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The map label for this gene is ykoE [H]

Identifier: 116493862

GI number: 116493862

Start: 297480

End: 298046

Strand: Direct

Name: ykoE [H]

Synonym: LSEI_0294

Alternate gene names: 116493862

Gene position: 297480-298046 (Clockwise)

Preceding gene: 116493860

Following gene: 116493863

Centisome position: 10.27

GC content: 49.91

Gene sequence:

>567_bases
ATGGATAAATGGTCTTTGCGCGATGTGGTTTTGCTGGCGTTTTTAGCCTTCCTCTTCGGCGGTGTTTTCATGGGTGCCGA
TGCAATTTATGCCGTTGTAGCAGCTGCTTTGACACCGCTGGGTTATGCACCGTTTGCCAATGAATTGTTGTTTGGCATGT
GGGTGATGGCGGCGCCGATGACGACGATGCTGTTGCGAAAAAAAGGCAGTTCAATTTTAGGCGAATGTTTCGCTGCTTTA
GCGGAGATGCTTTACGGGTCGTACTTTGGCCCAGCAGTCTTGCTTTCTGGATTTGTTCAAGGTTTGGGCAGCGAGGCCGG
CTTTATGGTGACACGTTATCGGCGTTATGACGTCGTGAGTCTTTTGTACGCAGCGATTGGGACCACGGTGTTCAGTTTTA
CCTACGAGTATTTCAAACTTGGATACGGCGCTTACAGTCTTGGCATGATTTTGGCGCTTGTGGTGGTTCGCTTGTTGTCA
GTGATCTTTTTCGGCGTTGTGCTGGTCCAACTCGTTCTGAAACTTTATGAACAGGCGGCTGGTGCCAAGCACTTGGCTAG
CAGGTAG

Upstream 100 bases:

>100_bases
GGGTCCTTTTTTGAACATGAATAGGTGTTGGCGTGATTGGTAATGATTCGCGTTTTTAGCCCCCGTCTGTCTTTATTTGA
GGAAAACGGGGGTTATTTTG

Downstream 100 bases:

>100_bases
CGGCAAATGAGTATTGTGTTAAAAGCGATACGGTTTCATCGCGAGACGGATTTGTTTACGGACTTGAATTTTGAATTTCC
AACAGGAGCACTAACCGTTT

Product: ABC-type cobalt transport system, permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MDKWSLRDVVLLAFLAFLFGGVFMGADAIYAVVAAALTPLGYAPFANELLFGMWVMAAPMTTMLLRKKGSSILGECFAAL
AEMLYGSYFGPAVLLSGFVQGLGSEAGFMVTRYRRYDVVSLLYAAIGTTVFSFTYEYFKLGYGAYSLGMILALVVVRLLS
VIFFGVVLVQLVLKLYEQAAGAKHLASR

Sequences:

>Translated_188_residues
MDKWSLRDVVLLAFLAFLFGGVFMGADAIYAVVAAALTPLGYAPFANELLFGMWVMAAPMTTMLLRKKGSSILGECFAAL
AEMLYGSYFGPAVLLSGFVQGLGSEAGFMVTRYRRYDVVSLLYAAIGTTVFSFTYEYFKLGYGAYSLGMILALVVVRLLS
VIFFGVVLVQLVLKLYEQAAGAKHLASR
>Mature_188_residues
MDKWSLRDVVLLAFLAFLFGGVFMGADAIYAVVAAALTPLGYAPFANELLFGMWVMAAPMTTMLLRKKGSSILGECFAAL
AEMLYGSYFGPAVLLSGFVQGLGSEAGFMVTRYRRYDVVSLLYAAIGTTVFSFTYEYFKLGYGAYSLGMILALVVVRLLS
VIFFGVVLVQLVLKLYEQAAGAKHLASR

Specific function: Part of the ABC transporter complex ykoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Probably responsible for the translocation of the substrate across the membrane (Probable)

COG id: COG4721

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017195 [H]

Pfam domain/function: PF09819 ABC_cobalt [H]

EC number: NA

Molecular weight: Translated: 20432; Mature: 20432

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKWSLRDVVLLAFLAFLFGGVFMGADAIYAVVAAALTPLGYAPFANELLFGMWVMAAPM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TTMLLRKKGSSILGECFAALAEMLYGSYFGPAVLLSGFVQGLGSEAGFMVTRYRRYDVVS
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LLYAAIGTTVFSFTYEYFKLGYGAYSLGMILALVVVRLLSVIFFGVVLVQLVLKLYEQAA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAKHLASR
CHHHHCCC
>Mature Secondary Structure
MDKWSLRDVVLLAFLAFLFGGVFMGADAIYAVVAAALTPLGYAPFANELLFGMWVMAAPM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TTMLLRKKGSSILGECFAALAEMLYGSYFGPAVLLSGFVQGLGSEAGFMVTRYRRYDVVS
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LLYAAIGTTVFSFTYEYFKLGYGAYSLGMILALVVVRLLSVIFFGVVLVQLVLKLYEQAA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAKHLASR
CHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]