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The map label for this gene is ftsK [H]

Identifier: 116492955

GI number: 116492955

Start: 1194198

End: 1196549

Strand: Reverse

Name: ftsK [H]

Synonym: PEPE_1194

Alternate gene names: 116492955

Gene position: 1196549-1194198 (Counterclockwise)

Preceding gene: 116492956

Following gene: 116492953

Centisome position: 65.3

GC content: 37.46

Gene sequence:

>2352_bases
ATGGCAAAAACAAGAAAAAAACGAAAAACAAAGACAAGACGTAAAACTAAGCAAAAGACCCAAGTACCAACAAAAAATCT
TTTAGGTTTAACTTACGTTTTAGTTGCAATATTAGGGTATTTTGGTCGAGGATTTCTAGGAATTTTAGTCGCTAACATGT
TTAGAATCTTTGTTGGTAGTCTTAGCCCAATTTTATTCATTATTCTATTCATCTATGGATTGTATCTTTTATTCATGGGA
AAAGAATTGTCTTTTAATGGAATAACAGATCGAGTAATTGGACTTAGCTTGACTTTGTTAGGATATTTATTGTGGGTAGA
GTATCAATTTGCCAGTAGCTTAAGATTAGAAAATGGGTTTATCAGTCGGGCCATTGATGGCATTGAACGATCCTTTCTAG
AACAAACCTCTACAAATGATGTTGGAGGAGGAATTGGTGGAGCAACTTTATATACCGCAACTCATTTTTTGCTTAGCAGC
GTAGGGAGCATGCTCTTTTCAGTTATTCTAATGGGGATGGGGCTGGTAGTTCTGTTTGGTATCCCATTTGATCAAGTTTT
GGAAAAAATTGGAATTGGATTTGCTTGGACCATACGACATGCGATCGCTAGTTTTAAATCTGCTGCAAACAATGTATACG
ACTGGTTCAGCAATTTAGATTTTTCAGAAAAAGAACAATCAAAAACCAGAAATGAATCAAGTAAAACGGATGTTACTCGA
TCAATGCACAGGGCATCTAAACCAGCAGTTGAAGTTACCAAAACGGATGAAAAAGTTTTGGAAGAACCTATCGTTGATGG
AACTAGAGGAACCGAACATCCAATTGAACCAAAAATTGAAATTGCGACTACTAATAAAATTCAACGTAAACCTAAGAATC
AGGTTAACAATGATGATTTAGAAATTAATAGTGGATTTGATAGTGAGTCTAAGACTAATCCTAATTATCGCTTACCATCA
TCGGAACTATTAACTGAAATTCCACAAACAGACCAGAGTTCCGAATATTCTTCAATTAAAAAGAATACTAAAATTTTACA
AGATACTTTAAATAGTTTTGGAGTTGATGCTTCCGTTGAAAGCGTGAAGATGGGGCCTTCTGTGACGGAATACGAAATTC
ATCCAGCGATTGGTGTTAAAGTTAGTAAAATTGTTGGCTTGGCCGATGACTTAGCGTTAGCTCTAGCCGCAAAAGATATT
CGTATTGAAGCTCCAATTCCGGGAAAGTCATTAATTGGAATTGAGGTTCCCAATCGAACAATTTCGACAGTTTCATTTAG
AGACATTATTGAATCTCAACCGGCCCATCCAGAAGACCCACTTAAAGTTCCTGTTGGTCGGGATGTTTCGGGTAATCTGG
TAGAAGCTAACTTAGTTAAAATGCAGCATTTACTAATTGCGGGAGCTACAGGTTCTGGAAAATCAGTGATGATTAATGTC
ATTATTACCGGAATCTTAATGAATGCTCGTCCAGATGAGGTTAAATTAATTCTAATTGATCCTAAGAAGGTAGAACTTGG
AATCTATAATGACATTCCGCATCTACTAACCCCAGTGGTGACCGATGCTAGAAAAGCTGCTAAAGCGCTGCATAAGGTGG
TCGCAGAGATGCAACATCGATATGATTTGTTTGCTGAACTAAATCAACGAAATATTAAAAGCTACAATGATTTCATCGAA
GAACAGAATGCAGCAGACGGGATGAATCGCCCAAAAATGCCATATATTGTGGTTGTGGTTGATGAACTTTCTGATTTAAT
GATGGTAGCTTCCAATGAAGTTGAAGATGCAATTATTAGGCTGGCACAGCTTGCACGTGCTGCAGGAATACATATGATTA
TTGCGACACAACGTCCGTCCGTTAACGTGGTTACCGGTTTGATTAAAGCTAATGTGCCATCCAGAATTGCCTTTGCGGTA
GCATCGGGAATCGATTCGAGAACAATCATTGATGCTAATGGAGCAGAGAAGTTATTAGGAAGAGGAGATATGTTGTTCTT
TCCGATGGGTCAGAACAAGCCTGAACGTGTACAAGGGGCATTTATTTCGGATCATGATGTTAAGGAGATTATTGATTTTG
TTAAGAAACAACAATCTGCTGACTATGATGAAACTTTAGATATTAGTGACCAAGAAATTGAAGAAAATGATAGTGGGGAA
TTAGATGAGTATTATGCGGAAGCTGTTCAATTAGTAACAGATATGCAAAGGGCAAGTACTTCAATGCTTCAAAGGAAGTT
CCGAGTGGGATATAATCGCGCTGCCCGTATTATGGATCAACTTGAAGATAATGGTATCATCGGTCCTCAAGAAGGTAGTA
AACCTCGTAAAGTATATCGTGAAAAAGAATAA

Upstream 100 bases:

>100_bases
CAGCGGCGATTGTAATTTATGAAGTGTTACGTCAACAAGGATTCCCTAATTTAGAGATGAGCCATTTGTATGAAAATGAT
AAATTAAAATAGGATTTGAT

Downstream 100 bases:

>100_bases
AAAAGATTTAAGACAATCTGTCTTAAATCTTTTTTTTTATATTCTGATTAATTTGCACCAAACAATTGAGCCAGAGGAGC
GTAAAGCACACTTCCCAAGG

Product: DNA segregation ATPase FtsK/SpoIIIE related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 783; Mature: 782

Protein sequence:

>783_residues
MAKTRKKRKTKTRRKTKQKTQVPTKNLLGLTYVLVAILGYFGRGFLGILVANMFRIFVGSLSPILFIILFIYGLYLLFMG
KELSFNGITDRVIGLSLTLLGYLLWVEYQFASSLRLENGFISRAIDGIERSFLEQTSTNDVGGGIGGATLYTATHFLLSS
VGSMLFSVILMGMGLVVLFGIPFDQVLEKIGIGFAWTIRHAIASFKSAANNVYDWFSNLDFSEKEQSKTRNESSKTDVTR
SMHRASKPAVEVTKTDEKVLEEPIVDGTRGTEHPIEPKIEIATTNKIQRKPKNQVNNDDLEINSGFDSESKTNPNYRLPS
SELLTEIPQTDQSSEYSSIKKNTKILQDTLNSFGVDASVESVKMGPSVTEYEIHPAIGVKVSKIVGLADDLALALAAKDI
RIEAPIPGKSLIGIEVPNRTISTVSFRDIIESQPAHPEDPLKVPVGRDVSGNLVEANLVKMQHLLIAGATGSGKSVMINV
IITGILMNARPDEVKLILIDPKKVELGIYNDIPHLLTPVVTDARKAAKALHKVVAEMQHRYDLFAELNQRNIKSYNDFIE
EQNAADGMNRPKMPYIVVVVDELSDLMMVASNEVEDAIIRLAQLARAAGIHMIIATQRPSVNVVTGLIKANVPSRIAFAV
ASGIDSRTIIDANGAEKLLGRGDMLFFPMGQNKPERVQGAFISDHDVKEIIDFVKKQQSADYDETLDISDQEIEENDSGE
LDEYYAEAVQLVTDMQRASTSMLQRKFRVGYNRAARIMDQLEDNGIIGPQEGSKPRKVYREKE

Sequences:

>Translated_783_residues
MAKTRKKRKTKTRRKTKQKTQVPTKNLLGLTYVLVAILGYFGRGFLGILVANMFRIFVGSLSPILFIILFIYGLYLLFMG
KELSFNGITDRVIGLSLTLLGYLLWVEYQFASSLRLENGFISRAIDGIERSFLEQTSTNDVGGGIGGATLYTATHFLLSS
VGSMLFSVILMGMGLVVLFGIPFDQVLEKIGIGFAWTIRHAIASFKSAANNVYDWFSNLDFSEKEQSKTRNESSKTDVTR
SMHRASKPAVEVTKTDEKVLEEPIVDGTRGTEHPIEPKIEIATTNKIQRKPKNQVNNDDLEINSGFDSESKTNPNYRLPS
SELLTEIPQTDQSSEYSSIKKNTKILQDTLNSFGVDASVESVKMGPSVTEYEIHPAIGVKVSKIVGLADDLALALAAKDI
RIEAPIPGKSLIGIEVPNRTISTVSFRDIIESQPAHPEDPLKVPVGRDVSGNLVEANLVKMQHLLIAGATGSGKSVMINV
IITGILMNARPDEVKLILIDPKKVELGIYNDIPHLLTPVVTDARKAAKALHKVVAEMQHRYDLFAELNQRNIKSYNDFIE
EQNAADGMNRPKMPYIVVVVDELSDLMMVASNEVEDAIIRLAQLARAAGIHMIIATQRPSVNVVTGLIKANVPSRIAFAV
ASGIDSRTIIDANGAEKLLGRGDMLFFPMGQNKPERVQGAFISDHDVKEIIDFVKKQQSADYDETLDISDQEIEENDSGE
LDEYYAEAVQLVTDMQRASTSMLQRKFRVGYNRAARIMDQLEDNGIIGPQEGSKPRKVYREKE
>Mature_782_residues
AKTRKKRKTKTRRKTKQKTQVPTKNLLGLTYVLVAILGYFGRGFLGILVANMFRIFVGSLSPILFIILFIYGLYLLFMGK
ELSFNGITDRVIGLSLTLLGYLLWVEYQFASSLRLENGFISRAIDGIERSFLEQTSTNDVGGGIGGATLYTATHFLLSSV
GSMLFSVILMGMGLVVLFGIPFDQVLEKIGIGFAWTIRHAIASFKSAANNVYDWFSNLDFSEKEQSKTRNESSKTDVTRS
MHRASKPAVEVTKTDEKVLEEPIVDGTRGTEHPIEPKIEIATTNKIQRKPKNQVNNDDLEINSGFDSESKTNPNYRLPSS
ELLTEIPQTDQSSEYSSIKKNTKILQDTLNSFGVDASVESVKMGPSVTEYEIHPAIGVKVSKIVGLADDLALALAAKDIR
IEAPIPGKSLIGIEVPNRTISTVSFRDIIESQPAHPEDPLKVPVGRDVSGNLVEANLVKMQHLLIAGATGSGKSVMINVI
ITGILMNARPDEVKLILIDPKKVELGIYNDIPHLLTPVVTDARKAAKALHKVVAEMQHRYDLFAELNQRNIKSYNDFIEE
QNAADGMNRPKMPYIVVVVDELSDLMMVASNEVEDAIIRLAQLARAAGIHMIIATQRPSVNVVTGLIKANVPSRIAFAVA
SGIDSRTIIDANGAEKLLGRGDMLFFPMGQNKPERVQGAFISDHDVKEIIDFVKKQQSADYDETLDISDQEIEENDSGEL
DEYYAEAVQLVTDMQRASTSMLQRKFRVGYNRAARIMDQLEDNGIIGPQEGSKPRKVYREKE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=500, Percent_Identity=44.4, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 86688; Mature: 86557

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure 
AKTRKKRKTKTRRKTKQKTQVPTKNLLGLTYVLVAILGYFGRGFLGILVANMFRIFVGS
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSPILFIILFIYGLYLLFMGKELSFNGITDRVIGLSLTLLGYLLWVEYQFASSLRLENGF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ISRAIDGIERSFLEQTSTNDVGGGIGGATLYTATHFLLSSVGSMLFSVILMGMGLVVLFG
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPFDQVLEKIGIGFAWTIRHAIASFKSAANNVYDWFSNLDFSEKEQSKTRNESSKTDVTR
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHH
SMHRASKPAVEVTKTDEKVLEEPIVDGTRGTEHPIEPKIEIATTNKIQRKPKNQVNNDDL
HHHHCCCCCEEEECCHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHCCCCCCCCCCE
EINSGFDSESKTNPNYRLPSSELLTEIPQTDQSSEYSSIKKNTKILQDTLNSFGVDASVE
EECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHH
SVKMGPSVTEYEIHPAIGVKVSKIVGLADDLALALAAKDIRIEAPIPGKSLIGIEVPNRT
HHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEECCCCC
ISTVSFRDIIESQPAHPEDPLKVPVGRDVSGNLVEANLVKMQHLLIAGATGSGKSVMINV
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECCCCCCCCEEHHH
IITGILMNARPDEVKLILIDPKKVELGIYNDIPHLLTPVVTDARKAAKALHKVVAEMQHR
HHHHHHHCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YDLFAELNQRNIKSYNDFIEEQNAADGMNRPKMPYIVVVVDELSDLMMVASNEVEDAIIR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHHH
LAQLARAAGIHMIIATQRPSVNVVTGLIKANVPSRIAFAVASGIDSRTIIDANGAEKLLG
HHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEECCCHHHHHC
RGDMLFFPMGQNKPERVQGAFISDHDVKEIIDFVKKQQSADYDETLDISDQEIEENDSGE
CCCEEEEECCCCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCC
LDEYYAEAVQLVTDMQRASTSMLQRKFRVGYNRAARIMDQLEDNGIIGPQEGSKPRKVYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHC
EKE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]