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The map label for this gene is ycaM [H]

Identifier: 116493871

GI number: 116493871

Start: 304003

End: 305451

Strand: Direct

Name: ycaM [H]

Synonym: LSEI_0303

Alternate gene names: 116493871

Gene position: 304003-305451 (Clockwise)

Preceding gene: 116493870

Following gene: 116493873

Centisome position: 10.5

GC content: 47.76

Gene sequence:

>1449_bases
GTGCAAGAAGAAGAACTGACGCCCCGGCGGTATATGAGCTGGCCAGTCTTAAGCTTACTTGTTTTTATTACGGTCATTGG
TTTTGAAAATATTTTTTATCCTTTTCAGAACCAAGGGCTTTCCGTTGTTGTTAACTGGGTCATCCTGTTGGTGATTTATA
TCGTGCCGTACGCCTTGATTTCGGCACAATTAGGGACGACTTTTACCCGGGCTGATGAAGGCGGTGGCTTGGCGACTTGG
ATGCGCCGCACGCTAGGGGACACTTGGGGATACTGGACAAGCTGGATTTATTGGGCTCAGACCCTGCCATATTTAGTCGA
TGTTTCCAACGCTGTCATCGTGGCGCTTTCCTGGATGATTCTGGGTGATAACAGTTTGGGTAAACGAATGTCGAATCTGA
CCTTTGGCCTGCTGACTTTTGCTATTATTCTTTTATTTATTGTGTTAGAGAACCTGTTCTCCCGATCACTTGAAGTCATG
TCGCTAATTGGCGGTGCGGCGATGTTTTTGATGGCGGTTTTATTCGTTGTCTTGACGGCGGCCGGTTTGGCCAAAGGCAT
GCATTCGGCAACAAACTTTAGTTGGGCCGCGTTCAAGCCACATTTTTCGCTGCATTACTTTGCCACGACCGGACTCTTGA
TTTTTGCGACATCAGGGGCGGAACTTGGCGCCACTTATGTTGCTCAGTTGCGCAACCCGAAAAAAGAGTTTCCTAAAGCC
ATGTGGGCTCTGGCGCTCATGACCGGTTTTTTGGTGATTTTTGGATCGCTGGCATTAGGCGTTTGGTTCAATGCCAACCA
TCTGCCAGATGATCTCAAAATGAATGGCGCTTATTATGCCTTTTCCATGCTTGGTCAGGCGTGGGGATGGGGCAAAGTGC
TGATGTATTTGTTTGCCATCACGCAATTACTCTTCATGCTCGCCCAGCTAGCGGTGTTGATTGATGCTTCCAGCCGGGTA
TTGTCAGCCGACACCGCCATGCGGTTCATGCCTAAATGGTTGTTGCAGAAAAACAAGCAAGGTCGGCCAATCCATAGTTA
TATTTTTACCGCCTCACTTTGCCTGTTCTTGCTGTTGCTGTCAGGGACGCTGCCGAATATTAATGCCATCTTCAACTGGT
TACTGAATTTGAATGGTATTGTATCGCCATACAAAACGGCGCTTGTCTTTGTGGCTTTCTTGGCGTTGCGGGCGCAAGCA
GACAAGTTCACTTCCGGCTATACCTTCATCAAAAGTAAGGCCGGTGCTTATCTAGTTGGCGGTTGGTGTTTTGTCTTCAC
CTTTATCTGTGCGACGCTTGGTTTCTTACCACAGGAAGTTGTTTTCGGAACCAATGGCTGGACCCATCAACTGGTGATGA
ATATCATCTCCGTGATGGTACTCTTCGGTTTTGGCTTCATCATGCCGCTGTTAGCAAGGCGTGATGTTAAAAAAGAACGG
CTCATGTAA

Upstream 100 bases:

>100_bases
CTAGCCTGTCATCAAGAGGCTATCAAACCAGCCTGCATCCCGATATGTGACCAGTACCGAGCTACAGGCGCTCTTAGTTT
GTATTTGGAGGCTTTGAATT

Downstream 100 bases:

>100_bases
GCCAATCTAAATGATGAGGCGTCACCACGCTGTTGCGGGTGATGTTTCATCATTTTTGAATACGCATTCAAAATTTAATG
ACATTTTTGTAGTCAAAGGA

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MQEEELTPRRYMSWPVLSLLVFITVIGFENIFYPFQNQGLSVVVNWVILLVIYIVPYALISAQLGTTFTRADEGGGLATW
MRRTLGDTWGYWTSWIYWAQTLPYLVDVSNAVIVALSWMILGDNSLGKRMSNLTFGLLTFAIILLFIVLENLFSRSLEVM
SLIGGAAMFLMAVLFVVLTAAGLAKGMHSATNFSWAAFKPHFSLHYFATTGLLIFATSGAELGATYVAQLRNPKKEFPKA
MWALALMTGFLVIFGSLALGVWFNANHLPDDLKMNGAYYAFSMLGQAWGWGKVLMYLFAITQLLFMLAQLAVLIDASSRV
LSADTAMRFMPKWLLQKNKQGRPIHSYIFTASLCLFLLLLSGTLPNINAIFNWLLNLNGIVSPYKTALVFVAFLALRAQA
DKFTSGYTFIKSKAGAYLVGGWCFVFTFICATLGFLPQEVVFGTNGWTHQLVMNIISVMVLFGFGFIMPLLARRDVKKER
LM

Sequences:

>Translated_482_residues
MQEEELTPRRYMSWPVLSLLVFITVIGFENIFYPFQNQGLSVVVNWVILLVIYIVPYALISAQLGTTFTRADEGGGLATW
MRRTLGDTWGYWTSWIYWAQTLPYLVDVSNAVIVALSWMILGDNSLGKRMSNLTFGLLTFAIILLFIVLENLFSRSLEVM
SLIGGAAMFLMAVLFVVLTAAGLAKGMHSATNFSWAAFKPHFSLHYFATTGLLIFATSGAELGATYVAQLRNPKKEFPKA
MWALALMTGFLVIFGSLALGVWFNANHLPDDLKMNGAYYAFSMLGQAWGWGKVLMYLFAITQLLFMLAQLAVLIDASSRV
LSADTAMRFMPKWLLQKNKQGRPIHSYIFTASLCLFLLLLSGTLPNINAIFNWLLNLNGIVSPYKTALVFVAFLALRAQA
DKFTSGYTFIKSKAGAYLVGGWCFVFTFICATLGFLPQEVVFGTNGWTHQLVMNIISVMVLFGFGFIMPLLARRDVKKER
LM
>Mature_482_residues
MQEEELTPRRYMSWPVLSLLVFITVIGFENIFYPFQNQGLSVVVNWVILLVIYIVPYALISAQLGTTFTRADEGGGLATW
MRRTLGDTWGYWTSWIYWAQTLPYLVDVSNAVIVALSWMILGDNSLGKRMSNLTFGLLTFAIILLFIVLENLFSRSLEVM
SLIGGAAMFLMAVLFVVLTAAGLAKGMHSATNFSWAAFKPHFSLHYFATTGLLIFATSGAELGATYVAQLRNPKKEFPKA
MWALALMTGFLVIFGSLALGVWFNANHLPDDLKMNGAYYAFSMLGQAWGWGKVLMYLFAITQLLFMLAQLAVLIDASSRV
LSADTAMRFMPKWLLQKNKQGRPIHSYIFTASLCLFLLLLSGTLPNINAIFNWLLNLNGIVSPYKTALVFVAFLALRAQA
DKFTSGYTFIKSKAGAYLVGGWCFVFTFICATLGFLPQEVVFGTNGWTHQLVMNIISVMVLFGFGFIMPLLARRDVKKER
LM

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081798, Length=473, Percent_Identity=39.5348837209302, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI48994921, Length=450, Percent_Identity=20.4444444444444, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082380, Length=241, Percent_Identity=26.1410788381743, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53870; Mature: 53870

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEEELTPRRYMSWPVLSLLVFITVIGFENIFYPFQNQGLSVVVNWVILLVIYIVPYALI
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SAQLGTTFTRADEGGGLATWMRRTLGDTWGYWTSWIYWAQTLPYLVDVSNAVIVALSWMI
HHHHCCHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGDNSLGKRMSNLTFGLLTFAIILLFIVLENLFSRSLEVMSLIGGAAMFLMAVLFVVLTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLAKGMHSATNFSWAAFKPHFSLHYFATTGLLIFATSGAELGATYVAQLRNPKKEFPKA
HHHHHHHHHCCCCCEEEECCCCEEEHHHHCCEEEEEECCCHHHHHHHHHHCCCHHHHHHH
MWALALMTGFLVIFGSLALGVWFNANHLPDDLKMNGAYYAFSMLGQAWGWGKVLMYLFAI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHCCCHHHHHHHHHHH
TQLLFMLAQLAVLIDASSRVLSADTAMRFMPKWLLQKNKQGRPIHSYIFTASLCLFLLLL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SGTLPNINAIFNWLLNLNGIVSPYKTALVFVAFLALRAQADKFTSGYTFIKSKAGAYLVG
HCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEH
GWCFVFTFICATLGFLPQEVVFGTNGWTHQLVMNIISVMVLFGFGFIMPLLARRDVKKER
HHHHHHHHHHHHHCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LM
CC
>Mature Secondary Structure
MQEEELTPRRYMSWPVLSLLVFITVIGFENIFYPFQNQGLSVVVNWVILLVIYIVPYALI
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SAQLGTTFTRADEGGGLATWMRRTLGDTWGYWTSWIYWAQTLPYLVDVSNAVIVALSWMI
HHHHCCHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGDNSLGKRMSNLTFGLLTFAIILLFIVLENLFSRSLEVMSLIGGAAMFLMAVLFVVLTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLAKGMHSATNFSWAAFKPHFSLHYFATTGLLIFATSGAELGATYVAQLRNPKKEFPKA
HHHHHHHHHCCCCCEEEECCCCEEEHHHHCCEEEEEECCCHHHHHHHHHHCCCHHHHHHH
MWALALMTGFLVIFGSLALGVWFNANHLPDDLKMNGAYYAFSMLGQAWGWGKVLMYLFAI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHCCCHHHHHHHHHHH
TQLLFMLAQLAVLIDASSRVLSADTAMRFMPKWLLQKNKQGRPIHSYIFTASLCLFLLLL
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
SGTLPNINAIFNWLLNLNGIVSPYKTALVFVAFLALRAQADKFTSGYTFIKSKAGAYLVG
HCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEH
GWCFVFTFICATLGFLPQEVVFGTNGWTHQLVMNIISVMVLFGFGFIMPLLARRDVKKER
HHHHHHHHHHHHHCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LM
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]