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The map label for this gene is rpoB

Identifier: 116493170

GI number: 116493170

Start: 1402290

End: 1405898

Strand: Reverse

Name: rpoB

Synonym: PEPE_1426

Alternate gene names: 116493170

Gene position: 1405898-1402290 (Counterclockwise)

Preceding gene: 116493171

Following gene: 116493169

Centisome position: 76.72

GC content: 40.57

Gene sequence:

>3609_bases
TTGGCAGGACATTTAGTTAAGTATGGTAAACATCGTACGCGCCGGAGCTATGCACGAATTAAAGAAGTGCTTGATCTACC
TAATTTGATCGAGATTCAATCTGATTCGTACCAATGGTTCTTAGACGAAGGTCTCCGTGAAATGTTCAATGACATTATGC
CGATTGAAGATTTTGCAGGTAAATTATCACTTGAATTCGTCGATTATCAACTACTAGAACCAAAGTACACGGTTGACGAA
GCTCGTGAACATGAAGCAAACTATTCTGCACCATTGCACGTAACTTTACGTTTAACAAACCACGAAACTGGCGAAATTAA
ATCACAAGACGTATTCTTTGGTGATTTCCCATTAATGACAGAACAAGGTACTTTCATTATTAATGGAGCAGAACGTGTTA
TTGTTTCACAATTAGTTCGTTCACCTGGTGTCTATTACAACTTAGATACAGATAAAAATAATCGTAAAATTTGGGGAACA
ACCGTTATTCCTAACCGTGGGGCTTGGTTAGAATATGAAACAGATGCTAAAGAAATTTCTTATGTACGGATTGATCGTAC
TCGTAAGATTCCAATGACCGAATTAGTTCGTGCCCTTGGATTTGGCTCTGATGAAGAAATCATCGATATTTTTGGTGGTT
CTGATAGTTTAGATTTCACTCTTGATAAAGATGTTCATAAGAATCCCGAAGATTCACGGGTTGCTGAATCATTGAAGGAT
ATTTACGAACGTTTGCGTCCTGGTGAACCTAAGACTGCAGATAGTTCAAGAAGTTTGCTAACTGCGCGCTTCTTTGATCC
AAAACGTTACGACATGGCTCCAGTAGGTCGTTACAAAGTAAATAAAAAACTTAGCCTTAAGACTCGTCTTTTAGGTCAAA
CCCTAGCTGAAACATTAGCTGATCCTGATACAGGGGAAGTTATTGCTCAAAAGGGTGAAATGGTCAACAAAGACGTAATG
AAGAAATTAGCAGTTTTCCTTGATCGTCCTGACTTCAAGATGGTTACATACCAACCATCTGAAGAAGCAGTCGTTACTGA
ACCAATGACTATCCAAGTTATCAAAGTTCAAGACCCTAACGACCCAGAACGTACATTGAATATGATTGGTAATGGTAATA
TCGATGCTAAATTGAAGCACATCACACCTGCTGATATTATTGCTTCAATGAATTACTTCTTCCTTCTTCAAGATGGAATT
GGTAGTACAGATGATATTGATCATTTGGGTAACCGTCGAATCCGTTCAGTTGGTGAACTACTTCAAAACCAATTCCGCAT
TGGTTTATCACGTATGGAACGTGTAGTACGTGAACGTATGTCAATCCAAGATGCTGAAACAGTTACACCACAACAATTGA
TTAACATTCGTCCAGTAGTTGCTGCAACTAAAGAATTCTTTGGTTCTTCACAATTGTCACAATTCATGGATCAAACTAAC
CCGCTTGGTGAATTATCACATAAGCGTCGTCTATCAGCACTTGGACCTGGTGGTTTGACTCGTGATCGTGCCGGATATGA
AGTTCGAGACGTTCACTATACGCATTATGGTCGTATGTGTCCGATTGAAACTCCCGAAGGTCCTAATATCGGTTTGATTA
ATAACTTGGCTTCATATGGTAAGATCAACCGTTATGGTTTTATCGAAACACCATATCGTCGTGTTTCATGGGAAGATCAT
