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The map label for this gene is isaA [H]

Identifier: 116493102

GI number: 116493102

Start: 1342809

End: 1343495

Strand: Reverse

Name: isaA [H]

Synonym: PEPE_1356

Alternate gene names: 116493102

Gene position: 1343495-1342809 (Counterclockwise)

Preceding gene: 116493103

Following gene: 116493101

Centisome position: 73.32

GC content: 39.3

Gene sequence:

>687_bases
ATGTCATTTAAGAGTAAATTTTCAAAACTTTCTATCGCATTACTATCAGGTGCCGCAATTGGTGCCGCAATGATTACAAC
AGGCGGTAGCGCAAATGCCGACGAAATTTACACAGTAAAATCTGGTGATACTCTCTCAGAAATTAGTTACGCATTCAACT
TGAATGGTGACTACAATTCAATTGCTAAAGCAAATAACATTAAAAACGTTGATGTTATCAATGTAGGACAAAAGTTAGTT
ATTACTAATGGTGGGGACATCAAGAAAGCTACTAAATCAGAAGTCAAATCACTTCCAGAAGTAGCTAAGAATACTAACGC
TGCCAATGCAGCTACTACAAGCACAACAAATAATACAACTACAACTAACAATGCTGCTTCAACTCAAACAACAGCTAAAT
CAAGCTATGTTGCTCCAGCTCAAAGTAGCACAACAACAAGCAGTTCAAATGGCGGATCAGTAGCTCAACAAATGGCTGCT
AAGACCGGTGTTTCAGCTGCTACATGGCAACGGATTATCAACCGTGAATCTGGTGGTAATGCTAATGCTGTAAATGCTTC
ATCAGGGGCATACGGTTATTTCCAACTATTAGGTCATGGTGAACATGCTGGCATGTCAACTTCAGAACAAGTTAACATGG
CTGCTAGTGTATATAAAGCTCAAGGTATGTCTGCTTGGGGTGAATAA

Upstream 100 bases:

>100_bases
GAAATTACAAATATACCTGTAATATACTTCCTGTAAAGTTATTTCTTGTCGAAAAGAAGCAAGGATATGTTTTTTTAAAA
TAAAGGAGATATTTATCTAT

Downstream 100 bases:

>100_bases
GCAAAAGTAACGTCTTTATAGACACTTTTGTGACAGAGGAAAGTTTTCTTTCCCCTGTTTTTTTATTAAAAACGTCCTAA
AATATAAAGTTTTTTAGAAG

Product: hypothetical protein

Products: NA

Alternate protein names: Immunodominant staphylococcal antigen A [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSFKSKFSKLSIALLSGAAIGAAMITTGGSANADEIYTVKSGDTLSEISYAFNLNGDYNSIAKANNIKNVDVINVGQKLV
ITNGGDIKKATKSEVKSLPEVAKNTNAANAATTSTTNNTTTTNNAASTQTTAKSSYVAPAQSSTTTSSSNGGSVAQQMAA
KTGVSAATWQRIINRESGGNANAVNASSGAYGYFQLLGHGEHAGMSTSEQVNMAASVYKAQGMSAWGE

Sequences:

>Translated_228_residues
MSFKSKFSKLSIALLSGAAIGAAMITTGGSANADEIYTVKSGDTLSEISYAFNLNGDYNSIAKANNIKNVDVINVGQKLV
ITNGGDIKKATKSEVKSLPEVAKNTNAANAATTSTTNNTTTTNNAASTQTTAKSSYVAPAQSSTTTSSSNGGSVAQQMAA
KTGVSAATWQRIINRESGGNANAVNASSGAYGYFQLLGHGEHAGMSTSEQVNMAASVYKAQGMSAWGE
>Mature_227_residues
SFKSKFSKLSIALLSGAAIGAAMITTGGSANADEIYTVKSGDTLSEISYAFNLNGDYNSIAKANNIKNVDVINVGQKLVI
TNGGDIKKATKSEVKSLPEVAKNTNAANAATTSTTNNTTTTNNAASTQTTAKSSYVAPAQSSTTTSSSNGGSVAQQMAAK
TGVSAATWQRIINRESGGNANAVNASSGAYGYFQLLGHGEHAGMSTSEQVNMAASVYKAQGMSAWGE

Specific function: Is able to cleave peptidoglycan [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase family. IsaA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010618 [H]

Pfam domain/function: PF06737 Transglycosylas [H]

EC number: NA

Molecular weight: Translated: 23274; Mature: 23143

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKSKFSKLSIALLSGAAIGAAMITTGGSANADEIYTVKSGDTLSEISYAFNLNGDYNS
CCCHHHHHHHHHHHHCCCHHCEEEEECCCCCCCCEEEEEECCCCHHHEEEEEECCCCHHH
IAKANNIKNVDVINVGQKLVITNGGDIKKATKSEVKSLPEVAKNTNAANAATTSTTNNTT
HHHHCCCCCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
TTNNAASTQTTAKSSYVAPAQSSTTTSSSNGGSVAQQMAAKTGVSAATWQRIINRESGGN
CCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
ANAVNASSGAYGYFQLLGHGEHAGMSTSEQVNMAASVYKAQGMSAWGE
CCEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SFKSKFSKLSIALLSGAAIGAAMITTGGSANADEIYTVKSGDTLSEISYAFNLNGDYNS
CCHHHHHHHHHHHHCCCHHCEEEEECCCCCCCCEEEEEECCCCHHHEEEEEECCCCHHH
IAKANNIKNVDVINVGQKLVITNGGDIKKATKSEVKSLPEVAKNTNAANAATTSTTNNTT
HHHHCCCCCCEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
TTNNAASTQTTAKSSYVAPAQSSTTTSSSNGGSVAQQMAAKTGVSAATWQRIINRESGGN
CCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
ANAVNASSGAYGYFQLLGHGEHAGMSTSEQVNMAASVYKAQGMSAWGE
CCEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA