Click here to switch to the map view.

The map label for this gene is pimB [H]

Identifier: 116494376

GI number: 116494376

Start: 836679

End: 837887

Strand: Direct

Name: pimB [H]

Synonym: LSEI_0861

Alternate gene names: 116494376

Gene position: 836679-837887 (Clockwise)

Preceding gene: 116494374

Following gene: 116494377

Centisome position: 28.9

GC content: 46.9

Gene sequence:

>1209_bases
GTGAATATCGGGATTTTTACAGATAGCTACTTTCCACAAGTCAGTGGCGTCGCGACGTCCATCAAGACCTTGAAGGACGA
TCTGGAGCGTAAGGGCCATCAGGTTTATATTTTTACAACGACTGATCCGCATGTGCCGGACGACGCCGTTGAACCTAATT
TATTCCGATTTACCAGTGTACCGTTTGTCTCATTCACGGATCGGCGAATTGCGGTTCGTGGGCTTTTTCATGCTTACGCA
GTGGCGAAGGAATTGAACTTGGACATTGTTCATACACAAACTGAATTTTCGATGGGGTATATCGGCAAATTTGTCGCCAA
GCAGTTGAAAATTCCGACAATCCATACTTATCACACTATGTATGAGGATTATCTGCATTATGTCCTGAATGGTCATTTGC
TGAAGCCTTATCATGTGAAGCAGTTTACGCGGGCGTTTCTTTATCATGTCAGTGGCGTTGTTGCGCCTTCTGAACGCGTT
TATGATACGCTGCGGCGATATGGCGTCAAAACTGAGATCAAAATCATTCCAACTGGGGTTGATTTGACTCAGTTTGCCCA
GCAAAAAGATCCGCATTTACGTGACAAGCTCGGGTTGGCACATGTCCCGGTTTTGGTCTCACTCAGTCGGGTCGCGTATG
AAAAGCGAATTGATAAGGTGATCAGTGCCATGCCTAAAATTCTGGAACAGGTGCCCCAAGCGGTGCTGTTAATTGTTGGC
GATGGGCCTGCGCGTGAAGACTTAGAGGCGCAAGTCGCTGAGCTGGGTCTCAAGGAGCATGTCCGATTCACCGGTGAAAT
TGACCATGATGATGTTGGTGACTATTACCGGGTTGGCGATGTGTTTGTATCGGCAAGTGACTCCGAGTCACAGGGGTTAA
CTTATATCGAAGCGATGGCGGCGGATCGCAAAGTGGTTGCCTTGACAGGGGATTATACGGATCAACTTTTGGATGATCCG
GCGTTAGGGACAACATTTTCAACTGAGACTGAAATGGTGCATCAGGTCGTGAATTACTTGAAACATCCAAATGCTTACGA
TGATGCTAAGCCGCGTCAAGAAAAGTTAGCGGCAATTTCTGCAGATCGATTTGGCGATCGGGTTTTGGATTTCTATCAAG
ACATTTTGTCACACTATTCGCCTAATGAGGCCGATGAAGCTGCACCATGGACCGATGAAGATTCCAGTAAACGGACCATG
AAAGGTTAA

Upstream 100 bases:

>100_bases
GCGACAAGGTAAGATAATTTTAAAGGTTTGAGGGAAAATTGCATTTAGCTATGCCTATCTTTATACTTATACTAAACAAA
TGACGTCTGGAGGGGATTAG

Downstream 100 bases:

>100_bases
ATATGATTGTTATTAATATGTTTTCCTCTGCCAATAAGGTTGCAGGACAAGGAGTTGGCGCAGTCTACACAGAACTGATG
GGCTTGCTGAAACACGATTT

Product: glycosyltransferase

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MNIGIFTDSYFPQVSGVATSIKTLKDDLERKGHQVYIFTTTDPHVPDDAVEPNLFRFTSVPFVSFTDRRIAVRGLFHAYA
VAKELNLDIVHTQTEFSMGYIGKFVAKQLKIPTIHTYHTMYEDYLHYVLNGHLLKPYHVKQFTRAFLYHVSGVVAPSERV
YDTLRRYGVKTEIKIIPTGVDLTQFAQQKDPHLRDKLGLAHVPVLVSLSRVAYEKRIDKVISAMPKILEQVPQAVLLIVG
DGPAREDLEAQVAELGLKEHVRFTGEIDHDDVGDYYRVGDVFVSASDSESQGLTYIEAMAADRKVVALTGDYTDQLLDDP
ALGTTFSTETEMVHQVVNYLKHPNAYDDAKPRQEKLAAISADRFGDRVLDFYQDILSHYSPNEADEAAPWTDEDSSKRTM
KG

Sequences:

>Translated_402_residues
MNIGIFTDSYFPQVSGVATSIKTLKDDLERKGHQVYIFTTTDPHVPDDAVEPNLFRFTSVPFVSFTDRRIAVRGLFHAYA
VAKELNLDIVHTQTEFSMGYIGKFVAKQLKIPTIHTYHTMYEDYLHYVLNGHLLKPYHVKQFTRAFLYHVSGVVAPSERV
YDTLRRYGVKTEIKIIPTGVDLTQFAQQKDPHLRDKLGLAHVPVLVSLSRVAYEKRIDKVISAMPKILEQVPQAVLLIVG
DGPAREDLEAQVAELGLKEHVRFTGEIDHDDVGDYYRVGDVFVSASDSESQGLTYIEAMAADRKVVALTGDYTDQLLDDP
ALGTTFSTETEMVHQVVNYLKHPNAYDDAKPRQEKLAAISADRFGDRVLDFYQDILSHYSPNEADEAAPWTDEDSSKRTM
KG
>Mature_402_residues
MNIGIFTDSYFPQVSGVATSIKTLKDDLERKGHQVYIFTTTDPHVPDDAVEPNLFRFTSVPFVSFTDRRIAVRGLFHAYA
VAKELNLDIVHTQTEFSMGYIGKFVAKQLKIPTIHTYHTMYEDYLHYVLNGHLLKPYHVKQFTRAFLYHVSGVVAPSERV
YDTLRRYGVKTEIKIIPTGVDLTQFAQQKDPHLRDKLGLAHVPVLVSLSRVAYEKRIDKVISAMPKILEQVPQAVLLIVG
DGPAREDLEAQVAELGLKEHVRFTGEIDHDDVGDYYRVGDVFVSASDSESQGLTYIEAMAADRKVVALTGDYTDQLLDDP
ALGTTFSTETEMVHQVVNYLKHPNAYDDAKPRQEKLAAISADRFGDRVLDFYQDILSHYSPNEADEAAPWTDEDSSKRTM
KG

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose resid

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=314, Percent_Identity=26.1146496815287, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17532709, Length=311, Percent_Identity=21.2218649517685, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI9755344, Length=328, Percent_Identity=25, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654571, Length=312, Percent_Identity=24.0384615384615, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 45375; Mature: 45375

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGIFTDSYFPQVSGVATSIKTLKDDLERKGHQVYIFTTTDPHVPDDAVEPNLFRFTSV
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEECC
PFVSFTDRRIAVRGLFHAYAVAKELNLDIVHTQTEFSMGYIGKFVAKQLKIPTIHTYHTM
CEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHCCCEEHHHHHH
YEDYLHYVLNGHLLKPYHVKQFTRAFLYHVSGVVAPSERVYDTLRRYGVKTEIKIIPTGV
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCC
DLTQFAQQKDPHLRDKLGLAHVPVLVSLSRVAYEKRIDKVISAMPKILEQVPQAVLLIVG
CHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
DGPAREDLEAQVAELGLKEHVRFTGEIDHDDVGDYYRVGDVFVSASDSESQGLTYIEAMA
CCCCCHHHHHHHHHCCHHHHHEECCCCCCCCCCCCEEECEEEEECCCCCCCCCHHHHHHH
ADRKVVALTGDYTDQLLDDPALGTTFSTETEMVHQVVNYLKHPNAYDDAKPRQEKLAAIS
CCCEEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
ADRFGDRVLDFYQDILSHYSPNEADEAAPWTDEDSSKRTMKG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNIGIFTDSYFPQVSGVATSIKTLKDDLERKGHQVYIFTTTDPHVPDDAVEPNLFRFTSV
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEEEECC
PFVSFTDRRIAVRGLFHAYAVAKELNLDIVHTQTEFSMGYIGKFVAKQLKIPTIHTYHTM
CEEEECCCHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHCCCEEHHHHHH
YEDYLHYVLNGHLLKPYHVKQFTRAFLYHVSGVVAPSERVYDTLRRYGVKTEIKIIPTGV
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCC
DLTQFAQQKDPHLRDKLGLAHVPVLVSLSRVAYEKRIDKVISAMPKILEQVPQAVLLIVG
CHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
DGPAREDLEAQVAELGLKEHVRFTGEIDHDDVGDYYRVGDVFVSASDSESQGLTYIEAMA
CCCCCHHHHHHHHHCCHHHHHEECCCCCCCCCCCCEEECEEEEECCCCCCCCCHHHHHHH
ADRKVVALTGDYTDQLLDDPALGTTFSTETEMVHQVVNYLKHPNAYDDAKPRQEKLAAIS
CCCEEEEEECCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
ADRFGDRVLDFYQDILSHYSPNEADEAAPWTDEDSSKRTMKG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA