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The map label for this gene is atpD

Identifier: 116494662

GI number: 116494662

Start: 1150166

End: 1151632

Strand: Direct

Name: atpD

Synonym: LSEI_1166

Alternate gene names: 116494662

Gene position: 1150166-1151632 (Clockwise)

Preceding gene: 116494661

Following gene: 116494663

Centisome position: 39.73

GC content: 50.44

Gene sequence:

>1467_bases
ATGCCAAATTCAACTGGTAAAATCGCGCAAGTGATCGGTCCTGTTGTCGACGTAGCCTTCCCAATCAATGGCGATCTGCC
AGAAATCAATAACGCCTTGACCGTTGCCAAGAAGGATGGCTCCCAGCTTGTGCTGGAAGTTGCCTTGGAACTTGGTGATG
GCGTGATGCGGACTATTGCGATGGATTCCACCGATGGTCTGCAACGCAACATGGCGGTTCAAGATACTGGCGGTCCGATC
TCAGTCCCTGTCGGAAAAGACACACTGGGTCGGGTGTTCAATGTGTTGGGCGACCCCATCGATGGCGGTGAAGCCTTTGG
ACCGGATCATCGGCGCGACAGCATCCATCGTGATGCGCCAAAATTCGAAGATTTGAATACCAGTTCAGAAATCTTGGAAA
CTGGCATCAAAGTCATCGATTTGCTCGAACCTTACCTGCGTGGTGGGAAGGTCGGACTCTTCGGCGGTGCTGGTGTCGGC
AAAACCGTTTTGATTCAGGAACTGATTCATAATATTGCCGAGGAACACGGCGGCATCTCCGTTTTCACTGGGGTCGGCGA
ACGAACCCGTGAAGGGAACGACCTTTACTTCGAAATGAAGGAAAGTGGCGTTCTGGAGAATACAGCCATGGTCTTTGGTC
AGATGAACGAGCCGCCTGGTGCCCGGATGCGGGTTGCCTTGACCGGATTGACGATCGCGGAATACTTCCGTGATGTTGAA
GGTCAGGATGTCCTGCTGTTTATCGACAACATTTTCCGGTTCACTCAGGCCGGTTCCGAAGTTTCTGCTTTACTTGGCCG
GATTCCATCAGCTGTTGGTTATCAGCCAACGCTGGCAACAGAAATGGGTCAGTTGCAGGAACGGATTACATCGACTAAAA
AAGGTTCAGTTACATCGATTCAGGCAATTTATGTGCCTGCTGATGACTACACTGACCCTGCGCCGGCAACGACTTTTGCG
CATTTGGATGCAACGACCAACTTGGAACGGCGTCTGACTGAGCAAGGGATTTATCCCGCCGTTGATCCGCTGGAATCATC
TTCTAGTGCATTGACGCCGGAAATTGTCGGTGATGAACATTATAAAGTCGCTACCGAAGTGCAACAAGTTTTGCAGCGGT
ATCGTGAGTTACAAGATATCATCTCTATTTTGGGGATGGATGAATTGTCTGACGAAGAAAAGGTCGTTGTGGCCCGTGCT
CGCCGGATTCAGTTCTTCTTGTCACAAAACTTTAACGTTGCGGAACGGTTCACTGGCCAGCCAGGTTCATATGTGCCGGT
TGAAGAAACGGTTAAAGGCTTTAAAGCTATCTTGGATGGCAAATACGACGATTACCCTGAAGATGCCTTCCGTTCGGTCG
GTCGCATCGAAGAAGTTGTCGAAAAGGCTAAGAAGATGGGCTTTGCTCCTGACGATCAGAATACGGATGCTGACGAAAAG
CCGGCTGCACAAGCTGCAGCTAACTAA

Upstream 100 bases:

>100_bases
TGAACGCAATGACCAAAGTGCGGTCATCACGTTCAGGCCCACTTACACTCCGGTTTCTAAACGCACCAGCTCGCGCTCAA
TTTACAACAGGAGGACGAAA

Downstream 100 bases:

>100_bases
GGAGGCGACGCGTTTTGGCTGAAACGAGCAACGTTCTTCGGGTCAACATCGTGACGCCTGATGGGTTAGTATACGATCAT
CACGCCAGGATGCTAGTTGT

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MPNSTGKIAQVIGPVVDVAFPINGDLPEINNALTVAKKDGSQLVLEVALELGDGVMRTIAMDSTDGLQRNMAVQDTGGPI
SVPVGKDTLGRVFNVLGDPIDGGEAFGPDHRRDSIHRDAPKFEDLNTSSEILETGIKVIDLLEPYLRGGKVGLFGGAGVG
KTVLIQELIHNIAEEHGGISVFTGVGERTREGNDLYFEMKESGVLENTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVE
GQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATTFA
HLDATTNLERRLTEQGIYPAVDPLESSSSALTPEIVGDEHYKVATEVQQVLQRYRELQDIISILGMDELSDEEKVVVARA
RRIQFFLSQNFNVAERFTGQPGSYVPVEETVKGFKAILDGKYDDYPEDAFRSVGRIEEVVEKAKKMGFAPDDQNTDADEK
PAAQAAAN

Sequences:

>Translated_488_residues
MPNSTGKIAQVIGPVVDVAFPINGDLPEINNALTVAKKDGSQLVLEVALELGDGVMRTIAMDSTDGLQRNMAVQDTGGPI
SVPVGKDTLGRVFNVLGDPIDGGEAFGPDHRRDSIHRDAPKFEDLNTSSEILETGIKVIDLLEPYLRGGKVGLFGGAGVG
KTVLIQELIHNIAEEHGGISVFTGVGERTREGNDLYFEMKESGVLENTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVE
GQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATTFA
HLDATTNLERRLTEQGIYPAVDPLESSSSALTPEIVGDEHYKVATEVQQVLQRYRELQDIISILGMDELSDEEKVVVARA
RRIQFFLSQNFNVAERFTGQPGSYVPVEETVKGFKAILDGKYDDYPEDAFRSVGRIEEVVEKAKKMGFAPDDQNTDADEK
PAAQAAAN
>Mature_487_residues
PNSTGKIAQVIGPVVDVAFPINGDLPEINNALTVAKKDGSQLVLEVALELGDGVMRTIAMDSTDGLQRNMAVQDTGGPIS
VPVGKDTLGRVFNVLGDPIDGGEAFGPDHRRDSIHRDAPKFEDLNTSSEILETGIKVIDLLEPYLRGGKVGLFGGAGVGK
TVLIQELIHNIAEEHGGISVFTGVGERTREGNDLYFEMKESGVLENTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEG
QDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATTFAH
LDATTNLERRLTEQGIYPAVDPLESSSSALTPEIVGDEHYKVATEVQQVLQRYRELQDIISILGMDELSDEEKVVVARAR
RIQFFLSQNFNVAERFTGQPGSYVPVEETVKGFKAILDGKYDDYPEDAFRSVGRIEEVVEKAKKMGFAPDDQNTDADEKP
AAQAAAN

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI32189394, Length=471, Percent_Identity=66.4543524416136, Blast_Score=609, Evalue=1e-174,
Organism=Homo sapiens, GI19913424, Length=310, Percent_Identity=28.0645161290323, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI19913428, Length=344, Percent_Identity=24.4186046511628, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI19913426, Length=390, Percent_Identity=25.1282051282051, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI50345984, Length=316, Percent_Identity=26.5822784810127, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4757810, Length=316, Percent_Identity=26.5822784810127, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1790170, Length=463, Percent_Identity=65.4427645788337, Blast_Score=601, Evalue=1e-173,
Organism=Escherichia coli, GI1788251, Length=319, Percent_Identity=30.4075235109718, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1790172, Length=351, Percent_Identity=28.4900284900285, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=472, Percent_Identity=63.5593220338983, Blast_Score=591, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI17565854, Length=347, Percent_Identity=28.8184438040346, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17510931, Length=404, Percent_Identity=24.2574257425743, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=405, Percent_Identity=24.1975308641975, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71988080, Length=386, Percent_Identity=26.4248704663212, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71988063, Length=386, Percent_Identity=26.4248704663212, Blast_Score=93, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71988074, Length=411, Percent_Identity=25.0608272506083, Blast_Score=79, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322581, Length=463, Percent_Identity=69.3304535637149, Blast_Score=621, Evalue=1e-179,
Organism=Saccharomyces cerevisiae, GI6319603, Length=400, Percent_Identity=25.25, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6319370, Length=380, Percent_Identity=26.8421052631579, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320016, Length=260, Percent_Identity=26.1538461538462, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24638766, Length=468, Percent_Identity=67.0940170940171, Blast_Score=609, Evalue=1e-174,
Organism=Drosophila melanogaster, GI28574560, Length=467, Percent_Identity=65.524625267666, Blast_Score=597, Evalue=1e-171,
Organism=Drosophila melanogaster, GI20129479, Length=346, Percent_Identity=27.1676300578035, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24583988, Length=480, Percent_Identity=25.4166666666667, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24583986, Length=480, Percent_Identity=25.4166666666667, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24583984, Length=480, Percent_Identity=25.4166666666667, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24583992, Length=477, Percent_Identity=25.5765199161426, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI281361666, Length=379, Percent_Identity=24.2744063324538, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646341, Length=379, Percent_Identity=24.2744063324538, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17136796, Length=379, Percent_Identity=24.2744063324538, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24658560, Length=317, Percent_Identity=27.1293375394322, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24638768, Length=93, Percent_Identity=55.9139784946236, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPB_LACC3 (Q03A18)

