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The map label for this gene is atpA

Identifier: 116493067

GI number: 116493067

Start: 1308250

End: 1309767

Strand: Reverse

Name: atpA

Synonym: PEPE_1319

Alternate gene names: 116493067

Gene position: 1309767-1308250 (Counterclockwise)

Preceding gene: 116493068

Following gene: 116493066

Centisome position: 71.48

GC content: 41.11

Gene sequence:

>1518_bases
ATGAGCATTAAGGCTGAGGAAATCAGTGCTCTAATCAAACAGCAATTAGAAAACTACCAAGCTGAGCTTAATGTCGAAGA
AACTGGTACCGTTACATATGTTGGTGATGGTATTGCTCGTGCTCATGGCTTAAATAATGCTCTTTCTGGTGAACTTCTAG
AATTCTCTAACGGTGTTTTCGGTATGGTTCAAAACCTTGAATCAAACGATGTTGGTATTGTTATCATGGGTAACTATGAT
GGTATCCACGAAGGAGACGTAGTTAAGAGAACTGGTCGTATCATGGAAGTTCCAGTTGGAGATGCCTTAATTGGTCGAGT
TGTTAACCCATTGGGTGAACCACTTGATGGCAAGGGAGCAATCCAAACCACCAAAACCCGTCCGGTAGAAAATAAGGCAC
CTGGTGTTATGCAACGTAAATCAGTTGAACAACCACTTCAAACAGGTATTAAAGCTATCGATGCTTTAGTTCCAATTGGT
CGTGGACAACGTGAATTGATTATCGGTGACCGTAAGACAGGTAAGACTACAATCGCTATCGATACAATCTTGAATCAAAA
AGATCAAGATATGATTTGTATCTATGTTGCAATCGGACAAAAGGAATCAACTGTTCGTACACAAGTAGAAACATTGAGAC
GTTACGGTGCGATGGACTATACAATCGTTGTTAGTGCTGGTCCTTCTGAACCAGCTCCAATGTTATATCTTGCTCCTTAT
GCCGGAGCAGCAATGGGTGAAGAATTCATGTACAACGGCAAACATGTTTTGATCGTATACGATGATCTATCAAAACAAGC
TGATGCTTACCGTGAACTCTCATTAATTCTTCGCCGTCCGCCTGGGCGTGAAGCTTACCCTGGTGATATCTTCTATACTC
ACTCACGTTTGCTTGAACGTGCAGCTAAGTTGAGTGATGATTTGGGTGGAGGTTCAATGACTGCTTTGCCTTTCGTTGAA
ACTAAAGCTGGGGATGTTTCAGCTTATATCCCAACTAACGTTATTTCAATCACTGATGGACAAGTGTTCCTTGATGGTGA
TTACTTTAACTCAGGAACTCGTCCAGCTATTGATGCTGGTACTTCTGTTTCTCGTGTTGGTGGGGATGCCCAGATTAAGG
CGATGAAGAAGGTTGCCGGAACTCTTCGTTTGGATTTAGCTTCATATCGTGAATTGGAATCATTTGCTCAATTTGGTTCA
GATTTGGATAAAGCTACTCAAGCTAAGTTGGCTCGTGGTCGTCGGACTGTTGAAGTTCTAAAACAACCACTTCATCAACC
ACTTTCCGTTGAAAACCAAGTTATGATTCTTTATGCATTAACTCATGGTTTCTTGGACAATGTTCCTGTCGATGATATTC
AACGTTTCCAAGATGAACTCTTTGACTATATTGCAAGTAACAATAAGGAGCTCACAGACGAAATCCGTGAAACTAAGCAA
CTTCCTGATACGGACAAGATGGATGCAGCAATTAAATCATTTGCTGAACATTTTCAACCTACAAAGGAAGCTAAATAA

Upstream 100 bases:

>100_bases
CAGATAGTTTGATCTACGATGGTAGTATTCAGACTCAAATTAATCAAATTAGACAGCGCCTAATAGGTTAGCTCGATATT
TGTAAAGAGGTGAAACTTTT

Downstream 100 bases:

>100_bases
GGATATCAGCTAACGAGAGGAAAAGTGGTGAGAATTAATGGCAATATCTGAACAAGATGTAAAGCGTCGAATTGATTCGA
CTAAGAAAACTAGTCAAATT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 505; Mature: 504

Protein sequence:

>505_residues
MSIKAEEISALIKQQLENYQAELNVEETGTVTYVGDGIARAHGLNNALSGELLEFSNGVFGMVQNLESNDVGIVIMGNYD
GIHEGDVVKRTGRIMEVPVGDALIGRVVNPLGEPLDGKGAIQTTKTRPVENKAPGVMQRKSVEQPLQTGIKAIDALVPIG
RGQRELIIGDRKTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRRYGAMDYTIVVSAGPSEPAPMLYLAPY
AGAAMGEEFMYNGKHVLIVYDDLSKQADAYRELSLILRRPPGREAYPGDIFYTHSRLLERAAKLSDDLGGGSMTALPFVE
TKAGDVSAYIPTNVISITDGQVFLDGDYFNSGTRPAIDAGTSVSRVGGDAQIKAMKKVAGTLRLDLASYRELESFAQFGS
DLDKATQAKLARGRRTVEVLKQPLHQPLSVENQVMILYALTHGFLDNVPVDDIQRFQDELFDYIASNNKELTDEIRETKQ
LPDTDKMDAAIKSFAEHFQPTKEAK

Sequences:

>Translated_505_residues
MSIKAEEISALIKQQLENYQAELNVEETGTVTYVGDGIARAHGLNNALSGELLEFSNGVFGMVQNLESNDVGIVIMGNYD
GIHEGDVVKRTGRIMEVPVGDALIGRVVNPLGEPLDGKGAIQTTKTRPVENKAPGVMQRKSVEQPLQTGIKAIDALVPIG
RGQRELIIGDRKTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRRYGAMDYTIVVSAGPSEPAPMLYLAPY
AGAAMGEEFMYNGKHVLIVYDDLSKQADAYRELSLILRRPPGREAYPGDIFYTHSRLLERAAKLSDDLGGGSMTALPFVE
TKAGDVSAYIPTNVISITDGQVFLDGDYFNSGTRPAIDAGTSVSRVGGDAQIKAMKKVAGTLRLDLASYRELESFAQFGS
DLDKATQAKLARGRRTVEVLKQPLHQPLSVENQVMILYALTHGFLDNVPVDDIQRFQDELFDYIASNNKELTDEIRETKQ
LPDTDKMDAAIKSFAEHFQPTKEAK
>Mature_504_residues
SIKAEEISALIKQQLENYQAELNVEETGTVTYVGDGIARAHGLNNALSGELLEFSNGVFGMVQNLESNDVGIVIMGNYDG
IHEGDVVKRTGRIMEVPVGDALIGRVVNPLGEPLDGKGAIQTTKTRPVENKAPGVMQRKSVEQPLQTGIKAIDALVPIGR
GQRELIIGDRKTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRRYGAMDYTIVVSAGPSEPAPMLYLAPYA
GAAMGEEFMYNGKHVLIVYDDLSKQADAYRELSLILRRPPGREAYPGDIFYTHSRLLERAAKLSDDLGGGSMTALPFVET
KAGDVSAYIPTNVISITDGQVFLDGDYFNSGTRPAIDAGTSVSRVGGDAQIKAMKKVAGTLRLDLASYRELESFAQFGSD
LDKATQAKLARGRRTVEVLKQPLHQPLSVENQVMILYALTHGFLDNVPVDDIQRFQDELFDYIASNNKELTDEIRETKQL
PDTDKMDAAIKSFAEHFQPTKEAK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=506, Percent_Identity=56.3241106719368, Blast_Score=573, Evalue=1e-164,
Organism=Homo sapiens, GI4757810, Length=506, Percent_Identity=56.3241106719368, Blast_Score=573, Evalue=1e-164,
Organism=Homo sapiens, GI19913426, Length=300, Percent_Identity=26.3333333333333, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI19913428, Length=300, Percent_Identity=27, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI32189394, Length=381, Percent_Identity=25.1968503937008, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=50.8771929824561, Blast_Score=522, Evalue=1e-149,
Organism=Escherichia coli, GI1788251, Length=323, Percent_Identity=30.6501547987616, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1790170, Length=384, Percent_Identity=27.6041666666667, Blast_Score=113, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71988063, Length=504, Percent_Identity=56.7460317460317, Blast_Score=581, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI71988080, Length=504, Percent_Identity=56.7460317460317, Blast_Score=580, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI71988074, Length=504, Percent_Identity=52.3809523809524, Blast_Score=522, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17510931, Length=364, Percent_Identity=26.0989010989011, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17570191, Length=329, Percent_Identity=24.9240121580547, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=428, Percent_Identity=23.8317757009346, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=66, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71988068, Length=72, Percent_Identity=41.6666666666667, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=510, Percent_Identity=56.2745098039216, Blast_Score=575, Evalue=1e-165,
Organism=Saccharomyces cerevisiae, GI6322581, Length=449, Percent_Identity=25.3897550111359, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319603, Length=303, Percent_Identity=25.4125412541254, Blast_Score=103, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24658560, Length=506, Percent_Identity=55.9288537549407, Blast_Score=567, Evalue=1e-162,
Organism=Drosophila melanogaster, GI281361666, Length=344, Percent_Identity=25.8720930232558, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24646341, Length=344, Percent_Identity=25.8720930232558, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17136796, Length=344, Percent_Identity=25.8720930232558, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28574560, Length=427, Percent_Identity=25.7611241217799, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24638766, Length=379, Percent_Identity=25.8575197889182, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_PEDPA (Q03EL2)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804802.1
- ProteinModelPortal:   Q03EL2
- SMR:   Q03EL2
- STRING:   Q03EL2
- GeneID:   4417006
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1319
- NMPDR:   fig|278197.10.peg.1157
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EMALTLW
- PhylomeDB:   Q03EL2
- ProtClustDB:   PRK09281
- BioCyc:   PPEN278197:PEPE_1319-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 55262; Mature: 55131