AAAGTTACCGATCGTATTGATTACTTAACTGCTGACGAAGAAGATCAATTTGTTATTGCTCAGGCTAACTCTCCACTTAA
TGATGATGGTTCATTTGCTGACGACGTAGTTATGGCTCGTCATGAAAGTGATAACATCGAAACTAGCATTGAAAATGTCG
ATTACATGGACGTTTCTCCTAAGCAAGTAGTTGCTGTTGCTACAGCATGTATTCCTTTCTTGGAAAATGATGATTCTAAC
CGTGCCTTGATGGGTGCTAATATGCAACGTCAGGCTGTTCCATTGGTTGATCCACATTCTCCATTAATTGGTACTGGTAT
TGAATATAAAGCTGCGCATGATTCTGGGGTTGCTCTTTTATGTCAACACGCTGGTGTAGTTGAATATGTTGATGCACGTG
AAGTACGTGTCCGTCGTGATGATGGCGCACTTGATACTTACAAGCTCATGAAGTTCCGCCGTTCAAATGGTGGTAAGAAC
TACAACCAACGCCCAATTGTTCGAGTTAATGATAAAGTTGACGCGGATGAAGTACTAGCTGATGGTCCATCAATGGAACA
AGGTGAATTAGCCCTTGGACAAAACCCATTGATCGCCTTCATGACATGGCAAGGTTATAACTTCGAAGATGCGATTGCGA
TTAATGAACGTTTAGTTCGTGATGACGTATATACATCAATTCATATCGAAGAATATGAATCAGAAGCACGTGATACAAAA
CTTGGACCTGAAGAAATGACTCGTGAAATTCCTAATATTGGTGAAGATGCCCTTCGCAATCTTGATCAAGATGGTATTGT
TCGAGTTGGTGCTGAAGTTGAAGATGGTGACATCTTGGTTGGTAAGGTTACTCCTAAGGGGGTCACAGAATTATCTGCTG
AAGAACGCTTGCTTCATGCTATTTTCGGTGAAAAAGCTCGTGAAGTTCGTGATACATCACTCCGTGTTCCACATGGTGGC
GGCGGAATCGTTCAAGACGTTAAGATTTTCACTCGTGAAAATGGTGACGAATTATCACCTGGTGTAAACATGATGGTTCG
TGTTTATATCGCTCAAAAGCGTAAACTCCAAGTTGGTGATAAGATGGCCGGACGTCATGGTAACAAAGGTACTGTTTCAG
TGGTTATCCCACAAGAAGATATGCCTTACATGCCTGATGGAACTCCAATTGACATTATGCTTAGCCCAATGGGTGTGCCT
TCTCGTATGAATATCGGACAAGTTCTTGAACTTCATTTGGGAATGGCTGCACGTAACTTAGGTATCCACATGACAACTCC
TGTTTTTGATGGAGCCCAAGATAAAGATATTTGGGAAGCAGTTGCTGAAGCTGGTATGGATTCTGATGCTAAGTCTGTGC
TTTATGATGGACGTACTGGTGAACCATTTGAACAACGTGTGGCTGTTGGTGTCATGCACTATATGAAACTTGCTCACATG
GTTGATGATAAGATTCATGCTCGTTCAATTGGACCTTACTCACTTGTTACACAACAACCACTTGGTGGTAAAGCACAATT
TGGTGGACAGCGTTTTGGTGAAATGGAAGTTTGGGCTCTTGAAGCTTACGGTGCTGCATATACTCTTCAAGAAATCCTTA
CTTACAAGTCTGATGACGTCGTTGGTCGAGTTAAGACATACGAAGCGATCGTTAAGGGTGAACCAATTCCACGCCCAGGT
GTTCCAGAATCATTCCGAGTTCTTGTTAAAGAATTACAAGCTTTAGGACTTGATATGAAGGTTCTAGGTGGGGATGACCA
AGAAGTTGAACTTCGTGATATGGACGAAGAAGATGACGATGTTGTGAATGTCGATGCTCTTAGCAAGTATGCTGAAAAGC
AAAATGAAAAAACAAATGCTAGCGCTGAAGAAGCAAAGGCTCCATCAACGGAATCAGCTCCTGTTGAAACTAAAAACAAT
CAAAACTAA

Upstream 100 bases:

>100_bases
GGACTATTTTTGGTTTTTTTTTGCTAAAAAACAGGTTTCAGTGCAAATTGTAATCAAACTGTAACATTTAACTCGTTTAG
AAATTGGAGAGGTGAATAAC

Downstream 100 bases:

>100_bases
TTACTTAAAAGAAAGAGGAGGTCAGTCCGTTGATCGATGTTAATAAATTCGAAAGTATGCAAATCGGTTTAGCTTCTCCT
GATAAGATCCGTATGTGGTC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1202; Mature: 1201

Protein sequence:

>1202_residues
MAGHLVKYGKHRTRRSYARIKEVLDLPNLIEIQSDSYQWFLDEGLREMFNDIMPIEDFAGKLSLEFVDYQLLEPKYTVDE
AREHEANYSAPLHVTLRLTNHETGEIKSQDVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYNLDTDKNNRKIWGT
TVIPNRGAWLEYETDAKEISYVRIDRTRKIPMTELVRALGFGSDEEIIDIFGGSDSLDFTLDKDVHKNPEDSRVAESLKD
IYERLRPGEPKTADSSRSLLTARFFDPKRYDMAPVGRYKVNKKLSLKTRLLGQTLAETLADPDTGEVIAQKGEMVNKDVM
KKLAVFLDRPDFKMVTYQPSEEAVVTEPMTIQVIKVQDPNDPERTLNMIGNGNIDAKLKHITPADIIASMNYFFLLQDGI
GSTDDIDHLGNRRIRSVGELLQNQFRIGLSRMERVVRERMSIQDAETVTPQQLINIRPVVAATKEFFGSSQLSQFMDQTN
PLGELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLASYGKINRYGFIETPYRRVSWEDH
KVTDRIDYLTADEEDQFVIAQANSPLNDDGSFADDVVMARHESDNIETSIENVDYMDVSPKQVVAVATACIPFLENDDSN
RALMGANMQRQAVPLVDPHSPLIGTGIEYKAAHDSGVALLCQHAGVVEYVDAREVRVRRDDGALDTYKLMKFRRSNGGKN
YNQRPIVRVNDKVDADEVLADGPSMEQGELALGQNPLIAFMTWQGYNFEDAIAINERLVRDDVYTSIHIEEYESEARDTK
LGPEEMTREIPNIGEDALRNLDQDGIVRVGAEVEDGDILVGKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLRVPHGG
GGIVQDVKIFTRENGDELSPGVNMMVRVYIAQKRKLQVGDKMAGRHGNKGTVSVVIPQEDMPYMPDGTPIDIMLSPMGVP
SRMNIGQVLELHLGMAARNLGIHMTTPVFDGAQDKDIWEAVAEAGMDSDAKSVLYDGRTGEPFEQRVAVGVMHYMKLAHM
VDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDVVGRVKTYEAIVKGEPIPRPG
VPESFRVLVKELQALGLDMKVLGGDDQEVELRDMDEEDDDVVNVDALSKYAEKQNEKTNASAEEAKAPSTESAPVETKNN
QN

Sequences:

>Translated_1202_residues
MAGHLVKYGKHRTRRSYARIKEVLDLPNLIEIQSDSYQWFLDEGLREMFNDIMPIEDFAGKLSLEFVDYQLLEPKYTVDE
AREHEANYSAPLHVTLRLTNHETGEIKSQDVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYNLDTDKNNRKIWGT
TVIPNRGAWLEYETDAKEISYVRIDRTRKIPMTELVRALGFGSDEEIIDIFGGSDSLDFTLDKDVHKNPEDSRVAESLKD
IYERLRPGEPKTADSSRSLLTARFFDPKRYDMAPVGRYKVNKKLSLKTRLLGQTLAETLADPDTGEVIAQKGEMVNKDVM
KKLAVFLDRPDFKMVTYQPSEEAVVTEPMTIQVIKVQDPNDPERTLNMIGNGNIDAKLKHITPADIIASMNYFFLLQDGI
GSTDDIDHLGNRRIRSVGELLQNQFRIGLSRMERVVRERMSIQDAETVTPQQLINIRPVVAATKEFFGSSQLSQFMDQTN
PLGELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLASYGKINRYGFIETPYRRVSWEDH
KVTDRIDYLTADEEDQFVIAQANSPLNDDGSFADDVVMARHESDNIETSIENVDYMDVSPKQVVAVATACIPFLENDDSN
RALMGANMQRQAVPLVDPHSPLIGTGIEYKAAHDSGVALLCQHAGVVEYVDAREVRVRRDDGALDTYKLMKFRRSNGGKN
YNQRPIVRVNDKVDADEVLADGPSMEQGELALGQNPLIAFMTWQGYNFEDAIAINERLVRDDVYTSIHIEEYESEARDTK
LGPEEMTREIPNIGEDALRNLDQDGIVRVGAEVEDGDILVGKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLRVPHGG
GGIVQDVKIFTRENGDELSPGVNMMVRVYIAQKRKLQVGDKMAGRHGNKGTVSVVIPQEDMPYMPDGTPIDIMLSPMGVP
SRMNIGQVLELHLGMAARNLGIHMTTPVFDGAQDKDIWEAVAEAGMDSDAKSVLYDGRTGEPFEQRVAVGVMHYMKLAHM
VDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDVVGRVKTYEAIVKGEPIPRPG
VPESFRVLVKELQALGLDMKVLGGDDQEVELRDMDEEDDDVVNVDALSKYAEKQNEKTNASAEEAKAPSTESAPVETKNN
QN
>Mature_1201_residues
AGHLVKYGKHRTRRSYARIKEVLDLPNLIEIQSDSYQWFLDEGLREMFNDIMPIEDFAGKLSLEFVDYQLLEPKYTVDEA
REHEANYSAPLHVTLRLTNHETGEIKSQDVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYNLDTDKNNRKIWGTT
VIPNRGAWLEYETDAKEISYVRIDRTRKIPMTELVRALGFGSDEEIIDIFGGSDSLDFTLDKDVHKNPEDSRVAESLKDI
YERLRPGEPKTADSSRSLLTARFFDPKRYDMAPVGRYKVNKKLSLKTRLLGQTLAETLADPDTGEVIAQKGEMVNKDVMK
KLAVFLDRPDFKMVTYQPSEEAVVTEPMTIQVIKVQDPNDPERTLNMIGNGNIDAKLKHITPADIIASMNYFFLLQDGIG
STDDIDHLGNRRIRSVGELLQNQFRIGLSRMERVVRERMSIQDAETVTPQQLINIRPVVAATKEFFGSSQLSQFMDQTNP
LGELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLASYGKINRYGFIETPYRRVSWEDHK
VTDRIDYLTADEEDQFVIAQANSPLNDDGSFADDVVMARHESDNIETSIENVDYMDVSPKQVVAVATACIPFLENDDSNR
ALMGANMQRQAVPLVDPHSPLIGTGIEYKAAHDSGVALLCQHAGVVEYVDAREVRVRRDDGALDTYKLMKFRRSNGGKNY
NQRPIVRVNDKVDADEVLADGPSMEQGELALGQNPLIAFMTWQGYNFEDAIAINERLVRDDVYTSIHIEEYESEARDTKL
GPEEMTREIPNIGEDALRNLDQDGIVRVGAEVEDGDILVGKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLRVPHGGG
GIVQDVKIFTRENGDELSPGVNMMVRVYIAQKRKLQVGDKMAGRHGNKGTVSVVIPQEDMPYMPDGTPIDIMLSPMGVPS
RMNIGQVLELHLGMAARNLGIHMTTPVFDGAQDKDIWEAVAEAGMDSDAKSVLYDGRTGEPFEQRVAVGVMHYMKLAHMV
DDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDVVGRVKTYEAIVKGEPIPRPGV
PESFRVLVKELQALGLDMKVLGGDDQEVELRDMDEEDDDVVNVDALSKYAEKQNEKTNASAEEAKAPSTESAPVETKNNQ
N

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908503, Length=850, Percent_Identity=25.7647058823529, Blast_Score=204, Evalue=4e-52,
Organism=Homo sapiens, GI238908505, Length=850, Percent_Identity=25.7647058823529, Blast_Score=204, Evalue=6e-52,
Organism=Homo sapiens, GI4505941, Length=736, Percent_Identity=25.9510869565217, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI212286172, Length=421, Percent_Identity=28.978622327791, Blast_Score=161, Evalue=3e-39,
Organism=Homo sapiens, GI33469941, Length=421, Percent_Identity=28.978622327791, Blast_Score=161, Evalue=3e-39,
Organism=Escherichia coli, GI1790419, Length=953, Percent_Identity=45.2256033578174, Blast_Score=786, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=408, Percent_Identity=30.8823529411765, Blast_Score=187, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17552304, Length=740, Percent_Identity=25.6756756756757, Blast_Score=183, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI17506623, Length=365, Percent_Identity=29.3150684931507, Blast_Score=134, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6324725, Length=444, Percent_Identity=29.5045045045045, Blast_Score=184, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6324781, Length=437, Percent_Identity=28.3752860411899, Blast_Score=168, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6325267, Length=553, Percent_Identity=26.5822784810127, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI17136444, Length=676, Percent_Identity=26.3313609467456, Blast_Score=188, Evalue=2e-47,
Organism=Drosophila melanogaster, GI17647877, Length=471, Percent_Identity=28.8747346072187, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI17136446, Length=360, Percent_Identity=30.5555555555556, Blast_Score=135, Evalue=1e-31,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_PEDPA (Q03EA9)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804905.1
- ProteinModelPortal:   Q03EA9
- STRING:   Q03EA9
- GeneID:   4417295
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1426
- NMPDR:   fig|278197.10.peg.1259
- eggNOG:   COG0085
- HOGENOM:   HBG285547
- OMA:   FMTWEGY
- PhylomeDB:   Q03EA9
- ProtClustDB:   PRK00405
- BioCyc:   PPEN278197:PEPE_1426-MONOMER
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 134622; Mature: 134490

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGHLVKYGKHRTRRSYARIKEVLDLPNLIEIQSDSYQWFLDEGLREMFNDIMPIEDFAG
CCCCCCHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHHHHCCCHHHHCC
KLSLEFVDYQLLEPKYTVDEAREHEANYSAPLHVTLRLTNHETGEIKSQDVFFGDFPLMT
CEEEEEECEEECCCCCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCCEEE
EQGTFIINGAERVIVSQLVRSPGVYYNLDTDKNNRKIWGTTVIPNRGAWLEYETDAKEIS
CCCCEEECCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCCCEEEECCCCCCEE
YVRIDRTRKIPMTELVRALGFGSDEEIIDIFGGSDSLDFTLDKDVHKNPEDSRVAESLKD
EEEECCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCCCCCCCHHHHHHHHHH
IYERLRPGEPKTADSSRSLLTARFFDPKRYDMAPVGRYKVNKKLSLKTRLLGQTLAETLA
HHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHC
DPDTGEVIAQKGEMVNKDVMKKLAVFLDRPDFKMVTYQPSEEAVVTEPMTIQVIKVQDPN
CCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEECCEEEEEEEECCCC
DPERTLNMIGNGNIDAKLKHITPADIIASMNYFFLLQDGIGSTDDIDHLGNRRIRSVGEL
CHHHHHHHHCCCCCCEEEECCCHHHHHHCCCEEEEEECCCCCCCCHHHHCCHHHHHHHHH
LQNQFRIGLSRMERVVRERMSIQDAETVTPQQLINIRPVVAATKEFFGSSQLSQFMDQTN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHCHHHHHHHHHCCC
PLGELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLASYG
CHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHC
KINRYGFIETPYRRVSWEDHKVTDRIDYLTADEEDQFVIAQANSPLNDDGSFADDVVMAR
CCCCCCCCCCCHHHCCCCCCCHHHHHHEEECCCCCCEEEEECCCCCCCCCCCHHHHHEEE
HESDNIETSIENVDYMDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLVDPHS
CCCCCCHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCC
PLIGTGIEYKAAHDSGVALLCQHAGVVEYVDAREVRVRRDDGALDTYKLMKFRRSNGGKN
CCCCCCCEEEECCCCCEEEEECCCCCEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCC
YNQRPIVRVNDKVDADEVLADGPSMEQGELALGQNPLIAFMTWQGYNFEDAIAINERLVR
CCCCCEEEECCCCCHHHHHCCCCCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHH
DDVYTSIHIEEYESEARDTKLGPEEMTREIPNIGEDALRNLDQDGIVRVGAEVEDGDILV
HHHHEEEEEHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHCCCCCCEEEECCEECCCCEEE
GKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLRVPHGGGGIVQDVKIFTRENGDELSP
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCEEEEEEECCCCCCCCC
GVNMMVRVYIAQKRKLQVGDKMAGRHGNKGTVSVVIPQEDMPYMPDGTPIDIMLSPMGVP
CHHEEEEEEEHHCCHHCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCC
SRMNIGQVLELHLGMAARNLGIHMTTPVFDGAQDKDIWEAVAEAGMDSDAKSVLYDGRTG
CCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHHEECCCCC
EPFEQRVAVGVMHYMKLAHMVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWAL
CCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCHHEEECCCCCCCCCCCCCCCCCEEEEEE
EAYGAAYTLQEILTYKSDDVVGRVKTYEAIVKGEPIPRPGVPESFRVLVKELQALGLDMK
ECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
VLGGDDQEVELRDMDEEDDDVVNVDALSKYAEKQNEKTNASAEEAKAPSTESAPVETKNN
EECCCCCEEEEECCCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCC
QN
CC
>Mature Secondary Structure 
AGHLVKYGKHRTRRSYARIKEVLDLPNLIEIQSDSYQWFLDEGLREMFNDIMPIEDFAG
CCCCCHHCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEHHHHHHHHHHHHCCCHHHHCC
KLSLEFVDYQLLEPKYTVDEAREHEANYSAPLHVTLRLTNHETGEIKSQDVFFGDFPLMT
CEEEEEECEEECCCCCCHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCCEEE
EQGTFIINGAERVIVSQLVRSPGVYYNLDTDKNNRKIWGTTVIPNRGAWLEYETDAKEIS
CCCCEEECCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEEECCCCCCEEEECCCCCCEE
YVRIDRTRKIPMTELVRALGFGSDEEIIDIFGGSDSLDFTLDKDVHKNPEDSRVAESLKD
EEEECCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCEEEECCCCCCCCCHHHHHHHHHH
IYERLRPGEPKTADSSRSLLTARFFDPKRYDMAPVGRYKVNKKLSLKTRLLGQTLAETLA
HHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHC
DPDTGEVIAQKGEMVNKDVMKKLAVFLDRPDFKMVTYQPSEEAVVTEPMTIQVIKVQDPN
CCCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEECCEEEEEEEECCCC
DPERTLNMIGNGNIDAKLKHITPADIIASMNYFFLLQDGIGSTDDIDHLGNRRIRSVGEL
CHHHHHHHHCCCCCCEEEECCCHHHHHHCCCEEEEEECCCCCCCCHHHHCCHHHHHHHHH
LQNQFRIGLSRMERVVRERMSIQDAETVTPQQLINIRPVVAATKEFFGSSQLSQFMDQTN
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCHHHHHHHHHHCHHHHHHHHHCCC
PLGELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLASYG
CHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHC
KINRYGFIETPYRRVSWEDHKVTDRIDYLTADEEDQFVIAQANSPLNDDGSFADDVVMAR
CCCCCCCCCCCHHHCCCCCCCHHHHHHEEECCCCCCEEEEECCCCCCCCCCCHHHHHEEE
HESDNIETSIENVDYMDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLVDPHS
CCCCCCHHHHCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCC
PLIGTGIEYKAAHDSGVALLCQHAGVVEYVDAREVRVRRDDGALDTYKLMKFRRSNGGKN
CCCCCCCEEEECCCCCEEEEECCCCCEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCC
YNQRPIVRVNDKVDADEVLADGPSMEQGELALGQNPLIAFMTWQGYNFEDAIAINERLVR
CCCCCEEEECCCCCHHHHHCCCCCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHH
DDVYTSIHIEEYESEARDTKLGPEEMTREIPNIGEDALRNLDQDGIVRVGAEVEDGDILV
HHHHEEEEEHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHCCCCCCEEEECCEECCCCEEE
GKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLRVPHGGGGIVQDVKIFTRENGDELSP
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCEEEEEEECCCCCCCCC
GVNMMVRVYIAQKRKLQVGDKMAGRHGNKGTVSVVIPQEDMPYMPDGTPIDIMLSPMGVP
CHHEEEEEEEHHCCHHCCCHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCC
SRMNIGQVLELHLGMAARNLGIHMTTPVFDGAQDKDIWEAVAEAGMDSDAKSVLYDGRTG
CCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHHEECCCCC
EPFEQRVAVGVMHYMKLAHMVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWAL
CCHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCHHEEECCCCCCCCCCCCCCCCCEEEEEE
EAYGAAYTLQEILTYKSDDVVGRVKTYEAIVKGEPIPRPGVPESFRVLVKELQALGLDMK
ECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
VLGGDDQEVELRDMDEEDDDVVNVDALSKYAEKQNEKTNASAEEAKAPSTESAPVETKNN
EECCCCCEEEEECCCCCCCCEEEHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCC
QN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA