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The map label for this gene is uvrX [H]

Identifier: 116492991

GI number: 116492991

Start: 1228278

End: 1229567

Strand: Reverse

Name: uvrX [H]

Synonym: PEPE_1243

Alternate gene names: 116492991

Gene position: 1229567-1228278 (Counterclockwise)

Preceding gene: 116492992

Following gene: 116492990

Centisome position: 67.1

GC content: 36.59

Gene sequence:

>1290_bases
ATGAATTATGATAAAGAACCCAAGGGTGTTTTTTTAATGATTGATAATAAATCTTTTTATGCCAGCGTTGAAGCAGTTAT
GCGCGGGCTAAATCCATTAAAAGTTGTTATGGTAGTAATTTCTGAGCAGGAAAATACCAATGGTGGACTAATTTTAGCCA
CATCACCGATGGCCAAAAAACTTTTTGGATTGAAAGCTAACGTCTCGCGACAAAGGGATTTACCGTGTGATCCAAGAATT
ATAATGGTCCCACCACGAATGAATCTATATATTAAGCGTAATCTTCAAATTAACGAAATATTTAAACAGTATGTGGCAGA
AGAAGATTTATATCCATATTCCATTGATGAATCAATTTTAGATATTACTAAAACCTGGAAACTTTTTGGAGAAACTCCTG
AAGAAGTTGCTAAAAAAATTCAACATAAAGTACGTAGGCAGTTAGGCTTATACACAACAATCGGTGTCGGTGAAAATCCA
TTGCAAGCTAAACTAGCATTGGATAATTTCGCTAAAAAATCCAATGATTTGATTGGCACAATTACATACAATACAGTAGC
CCAAAAAGTATGGATGATTCCTAAGTTGACAGATGTGTGGGGAATTGGAAGACGGACGACCGAGCGTTTGCAAAAACTGG
GTATTAACAATATGAATGAGTTAGCACATAGTAATCCATATTTTTTAAAACAAGAGTTTGGAATAATTGGAACTCAATTG
TTTGCAACAGCGTGGGGCATTGATCGAACGATTCTAAGTGAAAGGGTAAAACCTAAAGAAAATAGTGTGGGTAATTCCCA
AGTGTTACCTAGAAATTATCAGCAGCAATGTGAAATTGAAACTGTAATTAAAGAGATTAGTGAGCAGGTAGCTGCACGGT
TACGACATCGGTGTCAACAATGTGGTGAGCTAACGTTAAGTATTGGATTTAGTTACCAGTCTACGATAAATAGTGGGTTT
AGCCAGTCATTGAAGGTTATTCCGACTAATAGTAATGTAGAAATTTTTAAATATGCTAAGGAAATTTTCCAAAAGTACTG
GAAAGGGCAACCTGTTCGTAATATAGCTATCTTTACTGCTAAATTGAGCTATCAGATTGGTGAACAATTGAATCTATTCG
AACCGTTTCCGAGGATTTCCAAACATCAAACTGATCAACTGGTTGACCAGATTAGAGCTGAATATGGCTTTACCGCTTTA
GTTTACGCACGTAGCTTAACTAAAGGTGGTACTGCAATCCAGCGGGCCAGCCTAGTAGGTGGACATAATGGGGGGAATGC
TTATGAATAA

Upstream 100 bases:

>100_bases
CTCGTTAATAAGAAACGTTTCTATTTTTAAGAAGCGTTTTTTATTTTTTTCTTGTCAAAAAGAACATATGTTCGTATAAT
TGAGAGCGGAGGCAGATTTA

Downstream 100 bases:

>100_bases
GCAACAAGAATTAACTTTAATTAACCAGCGAATTGAAACACTGTTTAATGTTTCAAAATTTAACACTCAATTTTGGATTG
TAATTGTTAATGATATCTAT

Product: nucleotidyltransferase/DNA polymerase for DNA repair

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MNYDKEPKGVFLMIDNKSFYASVEAVMRGLNPLKVVMVVISEQENTNGGLILATSPMAKKLFGLKANVSRQRDLPCDPRI
IMVPPRMNLYIKRNLQINEIFKQYVAEEDLYPYSIDESILDITKTWKLFGETPEEVAKKIQHKVRRQLGLYTTIGVGENP
LQAKLALDNFAKKSNDLIGTITYNTVAQKVWMIPKLTDVWGIGRRTTERLQKLGINNMNELAHSNPYFLKQEFGIIGTQL
FATAWGIDRTILSERVKPKENSVGNSQVLPRNYQQQCEIETVIKEISEQVAARLRHRCQQCGELTLSIGFSYQSTINSGF
SQSLKVIPTNSNVEIFKYAKEIFQKYWKGQPVRNIAIFTAKLSYQIGEQLNLFEPFPRISKHQTDQLVDQIRAEYGFTAL
VYARSLTKGGTAIQRASLVGGHNGGNAYE

Sequences:

>Translated_429_residues
MNYDKEPKGVFLMIDNKSFYASVEAVMRGLNPLKVVMVVISEQENTNGGLILATSPMAKKLFGLKANVSRQRDLPCDPRI
IMVPPRMNLYIKRNLQINEIFKQYVAEEDLYPYSIDESILDITKTWKLFGETPEEVAKKIQHKVRRQLGLYTTIGVGENP
LQAKLALDNFAKKSNDLIGTITYNTVAQKVWMIPKLTDVWGIGRRTTERLQKLGINNMNELAHSNPYFLKQEFGIIGTQL
FATAWGIDRTILSERVKPKENSVGNSQVLPRNYQQQCEIETVIKEISEQVAARLRHRCQQCGELTLSIGFSYQSTINSGF
SQSLKVIPTNSNVEIFKYAKEIFQKYWKGQPVRNIAIFTAKLSYQIGEQLNLFEPFPRISKHQTDQLVDQIRAEYGFTAL
VYARSLTKGGTAIQRASLVGGHNGGNAYE
>Mature_429_residues
MNYDKEPKGVFLMIDNKSFYASVEAVMRGLNPLKVVMVVISEQENTNGGLILATSPMAKKLFGLKANVSRQRDLPCDPRI
IMVPPRMNLYIKRNLQINEIFKQYVAEEDLYPYSIDESILDITKTWKLFGETPEEVAKKIQHKVRRQLGLYTTIGVGENP
LQAKLALDNFAKKSNDLIGTITYNTVAQKVWMIPKLTDVWGIGRRTTERLQKLGINNMNELAHSNPYFLKQEFGIIGTQL
FATAWGIDRTILSERVKPKENSVGNSQVLPRNYQQQCEIETVIKEISEQVAARLRHRCQQCGELTLSIGFSYQSTINSGF
SQSLKVIPTNSNVEIFKYAKEIFQKYWKGQPVRNIAIFTAKLSYQIGEQLNLFEPFPRISKHQTDQLVDQIRAEYGFTAL
VYARSLTKGGTAIQRASLVGGHNGGNAYE

Specific function: Poorly Processive, Error-Prone DNA Polymerase Involved In Untargeted Mutagenesis. Copies Undamaged DNA At Stalled Replication Forks, Which Arise In Vivo From Mismatched Or Misaligned Primer Ends. These Misaligned Primers Can Be Extended By Poliv. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1786425, Length=365, Percent_Identity=24.1095890410959, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787432, Length=404, Percent_Identity=23.7623762376238, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: 2.7.7.7 [C]

Molecular weight: Translated: 48670; Mature: 48670

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYDKEPKGVFLMIDNKSFYASVEAVMRGLNPLKVVMVVISEQENTNGGLILATSPMAKK
CCCCCCCCEEEEEEECCHHHHHHHHHHHCCCHHHEEEEEEECCCCCCCCEEEECCHHHHH
LFGLKANVSRQRDLPCDPRIIMVPPRMNLYIKRNLQINEIFKQYVAEEDLYPYSIDESIL
HHCCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHH
DITKTWKLFGETPEEVAKKIQHKVRRQLGLYTTIGVGENPLQAKLALDNFAKKSNDLIGT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEE
ITYNTVAQKVWMIPKLTDVWGIGRRTTERLQKLGINNMNELAHSNPYFLKQEFGIIGTQL
EEHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCEEHHHHCHHHHHH
FATAWGIDRTILSERVKPKENSVGNSQVLPRNYQQQCEIETVIKEISEQVAARLRHRCQQ
HHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CGELTLSIGFSYQSTINSGFSQSLKVIPTNSNVEIFKYAKEIFQKYWKGQPVRNIAIFTA
HCCEEEEECCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
KLSYQIGEQLNLFEPFPRISKHQTDQLVDQIRAEYGFTALVYARSLTKGGTAIQRASLVG
EHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCC
GHNGGNAYE
CCCCCCCCC
>Mature Secondary Structure
MNYDKEPKGVFLMIDNKSFYASVEAVMRGLNPLKVVMVVISEQENTNGGLILATSPMAKK
CCCCCCCCEEEEEEECCHHHHHHHHHHHCCCHHHEEEEEEECCCCCCCCEEEECCHHHHH
LFGLKANVSRQRDLPCDPRIIMVPPRMNLYIKRNLQINEIFKQYVAEEDLYPYSIDESIL
HHCCCCCCCCCCCCCCCCEEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHH
DITKTWKLFGETPEEVAKKIQHKVRRQLGLYTTIGVGENPLQAKLALDNFAKKSNDLIGT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCEEEE
ITYNTVAQKVWMIPKLTDVWGIGRRTTERLQKLGINNMNELAHSNPYFLKQEFGIIGTQL
EEHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCEEHHHHCHHHHHH
FATAWGIDRTILSERVKPKENSVGNSQVLPRNYQQQCEIETVIKEISEQVAARLRHRCQQ
HHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CGELTLSIGFSYQSTINSGFSQSLKVIPTNSNVEIFKYAKEIFQKYWKGQPVRNIAIFTA
HCCEEEEECCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
KLSYQIGEQLNLFEPFPRISKHQTDQLVDQIRAEYGFTALVYARSLTKGGTAIQRASLVG
EHHHHHCCCCCCCCCCCCHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHCC
GHNGGNAYE
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]