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The map label for this gene is yoeA [H]

Identifier: 116493308

GI number: 116493308

Start: 1548117

End: 1549457

Strand: Reverse

Name: yoeA [H]

Synonym: PEPE_1580

Alternate gene names: 116493308

Gene position: 1549457-1548117 (Counterclockwise)

Preceding gene: 116493309

Following gene: 116493307

Centisome position: 84.56

GC content: 40.87

Gene sequence:

>1341_bases
ATGGATAGTATTTTAACTAAGGGAAGTCCCATCAAGGGCATTATTTTGTTCAGTATCCCACTTCTTTTGGGAAATATTTT
CCAACAGATTTATACGCTTTCTGATACCTTGATTGTTGGTCGAGTAGTCGGTGTACAAGCATTGGCTTCTGTCGGGGCAA
CCAATGGACTTACTTTTTTGATTATTGGATTTGCGCAAGGGATGACAACGGGGTTATCGATTATTACGGCTCAGCACTAT
GGGGCTGGGGATGTTAAAGCAGTTAAGCAAAGTTTTGCTACGAGTATTTGGATTTGTGGCGTATTCGCCTTAATGCTGAC
GGTAGTTAGTGTACTGGCGGCTAGACCGTTGCTAGAAATGATGCAAACCCCAGCTAACATTATTGACGGTGCCACGACCT
TTTTGACGATCATTTTTGGTGGTGTGCTTGCAACTATGTTTTTTAACCTTTTCTCCAATATGTTACGTGCGTTGGGAAAT
AGTCGTTTGCCACTCGTATTTTTGGTAATCGCCTGTATTATCAACGTGGTATTGGATATTATTTTGATTGTCTTTTTACA
CATGGGAGTTGCTGGAGCCGGAATTGCTACGGTTACGGCCCAATTAATCTCATGCTTTCTATGCTGGTTCTATATTAAGT
CTCACGTTCCGGTTTTATCGCTTGAAGTAAAAGAAATTAAAACAAATATGAAATTGGTTCGTGAACAAATCAAGATTGGA
TTACCAATGGGGTTCCAGGCGTCCATTATCGCGATTGGGTCAATTATCCTACAAATTTCTTTGAACCATCTTGGATCATC
AGCAATTGCTGCTTATACTGCTGCTGGAAAAGTCGATCAGCTAGCAACGCAGCCAATGATGTCACTGGGGATCACAATGG
CAACCTTTACGGCTCAAAATTATGGGGCCAAAAAATTTAAACGTATTTTGAAAGGTATTCGTCAAACGTTGATCACTTCG
GTCGCTTACAGTTTTATTGTGGGTGCTTTAATTATTTTGAATAGTCGCGTACTGGTTAATCTATTTATTGGAAATTCAGA
ACAACATATCACCAACTTGGCGCATGAATATTTTGTGATCGTTAGTGCGAGTTATTTCTTGCTAGCAATCTTGTTCATCA
TCCGATATACCTTACAAGGATTCGGAAAGAGTGTGGCCCCAACGATGGCTGGGGTAGCCGAATTGATTTCAAGGATGTTA
GTGGGACTCTTTGTGGTTCCGGCTTTTGGATTTTGGGGAGCATGTACCGCTAACCCATTGGCTTGGTTAGGTTCAAATTT
AGTATTAGTTTATTCATACGTTCAAGTTGTACGACAATTGAGAAAACGTGCTGAGCCGTAG

Upstream 100 bases:

>100_bases
GCGGTTACCTACATGCGTACCCGTGATATTAAATGTAGTATTGGAATTCACATCTTAAATAATTTTATATCTTTTATTTA
ATAAAAAACGGAGGATTTAC

Downstream 100 bases:

>100_bases
AAAATGCTAAAAGAGCGTGAACACGATATAATCGAGGTATAGAAAGTAAATGCGTTGGGGGTAGAGTGATGATTTTTACT
TATAACGTTCTAAAGAATGT

Product: Na+-driven multidrug efflux pump

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MDSILTKGSPIKGIILFSIPLLLGNIFQQIYTLSDTLIVGRVVGVQALASVGATNGLTFLIIGFAQGMTTGLSIITAQHY
GAGDVKAVKQSFATSIWICGVFALMLTVVSVLAARPLLEMMQTPANIIDGATTFLTIIFGGVLATMFFNLFSNMLRALGN
SRLPLVFLVIACIINVVLDIILIVFLHMGVAGAGIATVTAQLISCFLCWFYIKSHVPVLSLEVKEIKTNMKLVREQIKIG
LPMGFQASIIAIGSIILQISLNHLGSSAIAAYTAAGKVDQLATQPMMSLGITMATFTAQNYGAKKFKRILKGIRQTLITS
VAYSFIVGALIILNSRVLVNLFIGNSEQHITNLAHEYFVIVSASYFLLAILFIIRYTLQGFGKSVAPTMAGVAELISRML
VGLFVVPAFGFWGACTANPLAWLGSNLVLVYSYVQVVRQLRKRAEP

Sequences:

>Translated_446_residues
MDSILTKGSPIKGIILFSIPLLLGNIFQQIYTLSDTLIVGRVVGVQALASVGATNGLTFLIIGFAQGMTTGLSIITAQHY
GAGDVKAVKQSFATSIWICGVFALMLTVVSVLAARPLLEMMQTPANIIDGATTFLTIIFGGVLATMFFNLFSNMLRALGN
SRLPLVFLVIACIINVVLDIILIVFLHMGVAGAGIATVTAQLISCFLCWFYIKSHVPVLSLEVKEIKTNMKLVREQIKIG
LPMGFQASIIAIGSIILQISLNHLGSSAIAAYTAAGKVDQLATQPMMSLGITMATFTAQNYGAKKFKRILKGIRQTLITS
VAYSFIVGALIILNSRVLVNLFIGNSEQHITNLAHEYFVIVSASYFLLAILFIIRYTLQGFGKSVAPTMAGVAELISRML
VGLFVVPAFGFWGACTANPLAWLGSNLVLVYSYVQVVRQLRKRAEP
>Mature_446_residues
MDSILTKGSPIKGIILFSIPLLLGNIFQQIYTLSDTLIVGRVVGVQALASVGATNGLTFLIIGFAQGMTTGLSIITAQHY
GAGDVKAVKQSFATSIWICGVFALMLTVVSVLAARPLLEMMQTPANIIDGATTFLTIIFGGVLATMFFNLFSNMLRALGN
SRLPLVFLVIACIINVVLDIILIVFLHMGVAGAGIATVTAQLISCFLCWFYIKSHVPVLSLEVKEIKTNMKLVREQIKIG
LPMGFQASIIAIGSIILQISLNHLGSSAIAAYTAAGKVDQLATQPMMSLGITMATFTAQNYGAKKFKRILKGIRQTLITS
VAYSFIVGALIILNSRVLVNLFIGNSEQHITNLAHEYFVIVSASYFLLAILFIIRYTLQGFGKSVAPTMAGVAELISRML
VGLFVVPAFGFWGACTANPLAWLGSNLVLVYSYVQVVRQLRKRAEP

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48038; Mature: 48038

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]