Other databases:

- EMBL:   CP000423
- RefSeq:   YP_806396.1
- ProteinModelPortal:   Q03A18
- SMR:   Q03A18
- STRING:   Q03A18
- GeneID:   4420202
- GenomeReviews:   CP000423_GR
- KEGG:   lca:LSEI_1166
- eggNOG:   COG0055
- HOGENOM:   HBG565875
- OMA:   IGQEHYD
- ProtClustDB:   PRK09280
- BioCyc:   LCAS321967:LSEI_1166-MONOMER
- HAMAP:   MF_01347
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF8
- SMART:   SM00382
- TIGRFAMs:   TIGR01039

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 52926; Mature: 52795

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNSTGKIAQVIGPVVDVAFPINGDLPEINNALTVAKKDGSQLVLEVALELGDGVMRTIA
CCCCCHHHHHHHHHHHHEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHC
MDSTDGLQRNMAVQDTGGPISVPVGKDTLGRVFNVLGDPIDGGEAFGPDHRRDSIHRDAP
CCCCCCHHHCCEEECCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHCCCC
KFEDLNTSSEILETGIKVIDLLEPYLRGGKVGLFGGAGVGKTVLIQELIHNIAEEHGGIS
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEE
VFTGVGERTREGNDLYFEMKESGVLENTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVE
EEECCCCCCCCCCCEEEEECCCCCHHHHHHHEECCCCCCCCEEEEEEHHHHHHHHHHCCC
GQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSVTSI
CCEEEEEHHHHHHHHHCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
QAIYVPADDYTDPAPATTFAHLDATTNLERRLTEQGIYPAVDPLESSSSALTPEIVGDEH
EEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCCCH
YKVATEVQQVLQRYRELQDIISILGMDELSDEEKVVVARARRIQFFLSQNFNVAERFTGQ
HHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCC
PGSYVPVEETVKGFKAILDGKYDDYPEDAFRSVGRIEEVVEKAKKMGFAPDDQNTDADEK
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PAAQAAAN
CCHHHCCC
>Mature Secondary Structure 
PNSTGKIAQVIGPVVDVAFPINGDLPEINNALTVAKKDGSQLVLEVALELGDGVMRTIA
CCCCHHHHHHHHHHHHEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHC
MDSTDGLQRNMAVQDTGGPISVPVGKDTLGRVFNVLGDPIDGGEAFGPDHRRDSIHRDAP
CCCCCCHHHCCEEECCCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHCCHHCCCC
KFEDLNTSSEILETGIKVIDLLEPYLRGGKVGLFGGAGVGKTVLIQELIHNIAEEHGGIS
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCEE
VFTGVGERTREGNDLYFEMKESGVLENTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVE
EEECCCCCCCCCCCEEEEECCCCCHHHHHHHEECCCCCCCCEEEEEEHHHHHHHHHHCCC
GQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSVTSI
CCEEEEEHHHHHHHHHCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
QAIYVPADDYTDPAPATTFAHLDATTNLERRLTEQGIYPAVDPLESSSSALTPEIVGDEH
EEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHCCCCH
YKVATEVQQVLQRYRELQDIISILGMDELSDEEKVVVARARRIQFFLSQNFNVAERFTGQ
HHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCC
PGSYVPVEETVKGFKAILDGKYDDYPEDAFRSVGRIEEVVEKAKKMGFAPDDQNTDADEK
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PAAQAAAN
CCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA