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The map label for this gene is rbsR [H]

Identifier: 116493935

GI number: 116493935

Start: 368214

End: 369263

Strand: Direct

Name: rbsR [H]

Synonym: LSEI_0368

Alternate gene names: 116493935

Gene position: 368214-369263 (Clockwise)

Preceding gene: 116493929

Following gene: 116493936

Centisome position: 12.72

GC content: 43.05

Gene sequence:

>1050_bases
TTGGTGATTATTGTGGCAAACAAGAAAAATGCCTCAATCAAAGACGTGGCTCGATTAAGCGGCGTTTCGGTTGCAACGGT
TTCTAGAATCATGAATGACAGTGGCCGATATTCTCAAGCTACTCGTGATAAAGTTCTTCGAGTCATTGAAGAGATTGGTT
ACGAACGTAATTCGTTGGCGACAAGCTTGCGACTCAACAAATCTAATATGATTGGGATTTTGGTTCCCAATATTGCAAAT
GAATTTTATGCGTCTGTTCTAAAAAAAGCTGAGCAAGCACTCTTTAAATTGGGCTATTCAACGATTATTTGTAATACGGA
ACGAAGTATCGAAAGGGAAACTGCCTATTATCGAATGTTGATTGAACATCGTGTAGACGGTCTCATTTCAGTATCCAGTG
CCAGCAATCAAATGCCGCTTTCAACGAAGTACGCAATTCCAATCGTCTTTATTGATCGGGATCCGCATTCTGATTCTGAG
ATGATTGTCACAACTGATCATTATGCCGCTGGTAAAGACCTTACACATTTACTCCTAAGTCAAGCCGACAATTTATGCCT
TGTCATGACCAAGTCGCGGCCATCCTCAACAATGGATCGGGTTCAGGCTTTCAAGGATGAGCTGCTAAGTAGGGGAATAA
GTTCAGAAGGTAACATTTTGGCACTAAACACAACGTCTGATAAGTTTCTGCAACGGCATCCCGACCTAAAGAACTTTATT
CAGAATGAACACCAGCAAGGCAAACGCCTTGGCGTATTTGCGATCAATGATAATGTTGCTTATATGGTTCTTAAAGTCGC
AGAGGAACTGGACCTACGAGTGCCAGAGGATCTGATTGTGACGGGGTTTGATGGCATGTCGATTGCGGCTATTTCTCGAC
CAACGATCACCACGATTGTTCAAGATTCCACTACAATTGCTAACAAAGCTAGCCAGTTGTTGGTTGAAACGATTAAGAAG
GGTGTGGATCAGGCTGACAAGCATGGTACGGTGCATGTTCCATATCGCCTTGCGCAGAGGAAAAGCACATTACCGGAAGA
TCAAGTGTGA

Upstream 100 bases:

>100_bases
ATTGCTAAGTTTATTCAAATTTGGTATTATTGTGTAAACGTTTTCGCATCTTTCAGAATCTATTAAACAACGTGTCCTGT
GAAAAGTCAAACAAAAAAAC

Downstream 100 bases:

>100_bases
CAAGATTAAAACTGTTATGCCGTAGTACTCAACGTTTAAGGTAAATAAGAGGGACAGATGAGAAGTTTTAGACTTCTTGA
CTGTCCCTTTTGTTTTTGGC

Product: sugar metabolism regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MVIIVANKKNASIKDVARLSGVSVATVSRIMNDSGRYSQATRDKVLRVIEEIGYERNSLATSLRLNKSNMIGILVPNIAN
EFYASVLKKAEQALFKLGYSTIICNTERSIERETAYYRMLIEHRVDGLISVSSASNQMPLSTKYAIPIVFIDRDPHSDSE
MIVTTDHYAAGKDLTHLLLSQADNLCLVMTKSRPSSTMDRVQAFKDELLSRGISSEGNILALNTTSDKFLQRHPDLKNFI
QNEHQQGKRLGVFAINDNVAYMVLKVAEELDLRVPEDLIVTGFDGMSIAAISRPTITTIVQDSTTIANKASQLLVETIKK
GVDQADKHGTVHVPYRLAQRKSTLPEDQV

Sequences:

>Translated_349_residues
MVIIVANKKNASIKDVARLSGVSVATVSRIMNDSGRYSQATRDKVLRVIEEIGYERNSLATSLRLNKSNMIGILVPNIAN
EFYASVLKKAEQALFKLGYSTIICNTERSIERETAYYRMLIEHRVDGLISVSSASNQMPLSTKYAIPIVFIDRDPHSDSE
MIVTTDHYAAGKDLTHLLLSQADNLCLVMTKSRPSSTMDRVQAFKDELLSRGISSEGNILALNTTSDKFLQRHPDLKNFI
QNEHQQGKRLGVFAINDNVAYMVLKVAEELDLRVPEDLIVTGFDGMSIAAISRPTITTIVQDSTTIANKASQLLVETIKK
GVDQADKHGTVHVPYRLAQRKSTLPEDQV
>Mature_349_residues
MVIIVANKKNASIKDVARLSGVSVATVSRIMNDSGRYSQATRDKVLRVIEEIGYERNSLATSLRLNKSNMIGILVPNIAN
EFYASVLKKAEQALFKLGYSTIICNTERSIERETAYYRMLIEHRVDGLISVSSASNQMPLSTKYAIPIVFIDRDPHSDSE
MIVTTDHYAAGKDLTHLLLSQADNLCLVMTKSRPSSTMDRVQAFKDELLSRGISSEGNILALNTTSDKFLQRHPDLKNFI
QNEHQQGKRLGVFAINDNVAYMVLKVAEELDLRVPEDLIVTGFDGMSIAAISRPTITTIVQDSTTIANKASQLLVETIKK
GVDQADKHGTVHVPYRLAQRKSTLPEDQV

Specific function: Transcriptional repressor for the ribose rbsDACBK operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=324, Percent_Identity=29.0123456790123, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1787948, Length=337, Percent_Identity=25.8160237388724, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1789202, Length=313, Percent_Identity=27.1565495207668, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1790369, Length=320, Percent_Identity=25.625, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787906, Length=228, Percent_Identity=28.9473684210526, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1790715, Length=349, Percent_Identity=25.5014326647564, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788474, Length=327, Percent_Identity=26.2996941896024, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI48994940, Length=318, Percent_Identity=22.3270440251572, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789068, Length=295, Percent_Identity=25.0847457627119, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787580, Length=316, Percent_Identity=24.6835443037975, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786540, Length=348, Percent_Identity=26.4367816091954, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786268, Length=147, Percent_Identity=29.9319727891156, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38768; Mature: 38768

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIIVANKKNASIKDVARLSGVSVATVSRIMNDSGRYSQATRDKVLRVIEEIGYERNSLA
CEEEEECCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
TSLRLNKSNMIGILVPNIANEFYASVLKKAEQALFKLGYSTIICNTERSIERETAYYRML
HEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHH
IEHRVDGLISVSSASNQMPLSTKYAIPIVFIDRDPHSDSEMIVTTDHYAAGKDLTHLLLS
HHHHHCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHH
QADNLCLVMTKSRPSSTMDRVQAFKDELLSRGISSEGNILALNTTSDKFLQRHPDLKNFI
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCHHHHH
QNEHQQGKRLGVFAINDNVAYMVLKVAEELDLRVPEDLIVTGFDGMSIAAISRPTITTIV
HHHHHCCCEEEEEEECCCCEEHHHHHHHHHCCCCCCCEEEECCCCCEEEEECCCCEEEEE
QDSTTIANKASQLLVETIKKGVDQADKHGTVHVPYRLAQRKSTLPEDQV
CCCHHHHHHHHHHHHHHHHHHHCHHHCCCEEECCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVIIVANKKNASIKDVARLSGVSVATVSRIMNDSGRYSQATRDKVLRVIEEIGYERNSLA
CEEEEECCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHH
TSLRLNKSNMIGILVPNIANEFYASVLKKAEQALFKLGYSTIICNTERSIERETAYYRML
HEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHH
IEHRVDGLISVSSASNQMPLSTKYAIPIVFIDRDPHSDSEMIVTTDHYAAGKDLTHLLLS
HHHHHCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHH
QADNLCLVMTKSRPSSTMDRVQAFKDELLSRGISSEGNILALNTTSDKFLQRHPDLKNFI
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCHHHHH
QNEHQQGKRLGVFAINDNVAYMVLKVAEELDLRVPEDLIVTGFDGMSIAAISRPTITTIV
HHHHHCCCEEEEEEECCCCEEHHHHHHHHHCCCCCCCEEEECCCCCEEEEECCCCEEEEE
QDSTTIANKASQLLVETIKKGVDQADKHGTVHVPYRLAQRKSTLPEDQV
CCCHHHHHHHHHHHHHHHHHHHCHHHCCCEEECCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]