETKLVDLGKLSPQAFDALQAQHADGPISK
FA

Sequences:

>Translated_242_residues
MIYILGSIGAGKTSLTKVLSEDMQAPAYYEDVEGNGMIANMLQKFYGAGVESRKRTGAMLQIAFLTFRYQQLKKAVTQEN
AIMDSSLESDFVMASQLHKHGEIDDVDFNVYVTLSQEMQSNVNGSPWNGFPDLAVYLKIDPDHEIDEIQSRGRDMEDIRE
KPELVDYYRRVNTAYRDWAKGYTRSSMITIDRDRYDFMHSAADRASVLDQIETKLVDLGKLSPQAFDALQAQHADGPISK
FA
>Mature_242_residues
MIYILGSIGAGKTSLTKVLSEDMQAPAYYEDVEGNGMIANMLQKFYGAGVESRKRTGAMLQIAFLTFRYQQLKKAVTQEN
AIMDSSLESDFVMASQLHKHGEIDDVDFNVYVTLSQEMQSNVNGSPWNGFPDLAVYLKIDPDHEIDEIQSRGRDMEDIRE
KPELVDYYRRVNTAYRDWAKGYTRSSMITIDRDRYDFMHSAADRASVLDQIETKLVDLGKLSPQAFDALQAQHADGPISK
FA

Specific function: DGK/DAK plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism [H]

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 27389; Mature: 27389

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYILGSIGAGKTSLTKVLSEDMQAPAYYEDVEGNGMIANMLQKFYGAGVESRKRTGAML
CEEEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCHHHHHCHHH
QIAFLTFRYQQLKKAVTQENAIMDSSLESDFVMASQLHKHGEIDDVDFNVYVTLSQEMQS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHC
NVNGSPWNGFPDLAVYLKIDPDHEIDEIQSRGRDMEDIREKPELVDYYRRVNTAYRDWAK
CCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHH
GYTRSSMITIDRDRYDFMHSAADRASVLDQIETKLVDLGKLSPQAFDALQAQHADGPISK
CCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHH
FA
CC
>Mature Secondary Structure
MIYILGSIGAGKTSLTKVLSEDMQAPAYYEDVEGNGMIANMLQKFYGAGVESRKRTGAML
CEEEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCHHHHHCHHH
QIAFLTFRYQQLKKAVTQENAIMDSSLESDFVMASQLHKHGEIDDVDFNVYVTLSQEMQS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHC
NVNGSPWNGFPDLAVYLKIDPDHEIDEIQSRGRDMEDIREKPELVDYYRRVNTAYRDWAK
CCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHH
GYTRSSMITIDRDRYDFMHSAADRASVLDQIETKLVDLGKLSPQAFDALQAQHADGPISK
CCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHH
FA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7896798; 8172906 [H]