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The map label for this gene is 116493175

Identifier: 116493175

GI number: 116493175

Start: 1411670

End: 1412302

Strand: Reverse

Name: 116493175

Synonym: PEPE_1437

Alternate gene names: NA

Gene position: 1412302-1411670 (Counterclockwise)

Preceding gene: 116493176

Following gene: 116493174

Centisome position: 77.07

GC content: 33.81

Gene sequence:

>633_bases
ATGATTGCTTTATCAGGCCCAATTGGCGCAGGAAAGACAACACTTACAGAATTATTAACAAGTCACTGGGAAAGTGATGC
TTATTACGAATCAGTAGATGATAATAAAATTTTGCCACTTTTCTACAAAGATCCTAAACGCTATGCGTTCTTACTTCAAA
TTTACTTTTTGAATAAACGTATGGATAGTATCAAGCAAGCTAATAGCGATGCTCGTAGTGTTATGGACCGTTCGATTTAT
GAAGATTCACTTTTGTTCCATTTGAACGCTGATTTAGGACGAGCAACTAATACAGAAGTGGATATTTACGATTCGTTACT
TAAAAATATGATGCAAGAGTTGCCACGTCTTTCATATAAGAAGAATCCCGATTTACTAGTTCATATTGATATTTCGTTTG
ATACAATGTTAAAACGGATCAAAAAGCGCGGTCGTTCATTCGAACAAATCGAAAATGATCCATCATTATACGAATACTAT
CACGAACTCAATAAGCGCTATGTTGCTTGGTTCGATAATTATGATCAAAGTGCTAAAATTAAAATTGACGGTGATAAATA
TGATTTTGTGGAAAATCCAGAAGCTCGTCAAAAAGTTATTCAACTAATTGATGAAAAGATTGCCACAATTTAA

Upstream 100 bases:

>100_bases
CAGATATCACGAAAGAATAATTTTTTCAAGATATTGTTTTGGGGTCGTTTGGTGGTACAATATGTAGTGCTAAAAAACGA
AAAAAGAGGTATTTCTTATA

Downstream 100 bases:

>100_bases
TTGATATCTACCCGGCTTTTTTGTAGAATTAGTTTATAAATTAATAGAGAAATTAAAGGCGTTTAAAGTAGGTTTTTAGA
GAGATCCGCATGGTGGAAAG

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGK; DGUO kinase; Deoxynucleoside kinase complex I F-component [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MIALSGPIGAGKTTLTELLTSHWESDAYYESVDDNKILPLFYKDPKRYAFLLQIYFLNKRMDSIKQANSDARSVMDRSIY
EDSLLFHLNADLGRATNTEVDIYDSLLKNMMQELPRLSYKKNPDLLVHIDISFDTMLKRIKKRGRSFEQIENDPSLYEYY
HELNKRYVAWFDNYDQSAKIKIDGDKYDFVENPEARQKVIQLIDEKIATI

Sequences:

>Translated_210_residues
MIALSGPIGAGKTTLTELLTSHWESDAYYESVDDNKILPLFYKDPKRYAFLLQIYFLNKRMDSIKQANSDARSVMDRSIY
EDSLLFHLNADLGRATNTEVDIYDSLLKNMMQELPRLSYKKNPDLLVHIDISFDTMLKRIKKRGRSFEQIENDPSLYEYY
HELNKRYVAWFDNYDQSAKIKIDGDKYDFVENPEARQKVIQLIDEKIATI
>Mature_210_residues
MIALSGPIGAGKTTLTELLTSHWESDAYYESVDDNKILPLFYKDPKRYAFLLQIYFLNKRMDSIKQANSDARSVMDRSIY
EDSLLFHLNADLGRATNTEVDIYDSLLKNMMQELPRLSYKKNPDLLVHIDISFDTMLKRIKKRGRSFEQIENDPSLYEYY
HELNKRYVAWFDNYDQSAKIKIDGDKYDFVENPEARQKVIQLIDEKIATI

Specific function: DGK/DAK plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism [H]

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24671; Mature: 24671

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALSGPIGAGKTTLTELLTSHWESDAYYESVDDNKILPLFYKDPKRYAFLLQIYFLNKR
CEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
MDSIKQANSDARSVMDRSIYEDSLLFHLNADLGRATNTEVDIYDSLLKNMMQELPRLSYK
HHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
KNPDLLVHIDISFDTMLKRIKKRGRSFEQIENDPSLYEYYHELNKRYVAWFDNYDQSAKI
CCCCEEEEEECCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCEEE
KIDGDKYDFVENPEARQKVIQLIDEKIATI
EECCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIALSGPIGAGKTTLTELLTSHWESDAYYESVDDNKILPLFYKDPKRYAFLLQIYFLNKR
CEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
MDSIKQANSDARSVMDRSIYEDSLLFHLNADLGRATNTEVDIYDSLLKNMMQELPRLSYK
HHHHHHCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
KNPDLLVHIDISFDTMLKRIKKRGRSFEQIENDPSLYEYYHELNKRYVAWFDNYDQSAKI
CCCCEEEEEECCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCEEE
KIDGDKYDFVENPEARQKVIQLIDEKIATI
EECCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7896798; 8172906 [H]