Click here to switch to the map view.

The map label for this gene is supH [H]

Identifier: 116493598

GI number: 116493598

Start: 25746

End: 26552

Strand: Direct

Name: supH [H]

Synonym: LSEI_0024

Alternate gene names: 116493598

Gene position: 25746-26552 (Clockwise)

Preceding gene: 116493597

Following gene: 116493599

Centisome position: 0.89

GC content: 46.22

Gene sequence:

>807_bases
ATGCAGAATGTAAAATTAATTGCGAGTGACATGGACCAGACTTTACTGACAAGTGCAGGGACCTTGCCGCCGCATTTTGA
TCGTTATCTTCATCGCCTTGGCGAGGCTGGCATTGAGTTTGCCGTGGCTAGTGGACGGCCGCTTTATACGCTACAGGAAA
CTTTCCCACACTTTAGTGACCGAATTTCGATGGTCTGCGATAACGGCGGCCTTGTTTATTCGCACGGCCAATTAATCGGG
AAAAGCCTGATCCCTGAGGAAAAATATCGTGAGATCGTGCAATTTATCATGACGAAAACAGACGGTGTTCCTGTCCTGTG
TGCTTTGGATGCCGCGTATATTAATGCTACTGATGCCCAATATTCACCAGCTCTTTTGCCGTTTTATCACCAATTGAAAA
AGGTGCCGGATTTGTTAACGCAGTCGCTGGCAGTTGATAAGGTGACGATTTATTTTCCAAATAAAGACAGCCGCAAAAAT
TCCGAACGTTATTTCCGCCCAGTATTTGGCAAGAATTATACCGTTCAAGTCAGCGGTGAGACTTGGCTAGATATTCAGAA
CCTCGGCGTGAACAAGGGCCGCGGCATGCGAATTTTGAGTCGTCATTTTGATATTCCTACGACACAAATGATGGCGTTTG
GCGATTATGATAATGATATTCCAATGCTAGAAACGGTTGGTTACAGTTACATCATGGCCAATGCAACGCAAGGCATGGCG
CAACATGCCAAATATCGCACGCGGAGTAACGATGAATTCGGCGTCTTGCATGTGATGGATCAGGTGTTACAAGCGCAAGA
AGGCTAG

Upstream 100 bases:

>100_bases
TCTGAACAGATTGCGGCGGTGATCGAAAATGTCGTGACTAAAGGCGCACCGCATTAAATTATAGCAAGTGAAATTAGACA
AATAATATAGGGGAATTAGC

Downstream 100 bases:

>100_bases
GCTAATGGCAGTTATCTCAATACGTGTGGCAATTGGTGTATACGGCTTTTTGATGTTATTAACAGCGTGGCAAGCATGGC
AGAAAAAACAAGGGGATGTC

Product: HAD superfamily hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MQNVKLIASDMDQTLLTSAGTLPPHFDRYLHRLGEAGIEFAVASGRPLYTLQETFPHFSDRISMVCDNGGLVYSHGQLIG
KSLIPEEKYREIVQFIMTKTDGVPVLCALDAAYINATDAQYSPALLPFYHQLKKVPDLLTQSLAVDKVTIYFPNKDSRKN
SERYFRPVFGKNYTVQVSGETWLDIQNLGVNKGRGMRILSRHFDIPTTQMMAFGDYDNDIPMLETVGYSYIMANATQGMA
QHAKYRTRSNDEFGVLHVMDQVLQAQEG

Sequences:

>Translated_268_residues
MQNVKLIASDMDQTLLTSAGTLPPHFDRYLHRLGEAGIEFAVASGRPLYTLQETFPHFSDRISMVCDNGGLVYSHGQLIG
KSLIPEEKYREIVQFIMTKTDGVPVLCALDAAYINATDAQYSPALLPFYHQLKKVPDLLTQSLAVDKVTIYFPNKDSRKN
SERYFRPVFGKNYTVQVSGETWLDIQNLGVNKGRGMRILSRHFDIPTTQMMAFGDYDNDIPMLETVGYSYIMANATQGMA
QHAKYRTRSNDEFGVLHVMDQVLQAQEG
>Mature_268_residues
MQNVKLIASDMDQTLLTSAGTLPPHFDRYLHRLGEAGIEFAVASGRPLYTLQETFPHFSDRISMVCDNGGLVYSHGQLIG
KSLIPEEKYREIVQFIMTKTDGVPVLCALDAAYINATDAQYSPALLPFYHQLKKVPDLLTQSLAVDKVTIYFPNKDSRKN
SERYFRPVFGKNYTVQVSGETWLDIQNLGVNKGRGMRILSRHFDIPTTQMMAFGDYDNDIPMLETVGYSYIMANATQGMA
QHAKYRTRSNDEFGVLHVMDQVLQAQEG

Specific function: Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of fructose-1-P most efficiently, but it remains uncertain if this is the real substrate in vivo [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family. SupH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787043, Length=263, Percent_Identity=31.5589353612167, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87081790, Length=267, Percent_Identity=29.5880149812734, Blast_Score=117, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.23 [H]

Molecular weight: Translated: 30216; Mature: 30216

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNVKLIASDMDQTLLTSAGTLPPHFDRYLHRLGEAGIEFAVASGRPLYTLQETFPHFSD
CCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCEEEHHHHCCCHHH
RISMVCDNGGLVYSHGQLIGKSLIPEEKYREIVQFIMTKTDGVPVLCALDAAYINATDAQ
CEEEEECCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECHHHEECCCCC
YSPALLPFYHQLKKVPDLLTQSLAVDKVTIYFPNKDSRKNSERYFRPVFGKNYTVQVSGE
CCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHCCCCEEEEECCC
TWLDIQNLGVNKGRGMRILSRHFDIPTTQMMAFGDYDNDIPMLETVGYSYIMANATQGMA
EEEEHCCCCCCCCCCHHHHHHHCCCCHHHEEEECCCCCCCCHHHHCCCHHEEEHHHHHHH
QHAKYRTRSNDEFGVLHVMDQVLQAQEG
HHHHHHCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQNVKLIASDMDQTLLTSAGTLPPHFDRYLHRLGEAGIEFAVASGRPLYTLQETFPHFSD
CCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCEEEHHHHCCCHHH
RISMVCDNGGLVYSHGQLIGKSLIPEEKYREIVQFIMTKTDGVPVLCALDAAYINATDAQ
CEEEEECCCCEEEECHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECHHHEECCCCC
YSPALLPFYHQLKKVPDLLTQSLAVDKVTIYFPNKDSRKNSERYFRPVFGKNYTVQVSGE
CCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHCCCCEEEEECCC
TWLDIQNLGVNKGRGMRILSRHFDIPTTQMMAFGDYDNDIPMLETVGYSYIMANATQGMA
EEEEHCCCCCCCCCCHHHHHHHCCCCHHHEEEECCCCCCCCHHHHCCCHHEEEHHHHHHH
QHAKYRTRSNDEFGVLHVMDQVLQAQEG
HHHHHHCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]