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The map label for this gene is ydhC [C]

Identifier: 116493416

GI number: 116493416

Start: 1664029

End: 1665204

Strand: Direct

Name: ydhC [C]

Synonym: PEPE_1688

Alternate gene names: 116493416

Gene position: 1664029-1665204 (Clockwise)

Preceding gene: 116493415

Following gene: 116493423

Centisome position: 90.81

GC content: 40.14

Gene sequence:

>1176_bases
ATGAAAAACGTCCGAAAACAAGTTCCATCTTTACTATTAATTATCGTTCTGGTTGGTTTTCCACAAATTAGTGAGTCCAT
CTTTACCCCTGCCTTACCAGCTTTAAGTTCGGCTCTGCAGGTTACCGCTCAGACGGGGCAATTAACCATGAGTTCTTATT
TCATCGCTTTTGCCCTAGGTGTTTTATTCTGGGGTAGTTACTCTGACCGTGTCGGTCGGCGTCCAGCGATGTTAGCAGGA
CTAATCGTTTACCTAGCTGGTAACATTGGATTACTGTGCGCTCCTAATTTTGCAATCCTAATTCTGTTTCGATTGGTCCA
ATCCTTTGGTGCCAGCGTCGGTTCTGTCGTAACACAATCCATCATGCGCGAATCCTTTGCTGGTGTAACCGGGGCGAAAG
TATTCGCTAAAGTTGGGGCTGCCTTAGCCCTCTCCCCTGCAATGGGACCATTATTAGGCGGAGTTACTCAGACTTATTTT
GGTTATCGTAATGTATTTTCTGTCTTAATTGTCATGGCAGTTAGTTTATATCTATATACACTTCGACGACTACCAGAAAC
TAATATCCAGTTATCTAACATCACTCATCAACCGGCATTCAAGCCTATTGTTATGCGTCTTTTAACTGATCCAAACGTTT
GGGTTTACGGCTTACTAATTAGTGGAATTAATGGCATTCTCTTCAGCTTCTATGCTGAAGCACCTTTTATCTTCATGGAA
CATTTTCATCTTAGTTCTATCCAATACGGTGTTTTAGGAGTAGTGGTTGCCTTATCTAGTATTTTCGGTTCTATAACCAT
TAATCACCTAGTCGCCAAGATCAGCGCCATTCAAATTACCAAATGGGGATTGATCCTAGCCATGTTTGGAGCCTTCCTAT
TAGTGGGTGCCAGTTGGATTGGAAATATTTACCTCTTTATTTTATGTATTTTTATCGTCTTTTTTGGTTTGTATATTACA
CTTCCAATGGCGCTTAATTTAGCACTCGTTGGTTACGAAGACGTGATTGGGGTAGCTAGTGGTATCTTTAGTTTTGGGTA
CTATATTTGTATCAGTTTCTTCACCTATCTAATTAGTGCATTTCATACCGGATGGATTGGAATCTTACCCTTGTATATCC
TAGCAATTACAGTCGTAATGTTACTTAGCTATGAGTTACGTTTTAAAAATAAATAA

Upstream 100 bases:

>100_bases
AAAGGGAGGAGTCTATTTGGCCTACGTTGGTTTTATCGCATCTGCTACCGTAATTAAATTAGGACGTTTTTCTGCATAAT
AAAATTTAAGGAGATTTAAA

Downstream 100 bases:

>100_bases
TCCATAAAATCAAAAAGACGCTTCTAATTTTAATTTAGAAGCGTCTTTTTCGGTCATCTTATGCAGCTTGCATGGCACTG
ATCAATTCATCGATCACTTT

Product: major facilitator superfamily permease

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MKNVRKQVPSLLLIIVLVGFPQISESIFTPALPALSSALQVTAQTGQLTMSSYFIAFALGVLFWGSYSDRVGRRPAMLAG
LIVYLAGNIGLLCAPNFAILILFRLVQSFGASVGSVVTQSIMRESFAGVTGAKVFAKVGAALALSPAMGPLLGGVTQTYF
GYRNVFSVLIVMAVSLYLYTLRRLPETNIQLSNITHQPAFKPIVMRLLTDPNVWVYGLLISGINGILFSFYAEAPFIFME
HFHLSSIQYGVLGVVVALSSIFGSITINHLVAKISAIQITKWGLILAMFGAFLLVGASWIGNIYLFILCIFIVFFGLYIT
LPMALNLALVGYEDVIGVASGIFSFGYYICISFFTYLISAFHTGWIGILPLYILAITVVMLLSYELRFKNK

Sequences:

>Translated_391_residues
MKNVRKQVPSLLLIIVLVGFPQISESIFTPALPALSSALQVTAQTGQLTMSSYFIAFALGVLFWGSYSDRVGRRPAMLAG
LIVYLAGNIGLLCAPNFAILILFRLVQSFGASVGSVVTQSIMRESFAGVTGAKVFAKVGAALALSPAMGPLLGGVTQTYF
GYRNVFSVLIVMAVSLYLYTLRRLPETNIQLSNITHQPAFKPIVMRLLTDPNVWVYGLLISGINGILFSFYAEAPFIFME
HFHLSSIQYGVLGVVVALSSIFGSITINHLVAKISAIQITKWGLILAMFGAFLLVGASWIGNIYLFILCIFIVFFGLYIT
LPMALNLALVGYEDVIGVASGIFSFGYYICISFFTYLISAFHTGWIGILPLYILAITVVMLLSYELRFKNK
>Mature_391_residues
MKNVRKQVPSLLLIIVLVGFPQISESIFTPALPALSSALQVTAQTGQLTMSSYFIAFALGVLFWGSYSDRVGRRPAMLAG
LIVYLAGNIGLLCAPNFAILILFRLVQSFGASVGSVVTQSIMRESFAGVTGAKVFAKVGAALALSPAMGPLLGGVTQTYF
GYRNVFSVLIVMAVSLYLYTLRRLPETNIQLSNITHQPAFKPIVMRLLTDPNVWVYGLLISGINGILFSFYAEAPFIFME
HFHLSSIQYGVLGVVVALSSIFGSITINHLVAKISAIQITKWGLILAMFGAFLLVGASWIGNIYLFILCIFIVFFGLYIT
LPMALNLALVGYEDVIGVASGIFSFGYYICISFFTYLISAFHTGWIGILPLYILAITVVMLLSYELRFKNK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=218, Percent_Identity=27.9816513761468, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788509, Length=395, Percent_Identity=24.3037974683544, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87082312, Length=332, Percent_Identity=23.4939759036145, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787065, Length=263, Percent_Identity=25.0950570342205, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790146, Length=167, Percent_Identity=23.3532934131737, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324264, Length=192, Percent_Identity=28.125, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42668; Mature: 42668

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVRKQVPSLLLIIVLVGFPQISESIFTPALPALSSALQVTAQTGQLTMSSYFIAFALG
CCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VLFWGSYSDRVGRRPAMLAGLIVYLAGNIGLLCAPNFAILILFRLVQSFGASVGSVVTQS
HHHHCCCHHHCCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHH
IMRESFAGVTGAKVFAKVGAALALSPAMGPLLGGVTQTYFGYRNVFSVLIVMAVSLYLYT
HHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRLPETNIQLSNITHQPAFKPIVMRLLTDPNVWVYGLLISGINGILFSFYAEAPFIFME
HHHCCCCCEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
HFHLSSIQYGVLGVVVALSSIFGSITINHLVAKISAIQITKWGLILAMFGAFLLVGASWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GNIYLFILCIFIVFFGLYITLPMALNLALVGYEDVIGVASGIFSFGYYICISFFTYLISA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHTGWIGILPLYILAITVVMLLSYELRFKNK
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNVRKQVPSLLLIIVLVGFPQISESIFTPALPALSSALQVTAQTGQLTMSSYFIAFALG
CCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
VLFWGSYSDRVGRRPAMLAGLIVYLAGNIGLLCAPNFAILILFRLVQSFGASVGSVVTQS
HHHHCCCHHHCCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCHHHHHHHHH
IMRESFAGVTGAKVFAKVGAALALSPAMGPLLGGVTQTYFGYRNVFSVLIVMAVSLYLYT
HHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRLPETNIQLSNITHQPAFKPIVMRLLTDPNVWVYGLLISGINGILFSFYAEAPFIFME
HHHCCCCCEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
HFHLSSIQYGVLGVVVALSSIFGSITINHLVAKISAIQITKWGLILAMFGAFLLVGASWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GNIYLFILCIFIVFFGLYITLPMALNLALVGYEDVIGVASGIFSFGYYICISFFTYLISA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FHTGWIGILPLYILAITVVMLLSYELRFKNK
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA