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The map label for this gene is xpt

Identifier: 116493119

GI number: 116493119

Start: 1363579

End: 1364151

Strand: Reverse

Name: xpt

Synonym: PEPE_1374

Alternate gene names: 116493119

Gene position: 1364151-1363579 (Counterclockwise)

Preceding gene: 116493120

Following gene: 116493118

Centisome position: 74.45

GC content: 35.78

Gene sequence:

>573_bases
ATGAAGTTACTTGAAGATAAGATTAAGTCCGAAGGAATCGTATTACCAAACAACGTTTTAAAGGTAGATGGTTTTTTAAA
TCACCAGGTGGATGCTCAATTGATGTTTGAAATTGGCAAAGAATTTGGACGTTTATTTAAAAAACAGAACGTAACAAAGA
TTTTAACGGTTGAATCTTCAGGAATTGCCCCTGCTGTAATGACTGGCTTAGCAATGGATGTGCCAGTTGTTTTCGCTAGA
AAGCATAAGAGCTTGACCCTTACTGATGATTTATACACAGCGTCAGTTTACTCATATACAAAGCAAACTAGTAATCAAAT
CTCTATTTCAAAACGGTTTATTGATGAAAAAGATCGAGTTTTGATTATTGATGATTTTTTGGCTAATGGCCAAGCGGTTT
CTGGATTGCTTGATATTGCGGATGCAGCTAATATCGATGTAGTGGGAGTCGGAATTGTGATTGAAAAGACTTTCCAAAAG
GGAAGCCAAATTATTAAAGACCGTGACATTCAGTTAGAATCTTTAGCAAGAATTAAGGCGCTAACGGATGATGGTCAAGT
TGAATTTGAATAA

Upstream 100 bases:

>100_bases
GTATGATGCCCAATATGCAACTGATCCGGATTATCCTAGTAAATTAATTAATTTAATTCAAAAATATGGTTTAAATAACT
ATGATAAATAGGGGGATATT

Downstream 100 bases:

>100_bases
ATAAGTAAGAAGATTGATGAACAGGCGGGATGATTTAAGTGGAGAGTGAAGTAATTACCTCTAGAAAAATTATTTATCCA
GGGGACATAATTGGTATTAT

Product: adenine/guanine phosphoribosyltransferase-like protein

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MKLLEDKIKSEGIVLPNNVLKVDGFLNHQVDAQLMFEIGKEFGRLFKKQNVTKILTVESSGIAPAVMTGLAMDVPVVFAR
KHKSLTLTDDLYTASVYSYTKQTSNQISISKRFIDEKDRVLIIDDFLANGQAVSGLLDIADAANIDVVGVGIVIEKTFQK
GSQIIKDRDIQLESLARIKALTDDGQVEFE

Sequences:

>Translated_190_residues
MKLLEDKIKSEGIVLPNNVLKVDGFLNHQVDAQLMFEIGKEFGRLFKKQNVTKILTVESSGIAPAVMTGLAMDVPVVFAR
KHKSLTLTDDLYTASVYSYTKQTSNQISISKRFIDEKDRVLIIDDFLANGQAVSGLLDIADAANIDVVGVGIVIEKTFQK
GSQIIKDRDIQLESLARIKALTDDGQVEFE
>Mature_190_residues
MKLLEDKIKSEGIVLPNNVLKVDGFLNHQVDAQLMFEIGKEFGRLFKKQNVTKILTVESSGIAPAVMTGLAMDVPVVFAR
KHKSLTLTDDLYTASVYSYTKQTSNQISISKRFIDEKDRVLIIDDFLANGQAVSGLLDIADAANIDVVGVGIVIEKTFQK
GSQIIKDRDIQLESLARIKALTDDGQVEFE

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_PEDPA (Q03EG0)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804854.1
- ProteinModelPortal:   Q03EG0
- SMR:   Q03EG0
- STRING:   Q03EG0
- GeneID:   4416989
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1374
- NMPDR:   fig|278197.10.peg.1208
- eggNOG:   COG0503
- HOGENOM:   HBG288993
- OMA:   ATVYSFT
- BioCyc:   PPEN278197:PEPE_1374-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 21003; Mature: 21003

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLEDKIKSEGIVLPNNVLKVDGFLNHQVDAQLMFEIGKEFGRLFKKQNVTKILTVESS
CCCHHHHHCCCCEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMTGLAMDVPVVFARKHKSLTLTDDLYTASVYSYTKQTSNQISISKRFIDEKDRV
CCCHHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHHHHCCCEEEHHHHHCCCCCCE
LIIDDFLANGQAVSGLLDIADAANIDVVGVGIVIEKTFQKGSQIIKDRDIQLESLARIKA
EEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHH
LTDDGQVEFE
CCCCCCEEEC
>Mature Secondary Structure
MKLLEDKIKSEGIVLPNNVLKVDGFLNHQVDAQLMFEIGKEFGRLFKKQNVTKILTVESS
CCCHHHHHCCCCEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
GIAPAVMTGLAMDVPVVFARKHKSLTLTDDLYTASVYSYTKQTSNQISISKRFIDEKDRV
CCCHHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHHHHCCCEEEHHHHHCCCCCCE
LIIDDFLANGQAVSGLLDIADAANIDVVGVGIVIEKTFQKGSQIIKDRDIQLESLARIKA
EEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEHHHHHHHHHHHCCCCCHHHHHHHHH
LTDDGQVEFE
CCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA