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The map label for this gene is ftsK [H]

Identifier: 116494423

GI number: 116494423

Start: 890986

End: 893307

Strand: Direct

Name: ftsK [H]

Synonym: LSEI_0916

Alternate gene names: 116494423

Gene position: 890986-893307 (Clockwise)

Preceding gene: 116494422

Following gene: 116494424

Centisome position: 30.77

GC content: 48.97

Gene sequence:

>2322_bases
ATGGCACAGAAACGCAGCGGACGCAAAAGCCCGCGCAGAAAACGACCTACCAAACAACAACAGCACACCCTTAGTTGGGT
CGGTGCGTTATTTGTGGTGTTCGCCAGCTTGGCATTTTTCCGGTTAGGCATTGTCGGAACCGTGTTTGCTAATGTTTTCC
GATTGGTTGTTGGTGATAGCTTTCTAGTTGTCAGCGCAGGGATGATCCTGATGGGGATTTGGTTTCTCTTCGCAGATCGA
TTGCCGAAATTGGCACGGCATGTGTGGGTTGGCCTCGCAATTATCTTAATTTGTGCCTTGGTACTGTTAAGCGCAGGCAC
CATGACCACATTGAATGTGCACAGTCATTATTTGTTGGCGACCTGGCGCCTACTTCAAAATGATTTCGGCTTAATGACGA
CGGCCTCTAGTGTTGGCGGGGGATTGATCGGGGCGGGTTTGTATGCGTTACTTGCCCCTTTACTAAGCAGCATCGGTGCA
ACGATTCTTGCATGGCTAGGCATTGTTGTTGGCACATTAGCTTTTCTAGGTGTGGGTGCGAATCAGGTTTTTAATTGGTT
GCAGCGGTGTGGGCAAGCTTGTAAACATGGCGTGATGCAGGTACAAGCAGCCGTGGCGGCTATGAAAAAAGAGCGCGCGC
AAAAAGCGGCTGCCCAGCAGAAAAAAACCGTTTCTGCGAAGCCACAGACAACTACGCCGGTCACCGAAAACGAAGCACCC
AGTGAAACACCTGATCACCAGGATGATTTCACGATTAACGGGCCGGCACCGGTTCACGAATCGACGCAACCGGCTCCCTT
GCCACGCACAGAACCTAAGCCGCAGTCAGTTACGACTGCGCCACAACCTGAGCCTAGTGAAGCGGCATCTGGACTTGATG
CAGACGATCCTTCCACGAATTATCAGTTGCCCGATCTTGACATGCTGACAACGATTCCGCCAGTTGATCAAAGTGCTGAA
TACAAGGCGATCAAAACAAATCGGGTTAAACTAAAAGAAACCTTTGAAAGTTTTGGGGTTCATGTTGCGGTTAAAAGTGC
CACACTTGGACCATCGATTACCCAATACGAGATTCAGCCAGCGGTCGGCGTTAAGGTTTCAAAGATTGTCAATCTTTCGG
ACGATCTGGCCTTAGCTTTGGCAGCAAAGGATATCCGAATCGAAGCACCGATTCCTGGTAAATCATTGATTGGGATTGAA
GTGCCAAATCAACACATTGCAACGGTCGGCTTCAAACAAGTCATGGCAGAAACGCCGAAGTCGCCTGATCGCCCATTAGT
CTTACCATTGGGTCGCGATGTGAACGGCAAAGTCGTGACTTTTGATTTGACAAAAATGCCGCACTTGCTGATTGCCGGCG
CCACCGGTTCTGGTAAATCAGTCATGATCAACGTCATTTTAACTAGCATTTTAATGCGAACGAAGCCAAGTGATGTTCGC
TTAATGTTGATAGATCCTAAACGGGTTGAATTGTCGGTATACAACGGCGTGCCGCATCTATTAACGCCGGTTGTGACAGA
AGCTAAACGGGCGCCAAGTGCGCTGAACAAGATTTTAACGGCCATGGATGAGCGGTATCAACGTTTTGCTGCGGCTGGCG
TGCGGAATATGACCGAATTTAATCAAAAGGTGGCGGCTGATCCGACAAGCGGCCAACAAAAGATGCCGTATATTGTCGTG
ATCATAGATGAGTTGAGTGATTTGATGATGGTGGCAGGTAACGAAATTGAAACTGCCATCGTCCGCTTGGCTCAAATGGC
ACGAGCAGCTGGTATTCACGTCATCATTGCGACACAACGGCCGTCTGTGGATGTCATCACTGGGCTAATGAAAGCGAATA
TTCCCTCGCGGATTGCTTTTGCAACGTCTAGTGGCATCGATTCACGAACTATTTTAGACAGTAACGGTGCCGAAAAACTT
CTGGGTCGCGGTGACATGCTCTTTTCACCAATTGGGGCATCTAAACCGATGCGAATTCAAGGTGCCTTCATACCATCTGT
GGACGTTGAGCGAGTTGTTAAGGCAATTACTGACCAAGTTTCACCTGCATATGTGGAGAGCATGACGCCAACGGAAAATA
CGGAGGCTGAGAAACCCGGTGATTCAGAGGATGAGCTATATGATGATGCGAAGGCGTTTGTCATTTCACAGCAGAGTGCC
TCGACGTCAATGCTGCAAAGACGCTTCCGAATTGGTTACAATCGAGCAGCGCGCTTGATTGATGATCTTGAAGCCAATCA
AATTGTTGGGCCAAGTGAAGGCAGCAAACCGCGCAAAGTCTTTGTGACGCCAGAACAAGTAACGAATGGTACGCCATCAT
AA

Upstream 100 bases:

>100_bases
ACAGGCGTTGTCTTTTAGCTCAATGATCGCTGAATCATCATGGCTTTTTATTTGCGAGTTCAGCTCGTGTATAATAGGCG
GGTATGAAAGGAGCATCACG

Downstream 100 bases:

>100_bases
GGAGTTTTATGCGAAAAGAAATGAAACCGGGTGTTTGGTTGATTGTCTTGCCGACAACGCAATTTAAAACCACCCGCATC
AATGTGCAATTTTTAGCACC

Product: DNA segregation ATPase FtsK/SpoIIIE related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 773; Mature: 772

Protein sequence:

>773_residues
MAQKRSGRKSPRRKRPTKQQQHTLSWVGALFVVFASLAFFRLGIVGTVFANVFRLVVGDSFLVVSAGMILMGIWFLFADR
LPKLARHVWVGLAIILICALVLLSAGTMTTLNVHSHYLLATWRLLQNDFGLMTTASSVGGGLIGAGLYALLAPLLSSIGA
TILAWLGIVVGTLAFLGVGANQVFNWLQRCGQACKHGVMQVQAAVAAMKKERAQKAAAQQKKTVSAKPQTTTPVTENEAP
SETPDHQDDFTINGPAPVHESTQPAPLPRTEPKPQSVTTAPQPEPSEAASGLDADDPSTNYQLPDLDMLTTIPPVDQSAE
YKAIKTNRVKLKETFESFGVHVAVKSATLGPSITQYEIQPAVGVKVSKIVNLSDDLALALAAKDIRIEAPIPGKSLIGIE
VPNQHIATVGFKQVMAETPKSPDRPLVLPLGRDVNGKVVTFDLTKMPHLLIAGATGSGKSVMINVILTSILMRTKPSDVR
LMLIDPKRVELSVYNGVPHLLTPVVTEAKRAPSALNKILTAMDERYQRFAAAGVRNMTEFNQKVAADPTSGQQKMPYIVV
IIDELSDLMMVAGNEIETAIVRLAQMARAAGIHVIIATQRPSVDVITGLMKANIPSRIAFATSSGIDSRTILDSNGAEKL
LGRGDMLFSPIGASKPMRIQGAFIPSVDVERVVKAITDQVSPAYVESMTPTENTEAEKPGDSEDELYDDAKAFVISQQSA
STSMLQRRFRIGYNRAARLIDDLEANQIVGPSEGSKPRKVFVTPEQVTNGTPS

Sequences:

>Translated_773_residues
MAQKRSGRKSPRRKRPTKQQQHTLSWVGALFVVFASLAFFRLGIVGTVFANVFRLVVGDSFLVVSAGMILMGIWFLFADR
LPKLARHVWVGLAIILICALVLLSAGTMTTLNVHSHYLLATWRLLQNDFGLMTTASSVGGGLIGAGLYALLAPLLSSIGA
TILAWLGIVVGTLAFLGVGANQVFNWLQRCGQACKHGVMQVQAAVAAMKKERAQKAAAQQKKTVSAKPQTTTPVTENEAP
SETPDHQDDFTINGPAPVHESTQPAPLPRTEPKPQSVTTAPQPEPSEAASGLDADDPSTNYQLPDLDMLTTIPPVDQSAE
YKAIKTNRVKLKETFESFGVHVAVKSATLGPSITQYEIQPAVGVKVSKIVNLSDDLALALAAKDIRIEAPIPGKSLIGIE
VPNQHIATVGFKQVMAETPKSPDRPLVLPLGRDVNGKVVTFDLTKMPHLLIAGATGSGKSVMINVILTSILMRTKPSDVR
LMLIDPKRVELSVYNGVPHLLTPVVTEAKRAPSALNKILTAMDERYQRFAAAGVRNMTEFNQKVAADPTSGQQKMPYIVV
IIDELSDLMMVAGNEIETAIVRLAQMARAAGIHVIIATQRPSVDVITGLMKANIPSRIAFATSSGIDSRTILDSNGAEKL
LGRGDMLFSPIGASKPMRIQGAFIPSVDVERVVKAITDQVSPAYVESMTPTENTEAEKPGDSEDELYDDAKAFVISQQSA
STSMLQRRFRIGYNRAARLIDDLEANQIVGPSEGSKPRKVFVTPEQVTNGTPS
>Mature_772_residues
AQKRSGRKSPRRKRPTKQQQHTLSWVGALFVVFASLAFFRLGIVGTVFANVFRLVVGDSFLVVSAGMILMGIWFLFADRL
PKLARHVWVGLAIILICALVLLSAGTMTTLNVHSHYLLATWRLLQNDFGLMTTASSVGGGLIGAGLYALLAPLLSSIGAT
ILAWLGIVVGTLAFLGVGANQVFNWLQRCGQACKHGVMQVQAAVAAMKKERAQKAAAQQKKTVSAKPQTTTPVTENEAPS
ETPDHQDDFTINGPAPVHESTQPAPLPRTEPKPQSVTTAPQPEPSEAASGLDADDPSTNYQLPDLDMLTTIPPVDQSAEY
KAIKTNRVKLKETFESFGVHVAVKSATLGPSITQYEIQPAVGVKVSKIVNLSDDLALALAAKDIRIEAPIPGKSLIGIEV
PNQHIATVGFKQVMAETPKSPDRPLVLPLGRDVNGKVVTFDLTKMPHLLIAGATGSGKSVMINVILTSILMRTKPSDVRL
MLIDPKRVELSVYNGVPHLLTPVVTEAKRAPSALNKILTAMDERYQRFAAAGVRNMTEFNQKVAADPTSGQQKMPYIVVI
IDELSDLMMVAGNEIETAIVRLAQMARAAGIHVIIATQRPSVDVITGLMKANIPSRIAFATSSGIDSRTILDSNGAEKLL
GRGDMLFSPIGASKPMRIQGAFIPSVDVERVVKAITDQVSPAYVESMTPTENTEAEKPGDSEDELYDDAKAFVISQQSAS
TSMLQRRFRIGYNRAARLIDDLEANQIVGPSEGSKPRKVFVTPEQVTNGTPS

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=492, Percent_Identity=45.3252032520325, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 83216; Mature: 83085

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKRSGRKSPRRKRPTKQQQHTLSWVGALFVVFASLAFFRLGIVGTVFANVFRLVVGDS
CCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FLVVSAGMILMGIWFLFADRLPKLARHVWVGLAIILICALVLLSAGTMTTLNVHSHYLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
TWRLLQNDFGLMTTASSVGGGLIGAGLYALLAPLLSSIGATILAWLGIVVGTLAFLGVGA
HHHHHHCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
NQVFNWLQRCGQACKHGVMQVQAAVAAMKKERAQKAAAQQKKTVSAKPQTTTPVTENEAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SETPDHQDDFTINGPAPVHESTQPAPLPRTEPKPQSVTTAPQPEPSEAASGLDADDPSTN
CCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCC
YQLPDLDMLTTIPPVDQSAEYKAIKTNRVKLKETFESFGVHVAVKSATLGPSITQYEIQP
CCCCCCHHHHCCCCCCCCCCCEEHHCCCHHHHHHHHHCCEEEEEECCCCCCCCEEEEECC
AVGVKVSKIVNLSDDLALALAAKDIRIEAPIPGKSLIGIEVPNQHIATVGFKQVMAETPK
CCCCCHHHHCCCCCCCEEEEEEECEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
SPDRPLVLPLGRDVNGKVVTFDLTKMPHLLIAGATGSGKSVMINVILTSILMRTKPSDVR
CCCCCEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEE
LMLIDPKRVELSVYNGVPHLLTPVVTEAKRAPSALNKILTAMDERYQRFAAAGVRNMTEF
EEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQKVAADPTSGQQKMPYIVVIIDELSDLMMVAGNEIETAIVRLAQMARAAGIHVIIATQR
HHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEECC
PSVDVITGLMKANIPSRIAFATSSGIDSRTILDSNGAEKLLGRGDMLFSPIGASKPMRIQ
CCHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCHHHHHCCCCEEECCCCCCCCEEEE
GAFIPSVDVERVVKAITDQVSPAYVESMTPTENTEAEKPGDSEDELYDDAKAFVISQQSA
ECCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCH
STSMLQRRFRIGYNRAARLIDDLEANQIVGPSEGSKPRKVFVTPEQVTNGTPS
HHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECHHHHCCCCCC
>Mature Secondary Structure 
AQKRSGRKSPRRKRPTKQQQHTLSWVGALFVVFASLAFFRLGIVGTVFANVFRLVVGDS
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FLVVSAGMILMGIWFLFADRLPKLARHVWVGLAIILICALVLLSAGTMTTLNVHSHYLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
TWRLLQNDFGLMTTASSVGGGLIGAGLYALLAPLLSSIGATILAWLGIVVGTLAFLGVGA
HHHHHHCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
NQVFNWLQRCGQACKHGVMQVQAAVAAMKKERAQKAAAQQKKTVSAKPQTTTPVTENEAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SETPDHQDDFTINGPAPVHESTQPAPLPRTEPKPQSVTTAPQPEPSEAASGLDADDPSTN
CCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCC
YQLPDLDMLTTIPPVDQSAEYKAIKTNRVKLKETFESFGVHVAVKSATLGPSITQYEIQP
CCCCCCHHHHCCCCCCCCCCCEEHHCCCHHHHHHHHHCCEEEEEECCCCCCCCEEEEECC
AVGVKVSKIVNLSDDLALALAAKDIRIEAPIPGKSLIGIEVPNQHIATVGFKQVMAETPK
CCCCCHHHHCCCCCCCEEEEEEECEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHHCCC
SPDRPLVLPLGRDVNGKVVTFDLTKMPHLLIAGATGSGKSVMINVILTSILMRTKPSDVR
CCCCCEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEE
LMLIDPKRVELSVYNGVPHLLTPVVTEAKRAPSALNKILTAMDERYQRFAAAGVRNMTEF
EEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NQKVAADPTSGQQKMPYIVVIIDELSDLMMVAGNEIETAIVRLAQMARAAGIHVIIATQR
HHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEEEEEECC
PSVDVITGLMKANIPSRIAFATSSGIDSRTILDSNGAEKLLGRGDMLFSPIGASKPMRIQ
CCHHHHHHHHHCCCCCCEEEEECCCCCCCEEECCCCHHHHHCCCCEEECCCCCCCCEEEE
GAFIPSVDVERVVKAITDQVSPAYVESMTPTENTEAEKPGDSEDELYDDAKAFVISQQSA
ECCCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCH
STSMLQRRFRIGYNRAARLIDDLEANQIVGPSEGSKPRKVFVTPEQVTNGTPS
HHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]