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The map label for this gene is galE [H]

Identifier: 116493213

GI number: 116493213

Start: 1448074

End: 1449066

Strand: Reverse

Name: galE [H]

Synonym: PEPE_1475

Alternate gene names: 116493213

Gene position: 1449066-1448074 (Counterclockwise)

Preceding gene: 116493214

Following gene: 116493212

Centisome position: 79.08

GC content: 39.88

Gene sequence:

>993_bases
ATGAGTATTCTTGTAGTTGGAGGAGCCGGATATATTGGTTCACATATGGTTAAGCGATTAGTCGAACAAAATCGAGATGT
AGTCGTTGTGGATAACTTATCAACTGGTCATCGTGGCGCAGTGGATAAAGGCGTAAAATTTTATGAGGGCGATATCCGAG
ATCATGCCTTTTTAAAGGAAGTCTTTGATCAAGAAGCAATTGACACAGTTGTGCATTTTGCTGCATTTTCAATTGTTCCT
GAATCCATGGAAAAACCGCTTAAGTATTTTGATAATAATACGGCAGGAATGGTTGCTCTTCTTGAAGAAATGCGGGATCA
CGATGTAAAACGCATTATTTTCTCATCTACAGCTGCTACTTATGGAGTTCCTGAAAAGTCTCCGATCGAAGAAACCGACC
GTCAAGCCCCTATCAATCCTTACGGTGAAAGTAAATTAATGATGGAAAAAATCATTAAATGGGCGGATCAAGCTTATGGA
ATCAAATTTGTAGCCCTCCGCTACTTTAACGTAGCAGGAGCCTATCCAGATGGTTCAATTGGCGAAGATCATGGACCAGA
AACTCATTTAACACCAATTATCTTGCAAGTGGCTTTAGGCAAACGTGACCAATTACAAATTTTTGGAGATGACTATCATA
CTCCAGATGGTACGAACGTACGTGACTATGTGCACGTTTTAGATCTTGCGGATGCTCATATTTTAGCAATCGATTATCTT
AAAGCAGGTAATGATAGCGACGTCTTCAATTTAGGTTCATCAACTGGTTTCTCAGTTAAAGAAATGGTTGAAGCAGCACG
TGAAGCAACTGGTGAAGCCATTCCAGCTAAAATTGCGGCTCGTCGTCCTGGAGATCCAGATTCATTAATTGCTGCAAGTC
AAAAAGCACGCAAAATCTTAAAATGGAATCCTCAATATGATGACGTTAAAGAAATCATTAAAACTGCGTGGAATTGGACT
CAGAAACATCCCAATGGTTATGAAGACCACTAA

Upstream 100 bases:

>100_bases
TTTTGCTAATGACACTTTGTGTTGTGAAGCAAATGTTGAATGGAATCACCGTTAAGGTTACAATGAGCGTAGTTTAAATT
TTACATTGGAGGATGAATGA

Downstream 100 bases:

>100_bases
AATAAACGTATAAATAATTTTAATTGAGGTTATGACATAAAAATTTGTCATAACCTCTTTAATTTTGAAAGAAATGACCT
TGAAAGGACGAATTTATTCT

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MSILVVGGAGYIGSHMVKRLVEQNRDVVVVDNLSTGHRGAVDKGVKFYEGDIRDHAFLKEVFDQEAIDTVVHFAAFSIVP
ESMEKPLKYFDNNTAGMVALLEEMRDHDVKRIIFSSTAATYGVPEKSPIEETDRQAPINPYGESKLMMEKIIKWADQAYG
IKFVALRYFNVAGAYPDGSIGEDHGPETHLTPIILQVALGKRDQLQIFGDDYHTPDGTNVRDYVHVLDLADAHILAIDYL
KAGNDSDVFNLGSSTGFSVKEMVEAAREATGEAIPAKIAARRPGDPDSLIAASQKARKILKWNPQYDDVKEIIKTAWNWT
QKHPNGYEDH

Sequences:

>Translated_330_residues
MSILVVGGAGYIGSHMVKRLVEQNRDVVVVDNLSTGHRGAVDKGVKFYEGDIRDHAFLKEVFDQEAIDTVVHFAAFSIVP
ESMEKPLKYFDNNTAGMVALLEEMRDHDVKRIIFSSTAATYGVPEKSPIEETDRQAPINPYGESKLMMEKIIKWADQAYG
IKFVALRYFNVAGAYPDGSIGEDHGPETHLTPIILQVALGKRDQLQIFGDDYHTPDGTNVRDYVHVLDLADAHILAIDYL
KAGNDSDVFNLGSSTGFSVKEMVEAAREATGEAIPAKIAARRPGDPDSLIAASQKARKILKWNPQYDDVKEIIKTAWNWT
QKHPNGYEDH
>Mature_329_residues
SILVVGGAGYIGSHMVKRLVEQNRDVVVVDNLSTGHRGAVDKGVKFYEGDIRDHAFLKEVFDQEAIDTVVHFAAFSIVPE
SMEKPLKYFDNNTAGMVALLEEMRDHDVKRIIFSSTAATYGVPEKSPIEETDRQAPINPYGESKLMMEKIIKWADQAYGI
KFVALRYFNVAGAYPDGSIGEDHGPETHLTPIILQVALGKRDQLQIFGDDYHTPDGTNVRDYVHVLDLADAHILAIDYLK
AGNDSDVFNLGSSTGFSVKEMVEAAREATGEAIPAKIAARRPGDPDSLIAASQKARKILKWNPQYDDVKEIIKTAWNWTQ
KHPNGYEDH

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=40.5247813411079, Blast_Score=258, Evalue=7e-69,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=40.5247813411079, Blast_Score=258, Evalue=7e-69,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=40.5247813411079, Blast_Score=258, Evalue=7e-69,
Organism=Homo sapiens, GI7657641, Length=343, Percent_Identity=26.2390670553936, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI42516563, Length=314, Percent_Identity=24.8407643312102, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI193211614, Length=239, Percent_Identity=26.3598326359833, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI8393516, Length=239, Percent_Identity=26.3598326359833, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1786974, Length=339, Percent_Identity=43.0678466076696, Blast_Score=270, Evalue=9e-74,
Organism=Escherichia coli, GI1788353, Length=339, Percent_Identity=29.2035398230088, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=30.2395209580838, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790049, Length=272, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788589, Length=287, Percent_Identity=25.0871080139373, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=349, Percent_Identity=39.2550143266476, Blast_Score=244, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI71982038, Length=351, Percent_Identity=39.031339031339, Blast_Score=244, Evalue=6e-65,
Organism=Caenorhabditis elegans, GI17539532, Length=329, Percent_Identity=24.6200607902736, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115532424, Length=333, Percent_Identity=23.4234234234234, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17568069, Length=304, Percent_Identity=25, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=42.7325581395349, Blast_Score=266, Evalue=5e-72,
Organism=Saccharomyces cerevisiae, GI6321437, Length=255, Percent_Identity=25.4901960784314, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19923002, Length=348, Percent_Identity=38.2183908045977, Blast_Score=240, Evalue=9e-64,
Organism=Drosophila melanogaster, GI21356223, Length=314, Percent_Identity=26.4331210191083, Blast_Score=98, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36674; Mature: 36543

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVVGGAGYIGSHMVKRLVEQNRDVVVVDNLSTGHRGAVDKGVKFYEGDIRDHAFLKE
CEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHCCCCEEECCCHHHHHHHH
VFDQEAIDTVVHFAAFSIVPESMEKPLKYFDNNTAGMVALLEEMRDHDVKRIIFSSTAAT
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YGVPEKSPIEETDRQAPINPYGESKLMMEKIIKWADQAYGIKFVALRYFNVAGAYPDGSI
CCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEHHHHCCCCCCCCC
GEDHGPETHLTPIILQVALGKRDQLQIFGDDYHTPDGTNVRDYVHVLDLADAHILAIDYL
CCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHH
KAGNDSDVFNLGSSTGFSVKEMVEAAREATGEAIPAKIAARRPGDPDSLIAASQKARKIL
HCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHH
KWNPQYDDVKEIIKTAWNWTQKHPNGYEDH
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SILVVGGAGYIGSHMVKRLVEQNRDVVVVDNLSTGHRGAVDKGVKFYEGDIRDHAFLKE
EEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHCCCCEEECCCHHHHHHHH
VFDQEAIDTVVHFAAFSIVPESMEKPLKYFDNNTAGMVALLEEMRDHDVKRIIFSSTAAT
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YGVPEKSPIEETDRQAPINPYGESKLMMEKIIKWADQAYGIKFVALRYFNVAGAYPDGSI
CCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEHHHHCCCCCCCCC
GEDHGPETHLTPIILQVALGKRDQLQIFGDDYHTPDGTNVRDYVHVLDLADAHILAIDYL
CCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEHH
KAGNDSDVFNLGSSTGFSVKEMVEAAREATGEAIPAKIAARRPGDPDSLIAASQKARKIL
HCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHH
KWNPQYDDVKEIIKTAWNWTQKHPNGYEDH
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]