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKAEEISALIKQQLENYQAELNVEETGTVTYVGDGIARAHGLNNALSGELLEFSNGVF
CCCCHHHHHHHHHHHHHHHHHEECEECCCEEEEECCCHHHHHCCCCHHCCCHHHHCCCHH
GMVQNLESNDVGIVIMGNYDGIHEGDVVKRTGRIMEVPVGDALIGRVVNPLGEPLDGKGA
HHHHCCCCCCEEEEEECCCCCCCCCCHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCC
IQTTKTRPVENKAPGVMQRKSVEQPLQTGIKAIDALVPIGRGQRELIIGDRKTGKTTIAI
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTILNQKDQDMICIYVAIGQKESTVRTQVETLRRYGAMDYTIVVSAGPSEPAPMLYLAPY
EHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCC
AGAAMGEEFMYNGKHVLIVYDDLSKQADAYRELSLILRRPPGREAYPGDIFYTHSRLLER
CCCHHCHHHEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHH
AAKLSDDLGGGSMTALPFVETKAGDVSAYIPTNVISITDGQVFLDGDYFNSGTRPAIDAG
HHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCCCCCCCCCCCCC
TSVSRVGGDAQIKAMKKVAGTLRLDLASYRELESFAQFGSDLDKATQAKLARGRRTVEVL
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHH
KQPLHQPLSVENQVMILYALTHGFLDNVPVDDIQRFQDELFDYIASNNKELTDEIRETKQ
HHHHCCCCCCCCCEEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
LPDTDKMDAAIKSFAEHFQPTKEAK
CCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SIKAEEISALIKQQLENYQAELNVEETGTVTYVGDGIARAHGLNNALSGELLEFSNGVF
CCCHHHHHHHHHHHHHHHHHEECEECCCEEEEECCCHHHHHCCCCHHCCCHHHHCCCHH
GMVQNLESNDVGIVIMGNYDGIHEGDVVKRTGRIMEVPVGDALIGRVVNPLGEPLDGKGA
HHHHCCCCCCEEEEEECCCCCCCCCCHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCCCC
IQTTKTRPVENKAPGVMQRKSVEQPLQTGIKAIDALVPIGRGQRELIIGDRKTGKTTIAI
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEE
DTILNQKDQDMICIYVAIGQKESTVRTQVETLRRYGAMDYTIVVSAGPSEPAPMLYLAPY
EHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCC
AGAAMGEEFMYNGKHVLIVYDDLSKQADAYRELSLILRRPPGREAYPGDIFYTHSRLLER
CCCHHCHHHEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHH
AAKLSDDLGGGSMTALPFVETKAGDVSAYIPTNVISITDGQVFLDGDYFNSGTRPAIDAG
HHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCCCCCCCCCCCCC
TSVSRVGGDAQIKAMKKVAGTLRLDLASYRELESFAQFGSDLDKATQAKLARGRRTVEVL
CCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHH
KQPLHQPLSVENQVMILYALTHGFLDNVPVDDIQRFQDELFDYIASNNKELTDEIRETKQ
HHHHCCCCCCCCCEEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
LPDTDKMDAAIKSFAEHFQPTKEAK
CCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA